Results 51 to 60 of about 6,804,949 (307)

ZNF827 is a single-stranded DNA binding protein that regulates the ATR-CHK1 DNA damage response pathway

Nature Communications
The ATR-CHK1 DNA damage response pathway becomes activated by the exposure of RPA-coated single-stranded DNA (ssDNA) that forms as an intermediate during DNA damage and repair, and as a part of the replication stress response. Here, we identify ZNF827 as
Sile F. Yang, Christopher B. Nelson, Jadon K. Wells, Madushan Fernando, Robert Lu, Joshua A. M. Allen, Lisa Malloy, Noa Lamm, Vincent J. Murphy, Joel P. Mackay, Andrew J. Deans, Anthony J. Cesare, Alexander P. Sobinoff, Hilda A. Pickett   +13 more
doaj   +1 more source

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A cadaveric study of human spleen and its clinical significance

National Journal of Clinical Anatomy, 2017
Background & Aim: Spleen is an important lymphatic organ that is connected to the blood vascular system. It is important component of the reticuloendothelial system.
Subhash M Gujar, Sunil G Oza, Jaidevsingh Shekhawat   +2 more
doaj   +1 more source

Characteristics of the length of the radius and ulna in children

Frontiers in Pediatrics, 2022
ObjectivesCongenital malformation, trauma, tumor, or metabolic disease can cause length deformity of the radius or ulna, affecting the appearance and function of the forearm.
Chunxing Wu, Dahui Wang, Yueqiang Mo, Zhiqiang Zhang, Bo Ning   +4 more
doaj   +1 more source

Newborn telomere length predicts later life telomere length: Tracking telomere length from birth to child- and adulthood.

EBioMedicine, 2021
BACKGROUND Telomere length (TL) is considered a biological marker of aging and may indicate age-related disease susceptibility. Adults and children show a fixed ranking and tracking of TL over time.
D. Martens, Charlotte Van Der Stukken, C. Derom, E. Thiery, E. Bijnens, T. Nawrot   +5 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Kemik İliği Biyopsilerinin Yeterlilik ve Kalitesinin Tanı Sürecine Etkileri

Hitit Medical Journal, 2022
Amaç: Kemik iliği kor biyopsileri, kemik iliğinin hücresel özelliklerini, solid organ tümörü metastazlarını veya hematolojik malign tutulumlarını belirlemek için yapılan önemli incelemelerdir. Kor biyopsinin uzunluğu ve kalitesi doğru tanı konulmasını ve
Merve Çırak Balta, Füruzan Kacar, İrfan Yavaş   +2 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Technical condition features of the forest ways in the Ukrainian Carpathians

Наукові праці Лісівничої академії наук України, 2021
The article presents the results of studies of the forest transport infrastruc-ture used for hauling timber, which is harvested in forest areas located on the northeastern mega-slope of the Ukrainian Carpathians. The research was carried out at two state-
Volodymyr Korzhov
doaj   +1 more source