Results 101 to 110 of about 109,637 (271)

Real-time PCR applications for diagnosis of leishmaniasis

Parasites & Vectors, 2018
Leishmaniasis is a vector-borne disease caused by many Leishmania species, which can infect both humans and other mammals. Leishmaniasis is a complex disease, with heterogeneous clinical manifestations ranging from asymptomatic infections to lesions at ...
L. Galluzzi, Marcello Ceccarelli, A. Diotallevi, M. Menotta, M. Magnani   +4 more
semanticscholar   +1 more source

Ultrastructural expansion microscopy reveals unexpected levels of glycosome heterogeneity in African trypanosomes

Journal of Microscopy, EarlyView.
Abstract Kinetoplastid parasites include several species. Trypanosoma brucei causes African sleeping sickness in humans and a wasting disease nagana in livestock. Trypanosoma cruzi is the causative agent of Chagas disease and Leishmania species cause leishmaniasis, which can present with visceral, cutaneous, or mucocutaneous symptoms.
Heidi Anderson, Rhonda Reigers Powell, Meredith Teilhet Morris   +2 more
wiley   +1 more source

The emergence of anthroponotic cutaneous leishmaniasis following the earthquake in southern villages of bam district, southeastern iran, 2010.

Journal of Arthropod-Borne Diseases, 2013
Background: The objective of this study was to assess the epidemiological characteristics of a new emerging focus of cutaneous leishmaniasis (CL) in southern villages of Bam District, southeastern Iran, 2010.
Mohammad Reza Aflatoonian, Iraj Sharifi, Somayeh Poursmaelian, Maryam Hakimi-Parizi, Nasser Ziaali   +4 more
doaj  

Canine Leishmaniasis Control in the Context of One Health

Emerging Infectious Diseases, 2019
Dogs are the main reservoir of Leishmania infantum and in some countries have been regularly culled as part of government policy to control visceral leishmaniasis.
F. Dantas‑Torres, G. Miró, G. Baneth, P. Bourdeau, E. Breitschwerdt, G. Capelli, L. Cardoso, M. Day, G. Dobler, L. Ferrer, P. Irwin, F. Jongejan, V. Kempf, B. Kohn, M. Lappin, S. Little, M. Madder, R. Maggi, C. Maia, M. Marcondes, T. Naucke, G. Oliva, M. Pennisi, B. Penzhorn, A. Peregrine, M. Pfeffer, X. Roura, Á. Sainz, SungShik Shin, L. Solano-Gallego, R. Straubinger, S. Tasker, R. Traub, I. Wright, D. Bowman, L. Gradoni, D. Otranto   +36 more
semanticscholar   +1 more source

Automated identification of spotted‐fever tick vectors using convolutional neural networks

Medical and Veterinary Entomology, EarlyView.
We evaluate the performance of convolutional neural networks (CNN) AlexNet, ResNet‐50 and MobileNetV2 for the automated identification of tick species capable of transmitting spotted fever. CNNs achieved accuracy rates of ~90% in identifying ticks and showed sensitivities of 59%–100% according to species, sex, position or image resolution.
Isadora R. C. Gomes, Vinícius L. Miranda, José Fabrício C. Leal, Igor P. Oliveira, Paula J. Silva, Karla Bitencourth, Claudio M. Rodrigues, Liege R. Siqueira, Marcelo B. Labruna, Gilberto S. Gazeta, Marinete Amorim, Rodrigo Gurgel‐Gonçalves   +11 more
wiley   +1 more source

Level of Knowledge and Risk Factors for Visceral Leishmaniasis in a Mining Area of Minas Gerais State, Brazil

Interdisciplinary Perspectives on Infectious Diseases, 2020
Aiming to optimize and adjust leishmaniasis prevention and control measures for the resident population of Pains, state of Minas Gerais, Brazil, a structured questionnaire containing conceptual questions and questions about household characteristics was ...
Carina Margonari, Júlia Alves Menezes, Gustavo Mayr de Lima Carvalho, Júlia Bahia Miranda, Fabrizio Furtado de Sousa, Felipe Dutra Rêgo, Aldenise Martins Campos, Carolina Cunha Monteiro, Ana Paula Madureira, José Dilermando Andrade Filho   +9 more
doaj   +1 more source

Leishmaniasis in humans: drug or vaccine therapy?

Drug Design, Development and Therapy, 2017
Leishmania is an obligate intracellular pathogen that invades phagocytic host cells. Approximately 30 different species of Phlebotomine sand flies can transmit this parasite either anthroponotically or zoonotically through their bites.
M. Ghorbani, R. Farhoudi
semanticscholar   +1 more source

Developing giant plasma membrane vesicles from Leishmania cells to investigate the role of membrane proteins in photodynamic inactivation

Photochemistry and Photobiology, EarlyView.
In this study, we developed giant plasma membrane vesicles (GPMVs) from Leishmania amazonensis promastigote membranes to investigate the role of protein‐embedded membranes in methylene blue (MB) photooxidation. Upon MB photoactivation in model lipid membranes (giant unilamellar vesicles, GUVs), a distinct photooxidation effect was observed, marked by ...
Maressa D. F. de Souza, Pietro Ciancaglini, Rosangela Itri, Martha S. Ribeiro   +3 more
wiley   +1 more source

Causes of Pediatric Visceral Leishmaniasis in Southeastern Iran

Iranian Journal of Parasitology, 2014
Leishmania infantum is the most frequent cause of visceral leishmaniasis and L. tropica has been rarely linked to the disease in Iran. In this study, bone marrow aspirates were collected from 10 child patients, suspected with visceral leishmaniasis ...
Ali Hosseininasab, Iraj Sharifi, Mohammad Hossein Daei, Mehdi Zarean, Mahsa Dadkhah   +4 more
doaj  

Leptin enhances the efficacy of glucantime to modulate macrophage polarization toward the M1 phenotype in Leishmania tropica-infected macrophages

Parasites & Vectors
Background Macrophages are essential immune cells during Leishmania infection, as their polarization toward M1/M2 phenotypes determines disease outcome.
Alireza Keyhani, Abdollah Jafarzadeh, Iraj Sharifi, Ehsan Salarkia   +3 more
doaj   +1 more source