Results 171 to 180 of about 62,168 (302)

Genotyping Based on the LTR Region of Small Ruminant Lentiviruses from Naturally Infected Sheep and Goats from Mexico [PDF]

, 2019
Wolfang P. S. Mendiola, Jorge Tórtora, H. Martinez, María M. García, Sandra Cuevas-Romero, José L. Cerriteño, Hugo Ramírez Álvarez   +6 more
openalex   +1 more source

The double life of lentiviruses [PDF]

Nature Methods, 2006
openaire   +2 more sources

Intercellular Horizontal Transfer of TXNDC5 mRNA via Extracellular Vesicles Contributes to Tumor‐Associated Macrophage‐Mediated Prostate Cancer Metastasis

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study investigates the role of M2 macrophage‐derived extracellular vesicles (M2 EVs) in prostate cancer (PCa) metastasis. Mechanistically, M2 EVs horizontally transfer TXNDC5 mRNA to PCa cells, where the molecule induces the mesenchymal‐like state (MLS), enhancing PCa migration and invasion.
Cong Hu, Tianyang Wu, Jiayi Wang, Xinxing Du, Xinrui Wu, Yanhao Dong, Zehong Peng, Penghui Liao, Zirui Guo, Zheyu Liu, Kenneth J Pienta, Yinjie Zhu, Jiahua Pan, Liang Dong, Wei Xue   +14 more
wiley   +1 more source

Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han, June‐Hyun Jeong, Dongjoon Lee, Yujin Jung, Yujin Jin, Eun Sun Jung, Haeng Jun Kim, Woo Youn Kim, Chang‐Han Lee, Inhee Mook‐Jung   +9 more
wiley   +1 more source

Targeting NME3 to Restore Mitochondrial Fission‐Fusion Balance Defines a Novel Disease‐Modifying Strategy for Parkinson's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
NME3 deficiency disrupts mitochondrial fission‐fusion balance, causing neuronal damage via ROS. Pharmacological Drp1 inhibition (Mdivi‐1) or substantia nigra‐specific NME3 overexpression restores mitochondrial equilibrium, prevents dopaminergic neuron loss, and alleviates motor deficits in PD models.
Chen Qiao, Xiang‐Qi Hu, Shen‐Han Xu, Meng‐Fan Yao, Jun‐Peng Liu, Lei Cao   +5 more
wiley   +1 more source

Construction of Cell-Type Specific Promoter Lentiviruses for Optically Guiding Electrophysiological Recordings and for Targeted Gene Delivery

, 2009
Aaron M. Jasnow, Donald G. Rainnie, Kimberly A. Maguschak, Jasmeer P. Chhatwal, Kerry J. Ressler   +4 more
openalex   +1 more source

Interspecific transmission of small ruminant lentiviruses from goats to sheep [PDF]

, 2015
T. S. de Souza, R. R. Pinheiro, Joselito Nunes Costa, Carla Caroline Valença de Lima, A. Andrioli, Dalva Alana Aragão de Azevedo, Vanderlan Warlington Souza dos Santos, Juscilânia Furtado Araújo, Ana Lídia Madeira de Sousa, Danielle Nobre Santos Pinheiro, Flora M.C. Fernandes, Antônio Oliveira Costa Neto   +11 more
openalex   +1 more source

GALNT3 Inhibits the Progression of Cerebral Ischemia–Reperfusion Injury by Stabilizing TREM2 via O‐GalNAc Glycosylation

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
The neuroprotective effect of GALNT3 against CIRI and the underlying mechanisms. GALNT3 directly interacts with and catalyzes the mucin‐type O‐GalNAcylation of TREM2 predominantly at serine 147, which enhances TREM2 protein stability. This GALNT3‐TREM2 axis suppresses the release of pro‐inflammatory cytokines, oxidative stress, and activation of M1 ...
Xinyi Fei, Jinghui Yang, Rui Zhang, Yu Zhang, Shan Yu   +4 more
wiley   +1 more source

Epidemiological survey in single-species flocks from Poland reveals expanded genetic and antigenic diversity of small ruminant lentiviruses

, 2018
Monika Olech, Stephen Valas, Jacek Kuźmak   +2 more
openalex   +2 more sources

Diphtheria Toxin A-Resistant Cell Lines Enable Robust Production and Evaluation of DTA-Encoding Lentiviruses [PDF]

, 2019
Margaret J. Lange, Terri D. Lyddon, Marc C. Johnson   +2 more
openalex   +1 more source