Results 81 to 90 of about 87,400 (287)

Small ruminants Lentivirus infection in the region of Trás-os-Montes, Portugal: preliminar results [PDF]

open access: yes, 2022
Small ruminant lentiviruses (SRLVS) are a group of viruses responsible for Maedi-Visna in ovine and for Caprine Arthritis Encephalitis in caprine species.
Jacob-Ferreira, João   +6 more
core   +1 more source

Initial lentivirus-host interactions within lymph nodes: a study of maedi-visna virus infection in sheep

open access: yes, 1995
Reactive changes occurring within lymph nodes draining the subcutaneous site of acute infection with maedi-visna virus (MVV) were studied, and the appearance of infected cells correlated with the immune response.
Hopkins, John   +7 more
core  

Protein Disulfide Isomerase Disassembles TDP‐43/G3BP1 Condensates and Antagonizes TDP‐43 Pathological Aggregates

open access: yesAdvanced Science, EarlyView.
Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu   +14 more
wiley   +1 more source

Use of small ruminant lentivirus-infected rams for artificial insemination

open access: yes, 2011
The presence of proviral DNA, mRNA transcripts and/or viral proteins in small ruminant lentiviral infections may be intermittent. The aim of this study was to identify methods of avoiding small ruminant lentivirus (SRLV) transmission to ewes when using ...
Beatriz Amorena   +19 more
core   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

An analysis of Bovine immunodeficiency virus and Jembrana disease virus infections in Bos javanicus

open access: yes, 2010
Two closely related bovine lentiviruses have been described, Jembrana disease virus (JDV) and Bovine immunodeficiency virus (BIV), that produce very different clinical manifestations in infected cattle.
McNab, Tegan Josephine
core  

Plasmids used for lentivirus production and subsequent mouse infections/Lentiviral vectors.

open access: yes, 2014
A) Schematic of a generalized two-plasmid LR recombination reaction between a generalize entry vector containing a cDNA and gLEX-iCL, a Gateway compatible lentivirus encoding Cre(T2A)Luc B) The resulting recombinant lentiviral expression vector when ...
Benjamin Geiling (469741)   +2 more
core   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang   +32 more
wiley   +1 more source

Evaluation of a recombinant p24 antigen for the detection of Feline Immunodeficiency Virus-specific antibodies Avaliação do antígeno recombinante p24 para a detecção de anticorpos específicos do Vírus da Imunodeficiência Felina

open access: yesPesquisa Veterinária Brasileira, 2010
Feline Immunodeficiency Virus is a worldwide infection and is considered a significant pathogen. The diagnosis of FIV infections is mainly based on commercially available rapid tests that are highly expensive in Brazil, hence it is rarely performed in ...
Carlos Mazur   +6 more
doaj   +1 more source

PRC2.1 Coordinates Peri‐Nucleolar H3K27me3‐Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar Integrity

open access: yesAdvanced Science, EarlyView.
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu   +12 more
wiley   +1 more source

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