Results 71 to 80 of about 180,299 (231)

Exploring Aspartate Transcarbamoylase: A Promising Broad‐Spectrum Target for Drug Development

open access: yesChemBioChem, Volume 26, Issue 7, April 1, 2025.
Pyrimidine biosynthesis is a pivotal process shared by both eukaryotes and prokaryotes. This review examines the applications and advantages of a series of inhibitors specifically designed to target aspartate transcarbamylase within the de novo biosynthetic pathway of the malarial parasite.
Siyao Chen   +8 more
wiley   +1 more source

Microscopy and Polymerase Chain Reaction Detection of Leishmania chagasi in the Pleural and Ascitic Fluid of a Patient with AIDS: Case Report and Review of Diagnosis and Therapy of Visceral Leishmaniasis

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2004
Atypical visceral leishmaniasis is increasingly reported in immunocompromised patients, including patients with AIDS. A case of visceral leishmaniasis in an HIV-infected Brazilian patient with pulmonary and peritoneal involvement is reported ...
Ada RS Diehl   +6 more
doaj   +1 more source

Human leishmaniasis vaccines: Use cases, target population and potential global demand.

open access: yesPLoS Neglected Tropical Diseases, 2021
The development of vaccines against one or all forms of human leishmaniasis remains hampered by a paucity of investment, at least in part resulting from the lack of well-evidenced and agreed estimates of vaccine demand.
Stefano Malvolti   +4 more
doaj   +1 more source

A Longstanding Case of Black Grain Mycetoma in a Somalian Male Patient: A Case Report

open access: yesClinical Case Reports, Volume 13, Issue 4, April 2025.
ABSTRACT Mycetoma is a chronic granulomatous infection predominantly affecting young individuals, characterized by painless swelling and often misdiagnosed due to its resemblance to other conditions. This case report presents the first documented instance of eumycetoma located in the buttock of a 44‐year‐old male patient from Somalia, a region with ...
Mohamed Adam Mahamud   +6 more
wiley   +1 more source

Leishmaniasis visceral canina

open access: yesRevista MVZ Córdoba, 2000
La leishmaniasis visceral canina (LVC), producida por Leishmania infantum (=Leishmania chagasi) es una patología infecciosa zoonótica de importancia para la salud pública en países del Nuevo y Viejo Mundo. En Colombia se la encuentra distribuida en varios focos donde predomina el bosque seco tropical (Corredor et al., 1989).
openaire   +5 more sources

A case report on para-kala-azar dermal leishmaniasis: an unresolved mystery

open access: yesBMC Infectious Diseases, 2023
Background Post-kala-azar dermal leishmaniasis (PKDL) is a dermatosis that occurs 2–3 years after an apparently successful treatment of visceral leishmaniasis (VL).
Md. Mehedi Hasan   +6 more
doaj   +1 more source

Clinical and Immunopathological Aspects of Cutaneous, Mucocutaneous, Visceral, and Post-kala-azar Leishmaniasis

open access: yesJournal of Zoonotic Diseases, 2023
The disease Leishmaniasis is a neglected illness with two major forms clinically including cutaneous leishmaniasis and visceral leishmaniasis. From almost 100 endemic countries, an estimated one million additional records of leishmaniasis each year are
Basim Saleem Ahmed Al Sulivany   +1 more
doaj   +1 more source

A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH

open access: yesPLoS Neglected Tropical Diseases, 2017
Background Visceral leishmaniasis (VL or kala azar) is the most serious form of human leishmaniasis, responsible for over 20,000 deaths annually, and post kala azar dermal leishmaniasis (PKDL) is a stigmatizing skin condition that often occurs in ...
Mohamed Osman   +14 more
semanticscholar   +1 more source

Identification, Detection, and the Enhanced Removal Mechanism of DDT From Aqueous Solutions Using Facile Green Synthesis of Carbon Quantum Dots

open access: yesEngineering Reports, Volume 7, Issue 4, April 2025.
Removal of DDT from Aqueous solution using Carbon Quantum Dots. ABSTRACT Dichlorodiphenyltrichloroethane (DDT) pollution is an ongoing worldwide environmental hazard due to its persistence and detrimental impact on ecosystems. Carbon quantum dots (CQD) made from dried mushroom biomass using a sustainable and eco‐friendly synthesis process are ...
Sathish Sundararaman   +7 more
wiley   +1 more source

Kidney involvement in leishmaniasis—a review

open access: yesBrazilian Journal of Infectious Diseases, 2014
Leishmaniasis is an infectious disease caused by protozoa of the genus Leishmania transmitted by insects of the genus Lutzomyia sp. or Phlebotomus sp.
Geraldo Bezerra da Silva Junior   +2 more
doaj  

Home - About - Disclaimer - Privacy