Results 31 to 40 of about 11,204 (214)

Serine proteases profiles of Leishmania (Viannia) braziliensis clinical isolates with distinct susceptibilities to antimony. [PDF]

Sci Rep, 2021
Glucantime (SbV) is the first-line treatment against American Tegumentary Leishmaniasis. Resistance cases to this drug have been reported and related to host characteristics and parasite phenotypes.
Zabala-Peñafiel A, Dias-Lopes G, Cysne-Finkelstein L, Conceição-Silva F, Miranda LFC, Fagundes A, Schubach AO, Fernandes Pimentel MI, Souza-Silva F, Machado LA, Alves CR.   +10 more
europepmc   +2 more sources

A Cytokine Network Balance Influences the Fate of Leishmania (Viannia) braziliensis Infection in a Cutaneous Leishmaniasis Hamster Model. [PDF]

Front Immunol, 2021
The golden hamster is a suitable model for studying cutaneous leishmaniasis (CL) due to Leishmania (Viannia) braziliensis. Immunopathological mechanismsare wellstablished inthe L.
Paiva MB, Ribeiro-Romão RP, Resende-Vieira L, Braga-Gomes T, Oliveira MP, Saavedra AF, Silva-Couto L, Albuquerque HG, Moreira OC, Pinto EF, Da-Cruz AM, Gomes-Silva A.   +11 more
europepmc   +2 more sources

High performance of an enzyme linked immunosorbent assay for American tegumentary leishmaniasis diagnosis with Leishmania (Viannia) braziliensis amastigotes membrane crude antigens. [PDF]

PLoS One, 2020
The diagnosis of American tegumentary leishmaniasis (ATL) still requires the design of more effective tools. Leishmania (Viannia) braziliensis is the causal agent of the 90% of Argentinean ATL cases.
Bracamonte ME, Álvarez AM, Sosa AM, Hoyos CL, Lauthier JJ, Cajal SP, Juarez M, Uncos RE, Sánchez-Valdéz FJ, Acuña L, Diosque P, Basombrío MA, Nasser JR, Hashiguchi Y, Korenaga M, Barroso PA, Marco JD.   +16 more
europepmc   +2 more sources

Leishmania (Viannia) braziliensis type 2 as probable etiological agent of canine cutaneous leishmaniasis in Brazilian Amazon. [PDF]

PLoS ONE, 2019
Canine cutaneous leishmaniasis (CCL) is a zoonosis of public health interest, and in the Americas, Leishmania (Viannia) braziliensis has been identified as the main etiological agent. The present study sought to investigate Leishmania spp.
Andreia Fernandes Brilhante, Luciana Lima, Ricardo Andrade Zampieri, Vânia Lúcia Brandão Nunes, Maria Elizabeth Cavalheiros Dorval, Patrícia Fernandes Nunes da Silva Malavazi, Leonardo Augusto Kohara Melchior, Edna Aoba Yassui Ishikawa, Cristiane de Oliveira Cardoso, Lucile Maria Floeter-Winter, Marta Maria Geraldes Teixeira, Eunice Aparecida Bianchi Galati   +11 more
doaj   +2 more sources

Ecological Perspectives on Leishmaniasis Parasitism Patterns: Evidence of Possible Alternative Vectors for <i>Leishmania</i> (<i>Leishmania</i>) <i>infantum</i> (syn. <i>L. chagasi</i>) and <i>Leishmania</i> (<i>Viannia</i>) <i>braziliensis</i> in Piauí, Brazil. [PDF]

Pathogens
Leishmaniasis is difficult to control due to clinical and vector diversity associated with the complex life cycle of Leishmania parasites, which are transmitted by sandflies.
de Sousa RLT, Araujo-Pereira T, Vasconcelos SA, Freire SM, Lima OB, Dos Santos-Mallet JR, Vilela ML, Vasconcelos VMS, de Andrade EB, Gomes R, Teixeira C, Carvalho BM, Pita-Pereira D, Britto C.   +13 more
europepmc   +2 more sources

Big is not better: Comparing two alpha-Gal-bearing glycotopes in neoglycoproteins as biomarkers for Leishmania (Viannia) braziliensis infection. [PDF]

Carbohydr Res, 2023
Montoya AL, Gil ER, Vinales I, Estevao IL, Taboada P, Torrico MC, Torrico F, Marco JD, Almeida IC, Michael K.   +9 more
europepmc   +2 more sources

Antimony resistance in Leishmania (Viannia) braziliensis clinical isolates from atypical lesions associates with increased ARM56/ARM58 transcripts and reduced drug uptake. [PDF]

Mem Inst Oswaldo Cruz, 2019
BACKGROUND In addition to the limited therapeutic arsenal and the side effects of antileishmanial agents, drug resistance hinders disease control. In Brazil, Leishmania braziliensis causes atypical (AT) tegumentary leishmaniasis lesions, frequently ...
Rugani JN, Gontijo CMF, Frézard F, Soares RP, Monte-Neto RLD.   +4 more
europepmc   +2 more sources

Heterologous expression and biochemical characterization of the recombinant nucleoside triphosphate diphosphohydrolase 2 (LbNTPDase2) from Leishmania (Viannia) braziliensis. [PDF]

Purinergic Signal, 2023
da Rocha Torres Pavione N, de Moraes JVB, Ribeiro IC, de Castro RB, da Silva W, de Souza ACA, da Silva VHF, de Souza Vasconcellos R, da Costa Bressan G, Fietto JLR.   +9 more
europepmc   +2 more sources

In vitro inhibitory effect of chlorinated tetrasulfonated aluminum phthalocyanine against Leishmania (Viannia) Peruviana and Leishmania (Viannia) Braziliensis

Revista Peruana de Medicina Experimental y Salud Pública, 2020
Objectives: To evaluate the in vitro photodynamic activity of aluminum phthalocyanine tetrasulfonate chloride (AlPc- ClS4) on promastigotes and amastigotes of Leishmania (Viannia) peruviana and Leishmania (Viannia) braziliensis.
Kelly Vanesa Izarra-Rojas, Nyshon Rojas-Palomino, José Luis Gonzáles-Medrano, Gloria Minaya-Gómez, Alfredo Berrocal-Huallpa, Julio Santiago-Contreras, Jorge León-Quispe   +6 more
doaj   +2 more sources

Investigation of the pathways related to intrinsic miltefosine tolerance in Leishmania (Viannia) braziliensis clinical isolates reveals differences in drug uptake. [PDF]

Int J Parasitol Drugs Drug Resist, 2019
In Brazil, cutaneous leishmaniasis is caused predominantly by L. (V.) braziliensis. The few therapeutic drugs available exhibit several limitations, mainly related to drug toxicity and reduced efficacy in some regions.
Espada CR, Magalhães RM, Cruz MC, Machado PR, Schriefer A, Carvalho EM, Hornillos V, Alves JM, Cruz AK, Coelho AC, Uliana SRB.   +10 more
europepmc   +3 more sources