Results 161 to 170 of about 46,404 (214)
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Frontiers in Bioscience, 2003
Lentiviruses belong to a subfamily of the retroviruses usually associated with persistent infections in animals and humans. They have complex replication cycles involving numerous regulatory and accessory proteins, which sets them apart from the oncoretroviruses and spumaviruses, the two other main subfamilies of the retroviruses.
Edward, Acheampong +3 more
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Lentiviruses belong to a subfamily of the retroviruses usually associated with persistent infections in animals and humans. They have complex replication cycles involving numerous regulatory and accessory proteins, which sets them apart from the oncoretroviruses and spumaviruses, the two other main subfamilies of the retroviruses.
Edward, Acheampong +3 more
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Lentiviruses in Cancer Immunotherapy
Future Virology, 2007Lentiviral vectors have emerged as promising tools for cancer immunotherapy owing to their capacity to transduce a wide range of different cell types, including dendritic cells (DCs), the key regulators of immunity. Ex vivo transduced DCs proved to be potent inducers of strong antigen-specific T-cell responses, both in vitro and in vivo.
Breckpot, Karine, Thielemans, Kris
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Update on Small Ruminant Lentiviruses
Veterinary Clinics of North America: Food Animal Practice, 2021Small ruminant lentiviruses (SLRVs) have been recognized throughout the world for decades. SLRVs are a heterogenous group of viruses that can infect sheep, goats, and wild ruminants. Evidence supports cross-species infection. These viruses cause lifelong infections where they target specific organs, which can result in production losses due to ...
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The Nef protein of primate lentiviruses
Reviews in Medical Virology, 1999The Nef protein of primate lentiviruses acts as an important virulence factor in vivo both in monkeys and in humans. Among a human cohort of long-term non-progressors, several Nef defective HIV1 viruses have been isolated, indicating that Nef may accelerate HIV progression and disease in humans.
Piguet V, Trono D
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Transmission of small ruminant lentiviruses
Veterinary Microbiology, 2004Small ruminant lentiviruses (SRLV) are classical slow retroviruses causing chronic inflammatory disease in a variety of target organs. The routes of transmission have been investigated and a large body of evidence has accumulated over many years.
Blacklaws, Barbara +6 more
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Lentiviruses as gene delivery vectors
Current Opinion in Biotechnology, 1999Lentivirus vectors are already used as effective gene delivery tools in cells from liver, retina, skeletal muscle and the central nervous system. In the past year, new and exciting data from gene transfer experiments in human hematopoietic progenitor cells have been obtained. Furthermore, new generations of HIV-1 based lentivirus vectors as well as new
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Lentiviruses as Vectors for CNS Diseases
2002During the past decade, mutations implicated in familial forms of CNS diseases have been identified (MARTIN 1995). The subsequent development of transgenic mouse models (AGUZZI et al. 1996), the use of gene-chip technology (SERAFINI 1999) and the development of functional imaging (PICCINI et al.
Déglon N, Aebischer P
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1994
The bovine immunodeficiency virus (BIV) is a horizontally transmitted, nonon-cogenic, pathogenic retrovirus and member of the lentivirus genus (Fig. 1). It was discovered in the late 1960s during the intensive search for the cause of bovine leukemia/lymphosarcoma.
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The bovine immunodeficiency virus (BIV) is a horizontally transmitted, nonon-cogenic, pathogenic retrovirus and member of the lentivirus genus (Fig. 1). It was discovered in the late 1960s during the intensive search for the cause of bovine leukemia/lymphosarcoma.
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Diagnostic tests for small ruminant lentiviruses
Veterinary Microbiology, 2005Maedi visna virus and caprine arthritis encephalitis virus are closely related retroviruses that cause chronic inflammatory disease in small ruminants. The infections are characterised by insidious onset and slow progression. Diagnosis of infection is usually by serological testing.
Andrés, Damián F. de +6 more
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