Results 41 to 50 of about 98,106 (307)

In Vivo Impairment of Neutrophil Recruitment during Lentivirus Infection [PDF]

open access: yesThe Journal of Immunology, 2003
Abstract Evidence indicates that the lentivirus, HIV, infection affects neutrophil response to bacteria and bacterial products in vitro. We used a novel model of rapid onset immunosuppression following infection with a similar lentivirus, feline immunodeficiency virus (FIV), in cats to examine neutrophil function within the ...
Paul, Kubes   +6 more
openaire   +2 more sources

Multiplex interrogation of the NK cell signalome reveals global downregulation of CD16 signaling during lentivirus infection through an IL-18/ADAM17-dependent mechanism.

open access: yesPLoS Pathogens, 2023
Despite their importance, natural killer (NK) cell responses are frequently dysfunctional during human immunodeficiency virus-1 (HIV-1) and simian immunodeficiency virus (SIV) infections, even irrespective of antiretroviral therapies, with poorly ...
Sho Sugawara   +10 more
doaj   +1 more source

Genome editing technologies to fight infectious diseases [PDF]

open access: yes, 2017
Genome editing by programmable nucleases represents a promising tool that could be exploited to develop new therapeutic strategies to fight infectious diseases.
Barzon, Luisa   +2 more
core   +1 more source

Occurrence of Puma Lentivirus Infection in Cougars from Washington [PDF]

open access: yesJournal of Wildlife Diseases, 1997
Puma lentivirus (PLV) antibodies were detected in 13 (25%) of 52 serum samples obtained from cougars (Felis concolor) collected by hunters. The serum samples were collected from November 1993 through January 1994 from four specific regions throughout the state of Washington (USA), and included the Olympic Mountains, the Cascade Mountains, the Blue ...
Evermann, James F   +3 more
openaire   +3 more sources

Salmonella produce microRNA-like RNA fragment Sal-1 in the infected cells to facilitate intracellular survival. [PDF]

open access: yes, 2017
Salmonella have developed a sophisticated machinery to evade immune clearance and promote survival in the infected cells. Previous studies were mostly focused on either bacteria itself or host cells, the interaction mechanism of host-pathogen awaits ...
Chen, Xi   +11 more
core   +2 more sources

Use of recombinant lentivirus pseudotyped with vesicular stomatitis virus glycoprotein G for efficient generation of human anti-cancer chimeric T cells by transduction of human peripheral blood lymphocytes in vitro

open access: yesVirology Journal, 2006
Background Genetic redirection of lymphocytes that have been genetically engineered to recognize antigens other than those originally programmed in their germlines is a potentially powerful tool for immunotherapy of cancers and potentially also of ...
Kolokoltsov Andrey A   +3 more
doaj   +1 more source

Viral-induced neurodegenerative disease. [PDF]

open access: yes, 1999
Viral etiology has been postulated in a variety of neurological diseases in humans, including multiple sclerosis. Several experimental animal models of viral-induced neurodegenerative disease provide insight into potential host- and pathogen-dependent ...
Buchmeier, MJ, Lane, TE
core   +1 more source

Infection of Dendritic Cells by the Maedi-Visna Lentivirus [PDF]

open access: yesJournal of Virology, 2000
ABSTRACTThe early stages of lentivirus infection of dendritic cells have been studied in an in vivo model. Maedi-visna virus (MVV) is a natural pathogen of sheep with a tropism for macrophages, but the infection of dendritic cells has not been proven, largely because of the difficulties of definitively distinguishing the two cell types.
S, Ryan   +3 more
openaire   +2 more sources

Hepatitis B virus inhibition in mice by lentiviral vector mediated short hairpin RNA

open access: yesBMC Gastroenterology, 2009
Background Chronic hepatitis B virus (HBV) infection is an important cause of cirrhosis and hepatocellular carcinoma. The major challenges for current therapies are the low efficacy of current drugs and the occurrence of drug resistant HBV mutations. RNA
Wang Xuehao   +7 more
doaj   +1 more source

Surfactants as microbicides and contraceptive agents: a systematic in vitro study. [PDF]

open access: yesPLoS ONE, 2008
BACKGROUND: The urgent need for cheap and easy-to-use protection against both unwanted pregnancies and sexually transmitted diseases has stimulated considerable interest in the use of surfactants as microbicides, anti-viral, and contraceptive agents in ...
Otilia V Vieira   +8 more
doaj   +1 more source

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