Results 121 to 130 of about 319,296 (404)
In highly trained female athletes, haematological and inflammatory biomarkers were found to be independent of menstrual cycle phase, but oral contraceptive use increased transferrin, reticulocyte count and triglycerides and decreased interleukin‐6.
Katia Collomp+12 more
wiley +1 more source
LEPTIN RESISTANCE AND TYPE 2 DIABETES
Leptin is one of adipocyte-secreted hormones. It signals to the brain and other tissues about the status of body energy reserves. Circulating leptin levels are directly proportional to the amount of the body fat.
O. M. Oleshchuk, H. Ya. Loi
doaj +1 more source
Regulatory T cell proliferative potential as novel marker to investigate immune tolerance and clinical progression in Multiple Sclerosis [PDF]
In autoimmune disorders such as Multiple Sclerosis (MS) one of the determining alteration is the breakdown of self-antigen immune-tolerance. Peripheral immune tolerance is maintained, at least in part, by Regulatory T cells (Treg).
Carbone, Fortunata
core +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang+7 more
wiley +1 more source
The role of leptin in selected skin diseases
Leptin is an adipokine, adipocyte-derived compound, which acts both as a hormone and cytokine. It is mainly synthesized by adipocytes of white adipose tissue. Leptin possesses pleiotropic functions including, among others, stimulation of angiogenesis and
Klaudia Dopytalska+4 more
doaj +1 more source
Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation. [PDF]
Genome wide association studies (GWAS) in obesity have identified a large number of noncoding loci located near genes expressed in the central nervous system.
Ahituv, Nadav+6 more
core +1 more source
Obesity Induces Hypothalamic Endoplasmic Reticulum Stress and Impairs Proopiomelanocortin (POMC) Post-translational Processing [PDF]
It was shown previously that abnormal prohormone processing or inactive proconverting enzymes that are responsible for this processing cause profound obesity.
Cakir, Isin+6 more
core +1 more source
Leptin resensitisation: a reversion of leptin-resistant states [PDF]
Leptin resistance refers to states in which leptin fails to promote its anticipated effects, frequently coexisting with hyperleptinaemia. Leptin resistance is closely associated with obesity and also observed in physiological situations such as pregnancy and in seasonal animals.
Maria Florencia Andreoli+5 more
openaire +5 more sources
The study of translational tiling with Fourier Analysis [PDF]
This is a survey on the subject of the title corresponding to three lectures I gave in June 2001 at the Workshop on Fourier Analysis and Convexity, at the Universita di Milano-Biccoca.
arxiv
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia+2 more
wiley +1 more source