Results 181 to 190 of about 62,168 (302)

Molecular Pharming: Advances, Applications, and Future Prospects in Biotechnology and Medicine

Engineering in Life Sciences, Volume 26, Issue 3, March 2026.
ABSTRACT Genetically engineered plants incorporate the use of a novel bioreactor known as molecular pharming, which has a transformative view on the pharmaceutical industry. The technique enables mass production, at a low cost, and reproducibly of a large number of different protein‐based drugs, vaccines, and industrial enzymes. This review‐based study
Md. Hridoy Ahmed, Md. Mustak Khan, Shishir Dutta, Md. Foyzur Rahman, Mohammad Shariful Islam, Md. Najmul Hosen, Md. Saad Hossain, Md. Aftabur Rahman, Md. Sadman Hasan Sahil, Tanjuma Tasnim Hira, Ifthesum, Ashikur Rahaman, Md. Afser Rabbi, Laila Khaleda   +13 more
wiley   +1 more source

Transferring mouse Emx1 and Emx2 lentiviruses into the chicken embryonic brain and their implication to the organization and evolution of the amniote pallium [PDF]

Rui Zhao, Yuanyuan Gao, Chao Xi, Yizhi Liu, Shiying Lin, Shan Zhen Lu, Jin Liu, Jie Bing, Xinwen Zhang, Shaoju Zeng   +9 more
openalex   +1 more source

Prostaglandin D2 Synthase Controls Schwann Cells Metabolism and Peripheral Myelin Homeostasis

Glia, Volume 74, Issue 3, March 2026.
Prostaglandin D2 Synthase (L‐PGDS) controls PPNS myelin lipids’ composition and Schwann cells energetic metabolism In the absence of L‐PGDS Schwann cells turn to acetate as the main energetic source. These metabolic changes result in ketone bodies production to preserve neuronal survival.
Amelia Trimarco, Matteo Audano, Rosa La Marca, Marta Pellegatta, Paolo Canevazzi, Mariaconcetta Cariello, Marta Falco, Silvia Pedretti, Gabriele Imperato, Alessandro Cestaro, Paola Podini, Giorgia Dina, Angelo Quattrini, Luca Massimino, Donatella Caruso, Nico Mitro, Carla Taveggia   +16 more
wiley   +1 more source

Development and Application of a Pseudovirus-Based Assay for Modelling SARS-CoV-2 Spike Protein Mediated Drug Screening. [PDF]

Int J Mol Sci
Khasanov SA, Esaulkova IL, Volobueva AS, Slita AV, Kriger DV, Tentler D, Yarovaya OI, Sokolova AS, Gorshkov AN, Dolgova AS, Lavrentieva IN, Dedkov VG, Salakhutdinov NF, Zarubaev VV.   +13 more
europepmc   +1 more source

The Susceptibility of Primate Lentiviruses to Nucleosides and Vpx during Infection of Dendritic Cells Is Regulated by CA [PDF]

, 2015
Véronique Barateau, Xuan-Nhi Nguyen, Fanny Bourguillault, Grégory Berger, Stéphanie Cordeil, Andrea Cimarelli   +5 more
openalex   +1 more source

Ginsenoside Rb1 Targets the HRD1‐STING Axis to Mitigate Cholesterol‐Induced VSMC Senescence

Journal of Clinical Laboratory Analysis, Volume 40, Issue 5, March 2026.
Schematic representation of the proposed mechanism of action for Ginsenoside Rb1. Suppression of HRD1 expression in VSMCs cholesterol stimulation, leading to ER stress (BiP/XBP1s upregulation), STING pathway activation, ROS accumulation (including mitochondrial ROS), and ultimately, VSMC senescence.
Haiming Niu, Yingzhang Cai, Conghui Yu, Ning Lin, Miaolian Chen, Linli Wang   +5 more
wiley   +1 more source

HnRPD/AUF1 facilitates human ovarian cancer progression through activating FLI1 and maintaining cisplatin resistance. [PDF]

Mol Cancer
Tang C, Zhu C, An Z, Cao B, Xu Q, Li L, Bao Y, Li J.   +7 more
europepmc   +1 more source

Immune Responses to Nonhuman Primate Lentiviruses

, 2001
Amitinder Kaur, Marie‐Claire Gauduin, R. Paul Johnson   +2 more
openalex   +1 more source

Development of a Live‐Cell Imaging Assay to Elucidate Spatiotemporal Dynamics of Extracellular Vesicle Fusion with Target Cells

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
We present a novel live‐cell imaging assay for detection of extracellular vesicle (EV)‐binding, ‐uptake, and ‐fusion in time and space. Using EVs carrying the fusogen VSV‐G, we demonstrate real‐time imaging of EV‐fusion, quantification of fusion kinetics and efficiency, and subcellular localization of fusion events.
Jasper van den Ende, Kyra A. Y. Defourny, Huib H. Rabouw, Marvin E. Tanenbaum, Richard W. Wubbolts, Esther N. M. Nolte‐‘t Hoen   +5 more
wiley   +1 more source

RUNX2 Represses the EWS-FLI1-mediated Transcription in Ewing's Sarcoma Cells. [PDF]

Cancer Genomics Proteomics
Kitagawa T, Baron B, Okita H, Hamada J, Nakagawa K, Kobayashi M, Ohta T, Kuramitsu Y.   +7 more
europepmc   +1 more source