Results 71 to 80 of about 17,699 (240)

Domestic dog ownership in Iran is a risk factor for human infection with Leishmania infantum. [PDF]

, 2002
One explanation proposed for the widespread failure to control zoonotic visceral leishmaniasis by culling infected domestic dogs is that wild canids or humans play significant roles in transmission.
Davies, Clive R, Edrissian, Gholan H, Gavgani, A Samad Mazloumi, Mohebali, Mehdi, Mohite, Hassan   +4 more
core   +1 more source

Aminophthalocyanine-Mediated Photodynamic Inactivation of Leishmania tropica [PDF]

Antimicrobial Agents and Chemotherapy, 2016
ABSTRACT Photodynamic inactivation of Leishmania spp. requires the cellular uptake of photosensitizers, e.g., endocytosis of silicon(IV)-phthalocyanines (PC) axially substituted with bulky ligands. We report here that when substituted with amino-containing ligands, the PCs (PC1 and PC2) were endocytosed ...
Ahmed, Al-Qahtani, Saad, Alkahtani, Bala, Kolli, Pankaj, Tripathi, Sujoy, Dutta, Abdullah A, Al-Kahtane, Xiong-Jie, Jiang, Dennis K P, Ng, Kwang Poo, Chang   +8 more
openaire   +2 more sources

IL‐12 and IFN‐γ in Response to Leishmania Infantum Antigens in Felines From an Endemic Area for Visceral Leishmaniasis

Parasite Immunology, Volume 47, Issue 8, August 2025.
ABSTRACT Visceral leishmaniasis is a potentially fatal zoonosis with an increasing incidence. Most infected felines present the disease in its subclinical form and demonstrate greater resistance to parasitemia than dogs. However, the role of cellular immunity in felines is still poorly understood. This study measured serum levels of interleukin (IL)‐12
João Victor Lé Lode, Lucas Takeshi Siqueira Ito, Gisele Mitsue Umino, Valéria Marçal Felix de Lima   +3 more
wiley   +1 more source

Integration of Machine Learning‐QSAR and Polypharmacology in Drug Discovery for Leishmaniasis Using Natural and Repurposed Compounds

ChemistrySelect, Volume 10, Issue 21, June 4, 2025.
Leishmaniasis affects over 1 billion people worldwide, with current treatments limited by toxicity and efficacy. This study used machine learning (ML), QSAR, and polypharmacology to identify potential drug candidates, analyzing 12,072 compounds with random forest and XGBoost models.
Laís Salvador do Amaral, Amiel Artur Morais, Alexandre de Fátima Cobre, Raul Edison Luna Lazo, Dile Pontarolo Stremel, Jaqueline Carneiro, Luana Mota Ferreira, Roberto Pontarolo   +7 more
wiley   +1 more source

Lupoid leishmaniasis among the known cases of cutaneous leishmaniasis in Herat Province, western Afghanistan

Journal of Infection and Public Health, 2016
Summary: Lupoid cutaneous leishmaniasis (LCL) is an uncommon form of chronic cutaneous leishmaniasis, which is mostly caused by Leishmania tropica in the Old World and has a high incidence throughout early life.
Hossein Pazoki, Mahdi Fakhar, Abobakar Rasooli, Mehdi Karamian, Eisa Nazar   +4 more
doaj   +1 more source

Leishmaniasis in Patients With Inflammatory Bowel Disease: A National Multicenter Study of GETECCU

United European Gastroenterology Journal, Volume 13, Issue 5, Page 674-684, June 2025.
ABSTRACT Background Leishmaniasis (LI) is a vector‐borne illness caused by a protozoan of the genus Leishmania. Data on the features of LI in patients with inflammatory bowel disease (IBD) are scarce. Aim To describe the characteristics of patients with IBD who present with leishmaniasis, infection outcomes and the risk factors associated with ...
L Madero‐Velázquez, A Mínguez, L Mayorga, JJ Ramírez, N Moreno, C Amorós, MA Nieto, R Mena, JM Benítez, L Gimeno‐Pitarch, N Maroto, C Suria, F Rodríguez‐Moranta, I Ordás, L Ruiz, MA García‐Brenes, A Martín‐Cardona, C Rubín de Célix, K Cárdenas, D Ginard, L Medina, N Pedrero, R Plaza, R Salmoral, TJ Martínez‐Pérez, V Algara, E Merino, Y Zabana, A Gutiérrez, on behalf of Young Group of GETECCU   +29 more
wiley   +1 more source

Leishmania tropica

, 2010
Cutaneous Leishmaniasis (CL), or oriental sore, is mainly caused by Leishmania tropica and L. major in the Old World. CL due to L. tropica has become a major public health problem in different endemic foci due to recent outbreaks in several urban areas. The disease caused by L. tropica presents varying clinical manifestations and complications.
openaire   +2 more sources

Mesenchymal Stem Cells: A Double‐Edged Approach for Managing Cutaneous Leishmaniasis Lesions

International Wound Journal, Volume 22, Issue 6, June 2025.
ABSTRACT Leishmania spp. are intracellular protozoan parasites responsible for leishmaniasis, a globally prevalent vector‐borne disease transmitted by phlebotomine sandflies. Within vertebrate hosts, the parasites preferentially infect macrophages and dendritic cells, leading to cell lysis and the formation of disfiguring lesions.
Masoud Foroutan, Hamidreza Majidiani, Hany M. Elsheikha, Ali Saeedi‐Boroujeni, Saeed Bahadory, Reza Saberi, Ana Shirzadshahrivar, Seyed Mahmoud Hashemi, Sara Soudi   +8 more
wiley   +1 more source

Disseminated Leishmaniasis Caused by Leishmania Tropica in a Puppy from Karaj, Central Iran [PDF]

Iranian Journal of Parasitology, 2011
A 5-month old puppy with muco-cutaneous lesions in the chin, around lips and eyes was exam­ined physically and microscopically for leishmaniasis. Muco-cutaneous lesions containing a large num­ber of amastigotes of Leishmania spp.
M Mohebali, A Malmasi, H Hajjaran, S Jamshidi, B Akhoundi, M Rezaei, S Jani­tabar, H Zarei, S Charehdar   +8 more
doaj   +2 more sources

Characterization of Allobodo yubaba sp. nov. and Novijibodo darinka gen. et sp. nov., cultivable free‐living species of the phylogenetically enigmatic kinetoplastid taxon Allobodonidae

Journal of Eukaryotic Microbiology, Volume 72, Issue 1, January/February 2025.
Abstract Kinetoplastids are a large and diverse protist group, spanning ecologically important free‐living forms to medically important parasites. The taxon Allobodonidae holds an unresolved position within kinetoplastids, and the sole described species, Allobodo chlorophagus, is uncultivated, being a necrotroph/parasite of macroalgae. Here we describe
Julia A. Packer, Daryna Zavadska, Elizabeth J. Weston, Yana Eglit, Daniel J. Richter, Alastair G. B. Simpson   +5 more
wiley   +1 more source