Results 61 to 70 of about 171,841 (309)

Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles

Chemistry &Biodiversity, EarlyView.
The study obtained biopolymeric nanoparticles containing carvacrol (NPCar) and evaluated their anti‐leishmanial activity. NPCar obtained presented physicochemical characteristics due to its ideal nanometric size and zeta potential, and low polydispersity index.
Joyce Cordeiro Borges, Anne Beatriz Cunha Barros, Leonardo Lima Cardoso, Tatjana de Lima Souza Keesen, Luís André de Almeida Campos, Isabella Macário Ferro Cavalcanti, Elisângela Afonso de Moura Kretzschmar   +6 more
wiley   +1 more source

Management of trypanosomiasis and leishmaniasis [PDF]

, 2012
<p>Background: The current treatments for human African trypanosomiasis (HAT), Chagas disease and leishmaniasis (collectively referred to as the kinetoplastid diseases) are far from ideal but, for some, there has been significant recent progress ...
Alsford, Alvar, Alvar, Barrett, Barrett, Ben Salah, Berman, Bern, Brun, Brun, Burri, Chappuis, Coura, Croft, Croft, El-Sayed, Frearson, Hailu, Jacobs, Jacobs, Le Loup, Lessa, M. P. Barrett, Miranda-Verastegui, Paine, Pinazo, Priotto, Rassi, Reithinger, Rodgers, S. L. Croft, Stuart, Sundar, Sundar, Sundar, Sundar, Torreele, Vanhollebeke, Vincent, Voogd   +39 more
core   +2 more sources

The synergistic anti-leishmanial effect of photodynamic therapy employing chemotherapy-mediated nanocomposites

Scientific Reports
Cutaneous leishmaniasis (CL) presents a significant therapeutic challenge due to limitations of current treatments like meglumine antimoniate (MAT), including drug resistance and adverse side effects. Photodynamic therapy (PDT) has emerged as a promising,
Elahe Molaakbari, Ahmad Khosravi, Ehsan Salarkia, Iraj Sharifi, Alireza Keyhani, Mehdi Bamorovat, Mohammad Zarif, Fatemeh Sharifi   +7 more
doaj   +1 more source

Risk factors for visceral leishmaniasis in a new epidemic site in Amhara Region, Ethiopia [PDF]

, 2009
We conducted a case-control study to evaluate risk factors for visceral leishmaniasis during an epidemic in a previously unaffected district of Ethiopia. We also collected blood and bone marrow specimens from dogs in the outbreak villages.
Alvar, Jorge, Aparicio, Pilar, Argaw, Daniel, Bashaye, Seife, Bern, Caryn, Cañavate, Carmen, Chicharro, Carmen, Herrero, Merce, Mulugeta, Abate, Nieto, Javier, Nombela, Nohelly, Vélez, Iván Darío   +11 more
core   +1 more source

Liposomal amphotericin B for visceral leishmaniasis in human immunodeficiency virus-coinfected patients: 2-year treatment outcomes in Bihar, India [PDF]

, 2011
Reports on treatment outcomes of visceral leishmaniasis (VL)-human immunodeficiency virus (HIV) coinfection in India are lacking. To our knowledge, none have studied the efficacy of liposomal amphotericin B in VL-HIV coinfection.
Alvar, Bachani, Berman, Bern, Bora, Braitstein, C. Ferreyra, D. Remartinez, G. Mitra, Hurissa, Ikomi, J. van Griensven, K. Pandey, L. Flevaud, Lin, Lyons, M. Pece, Mathur, N. Kumar, N. Verma, P. Das, P. K. Sinha, P. Kumar, P. P. Palma, Pintado, R. Kumar, R. Mahajan, Redhu, Sinha, Sinha, Sundar, Sundar, ter Horst, Thakur, van Griensven   +34 more
core   +2 more sources

Efficient and Rapid Arylation of NH₂‐Unprotected Bromobisindole Ethanamines via Suzuki‐Miyaura Coupling: Generating New Leads Against Leishmania

Chemistry – A European Journal, EarlyView.
A library of novel bisindole derivatives was synthesized through an optimized rapid Suzuki‐Miyaura coupling reaction, utilizing NH2‐unprotected bromobisindole ethanamines and boronic acids with yields up to 93%. The compounds were screened for their activity against L. infantum promastigotes.
Alessandro Buono, Aurora Diotallevi, Sara Maestrini, Michele Verboni, Paula Kiuru, Luca Galluzzi, Andrea Duranti, Diego Olivieri, Simone Lucarini   +8 more
wiley   +1 more source

Pregnancy‐triggered pemphigus vulgaris with favorable fetal outcomes: A case report

Clinical Case Reports, 2022
Pemphigus vulgaris is an autoimmune bullous dermatosis which if occurred during pregnancy may result in neonatal complications. In this study we report a 41 years old woman with pemphigus vulgaris that triggered by pregnancy in first trimester of ...
Fatemeh Mohaghegh, Zabihollah Shahmoradi, ‬Maryam Alizadeh   +2 more
doaj   +1 more source

Uniting mathematics and biology for control of visceral leishmaniasis [PDF]

, 2015
The neglected tropical disease (NTD) visceral leishmaniasis (VL) has been targeted by the WHO for elimination as a public health problem on the Indian subcontinent by 2017 or earlier.
Adams, ER, De Vlas, SJ, Hollingsworth, TD, Le Rutte, EA, Medley, GF, Rock, KS   +5 more
core   +2 more sources

Antiprotozoal Activity of Highly Substituted Pyrazole and Pyrimidine Derivatives

ChemMedChem, EarlyView.
Based on previously identified antimalarial agents, a series of highly substituted pyrazole and pyrimidines derivatives has been synthesized and tested for antiplasmodial and antileishmanial activity. Selected derivatives show promising antiplasmodial effect with a predicted favorable pharmacokinetic profile.
Matteo Lusardi, Nicoletta Basilico, Erika Iervasi, Chiara Brullo, Silvia Parapini, Marco Ponassi, Camillo Rosano, Andrea Spallarossa   +7 more
wiley   +1 more source

Use of Natural Products in Leishmaniasis Chemotherapy: An Overview

Frontiers in Chemistry, 2020
Leishmaniasis is an infectious parasitic disease that is caused by protozoa of the genus Leishmania, a member of the Trypanosomatidae family. Leishmaniasis is classified by the World Health Organization as a neglected tropical disease that is responsible
Luiza F O Gervazoni, Gabrielle Barcellos, Taiana Ferreira-Paes, E. E. Almeida-Amaral   +3 more
semanticscholar   +1 more source