Results 251 to 260 of about 202,804 (290)

A new approach for Small Ruminant Lentivirus full genome characterization revealed the circulation of divergent strains

, 2019
Barbara Colitti, Elisabetta Coradduzza, Giantonella Puggioni, Maria Teresa Capucchio, Ramsés Reina, Luigi Bertolotti, Sergio Rosati   +6 more
openalex   +1 more source

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

Advanced Science, EarlyView.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen, Fanli Qu, Long Wang, Qing Shao, Sisi Li, Yang Qin, Dongping Jiang, Senmiao Zhang, Jiangdong Sui, Guanwen Wang, Ningning Zhang, Xiaohua Zeng   +11 more
wiley   +1 more source

MMP14-Dependent Activation of TGF-β Signaling Enhances Malignancies via Promoting Necroptosis in Glioblastoma. [PDF]

FASEB J
Zhou H, Wu W, Cao Y, Zhang B, Zhou M, Wang Y, Wang M, Wang J.   +7 more
europepmc   +1 more source

Increase of C1q biosynthesis in brain microglia and macrophages during lentivirus infection in the rhesus macaque is sensitive to antiretroviral treatment with 6-chloro-2′,3′-dideoxyguanosine

, 2005
Candan Depboylu, Michael Schäfer, Wilhelm Schwaeble, Todd A. Reinhart, Hiroshi Maeda, Hiroaki Mitsuya, Ruslan Damadzic, Dianne M. Rausch, Lee E. Eiden, Eberhard Weihe   +9 more
openalex   +2 more sources

TrxR2 Lactylation Facilitates Mitochondrial Protection and Endothelial Ferroptosis Resistance in Diabetic Cardiomyopathy

Advanced Science, EarlyView.
TrxR2 deletion in diabetic mice suppresses TUFM‐AMPK‐FUNDC1‐dependent mitophagy in endothelial cells, resulting in SCP2 upregulation and mitochondrial translocation of ACSL4. Mitochondrial ACSL4 promotes mitochondrial eicosanoid biosynthesis and ferroptosis, thereby aggravating cardiac microvascular injury and diabetic cardiomyopathy.
Su Li, Muyin Liu, Chao Chen, Xinyan Li, Xiaopei Yan, Wentao Zhu, Wenyan Qiu, Qiyu Li, Xiangyu Sun, Chao Huang, Ming Yin, Zhangwei Chen, Yao Lu, Junbo Ge, Xiangqing Kong, Juying Qian, Yuqiong Chen   +16 more
wiley   +1 more source

Yes-associated protein regulates autophagy to restore skin barrier function in atopic dermatitis. [PDF]

Front Immunol
Jia J, Ma X, Wang T, Ye S, Yan F, Liu J, Li H, Chen D, Mo X.   +8 more
europepmc   +1 more source

Influence on the malignant phenotype of renal cell carcinoma caused by the ectogenesis of p27kip1 induced by lentivirus.

, 2010
Peng Wu, Shao-bin Zheng, Wanlong Tan, Qianming Chen   +3 more
openalex   +1 more source

Sensing and Reprogramming Surface Receptor Activation With Synthetic Transcriptional Circuits

Advanced Science, EarlyView.
A synthetic receptor‐signalling induced transcription (RESIT) circuit is designed based on receptor activation mediated split protease complementation and release of membrane‐tethered synthetic transcriptional modules. The RESIT system enables probing Ca2+ entry, receptor tyrosine kinase (RTK) activities and Ras activation, and reprogramming RTK ...
Fei Liu, Mei Yuan, Li‐Juan Tang, Fenglin Wang, Xia Chu, Jian‐Hui Jiang   +5 more
wiley   +1 more source

LPAR1 Promotes Activation of Pathways Alveolar Hypercoagulation and Fibrinolytic Inhibition in ARDS via NF-κB Signaling Pathway. [PDF]

FASEB Bioadv
Liu Y, Chen X, Liu M, Yuan J, Li Q, Li L, Dong Q, Tao J, Shen F, Xiao C.   +9 more
europepmc   +1 more source

[Lentivirus-mediated stable silencing of nm23-H1 gene in lung cancer cells and the influence on biological behavior].

, 2012
Meng Luo, Daxing Zhu, Lei Gong, Xiaoming Qiu, Lingling Zu, Liya Sun, Zhihao Wu, Qinghua Zhou   +7 more
openalex   +2 more sources