Results 141 to 150 of about 151,999 (312)
Pediatric Investigation, EarlyView.Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil +2 more
wiley +1 more source
Embracing new ideas: an interview with Maria Leptin. Interview by Kristin H. Kain.
, 2010 Maria Leptin works simultaneously in the independent fields of immunology and development. She is the new director of the European Molecular Biology Organization (EMBO) and runs a laboratory in Heidelberg, as well as one in Cologne.
Leptin, Maria, Kain, K. H.
core +1 more source
Pediatric Investigation, EarlyView.This evidence map of 63 studies (n = 6158) showed growth hormone therapy in children with growth hormone deficiency has neutral glucose effects, mixed lipid outcomes, potential benefits for bone mineral density, bone mineral content, and parathyroid hormone, but generally no impact on thyroid function, body composition, or body mass index.
Wei Wu +6 more
wiley +1 more source
PROTEOMICS, EarlyView.ABSTRACT The advent of proteomics assays that provide accurate levels of thousands of proteins from relatively small sample volumes opens possibilities for biomarker research in biobanks with valuable samples. In this study, we leverage the applicability of the Olink proximity extension assay to profile serum samples of the Janus Serum Bank, which have
Steffan Daniel Bos +4 more
wiley +1 more source
Leptin and hypertension in obesity
, 2006 Paco E Bravo1, Stephen Morse1, David M Borne2, Erwin A Aguilar1, Efrain Reisin11Sections of Nephrology and 2Comprehensive Medicine, Department of Internal Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, USAAbstract: Leptin ...
Efrain Reisin +4 more
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When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble
Portal Hypertension &Cirrhosis, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen +5 more
wiley +1 more source
, 2013 Cleto Alvarez-Aguilar,1–3 Alfonso Rafael Alvarez-Paredes,2 Bengt Lindholm,4 Peter Stenvinkel,4 Elvia García-López,4 Oliva Mejía-Rodríguez,5 Joel Edmundo López-Meza,6 Dante Amato,7 Ramon Paniagua8 1Hospital General
Alvarez-Aguilar C +8 more
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Leptin In Malign Pleural Efusions: May Be A New Marker?
, 2011 Objective: The pleural effusions may be caused by malignant or benign diseases. In this study, it was aimed to determine the serum and pleural leptin levels in non-malignant and malignant pleural effusions.Methods: Patients with non-malignant (n=20) and ...
Serap Duru +6 more
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Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review
Phytotherapy Research, EarlyView.ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley +1 more source
, 2011 In autoimmune disorders such as Multiple Sclerosis (MS) one of the determining alteration is the breakdown of self-antigen immune-tolerance. Peripheral immune tolerance is maintained, at least in part, by Regulatory T cells (Treg).
Carbone, Fortunata
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