Nanoparticle‐Mediated Therapy for Glioma: Advances and Prospects
MedComm – Oncology, Volume 5, Issue 3, September 2026.Various nanocarriers, including liposomes, dendrimers, exosomes and gold nanoparticles, are designed to penetrate the blood‐brain barrier and deliver chemotherapy, radiotherapy, immunotherapy, gene therapy, phototherapy, magnetic hyperthermia and sonodynamic therapy for glioma.
Wenqian Jiang +5 more
wiley +1 more source
Deciphering the STAT3-PXN positive feedback loop in GBM, IDH-wildtype: transcriptional regulation and inhibition of YB-1 ubiquitination. [PDF]
Cell Death DiscovLi X +6 more
europepmc +1 more source
Small Science, Volume 6, Issue 9, September 2026.A biomimetic 3D human skeletal muscle microtissue platform is developed by integrating primary young and aged SkMCs with muscle‐derived dECM and 3D‐printed PCL anchors. Aged constructs recapitulate selected biological and functional hallmarks of skeletal muscle aging, including impaired myotube formation, mitochondrial alterations, calcium handling ...
Sohae Yang +9 more
wiley +1 more source
Aging Cell, Volume 25, Issue 9, September 2026.Advanced maternal age impairs uterine decidualization via downregulated RICTOR‐ATK3‐FoxO1 signaling. The RICTOR agonist MHY1485 rescues decidual defects, offering a therapy for age‐related pregnancy failure. ABSTRACT Miscarriage and abnormal embryonic development in women of advanced maternal age (AMA) are often associated with impaired decidualization.
Yifeng Lin +9 more
wiley +1 more source
Discovery of a novel envelope protein derived from simian retrovirus 2 for pseudotyping retroviral vectors used for production of CAR immune cells. [PDF]
Nat CommunJeun M +5 more
europepmc +1 more source
Creb3l1 Overexpression Improves Flexor Tendon Repair in Aged Rats
Aging Cell, Volume 25, Issue 9, September 2026.Aging impairs flexor tendon repair, with aged tendons showing reduced Col1a1 and Sparc expression and compromised mechanical properties. The transcription factor Creb3l1 binds both gene promoters and drives their expression; its overexpression restores Col1a1 and Sparc levels and improves the gliding function, healing strength, and elastic modulus of ...
Qian Qian Yang +4 more
wiley +1 more source
Zinc finger TRAF-type containing 1 can promote the progression and metastasis of lung adenocarcinoma. [PDF]
CytojournalYu Y, Zhao Q, Song L.
europepmc +1 more source
Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling
Andrology, Volume 14, Issue 6, Page 1831-1846, September 2026.ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu +7 more
wiley +1 more source
CD25 genetic ablation on lymphoid cell lines to obtain models of stimulation through the Interleukin-2 beta/gamma receptor. [PDF]
Sci RepRelova-Hernández E +6 more
europepmc +1 more source
British Journal of Pharmacology, Volume 183, Issue 17, Page 5211-5229, September 2026.Background and Purpose The CKLF‐like MARVEL transmembrane domain containing superfamily (CMTM) has an important role in tumour immunity. The role of CMTM8 in tumour immune microenvironment (TIME) remains unknown. The aim was to investigate the relationship between CMTM8 and antitumour immunity. Experimental Approach Lentiviral system was established to
Fanglin Li +14 more
wiley +1 more source