Results 121 to 130 of about 151,999 (312)

Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice

Reproductive Biology and Endocrinology, 2018
Background Serum leptin levels are augmented in obese infertile men and in men with azoospermia. They also correlate inversely with sperm concentration, motility and normal forms.
Xiaotong Wang, Xiaoke Zhang, Lian Hu, Honggang Li   +3 more
doaj   +1 more source

Patient and public involvement in randomized trials of lifestyle intervention among pregnant women with obesity: An umbrella review

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Obesity increases the risk of obstetric and neonatal complications, and adherence to lifestyle interventions during pregnancy presents a challenge. Patient and public involvement (PPI) in trials may foster a more patient‐centered approach, potentially improving compliance with intervention and follow up.
Elisabeth Garcia Vilaplana, Andrea Vigaray Galera, Carmen Amezcua‐Prieto, Khalid Saeed Khan, Aurora Bueno‐Cavanillas, Begoña Martínez de Tejada, Naomi Cano‐Ibáñez   +6 more
wiley   +1 more source

Sleep deprivation aggravates hepatocytes steatosis and insulin resistance by regulating exosomal microRNAs

Interdisciplinary Medicine, EarlyView.
Sleep deprivation accelerates the progression of MASLD and IR by up‐regulating the expression of miR‐3572‐5p and down‐regulating the expression of miR‐183‐5p in circulating exosomes, thereby inhibiting fatty acid β‐oxidation and disrupting insulin signaling pathways. Abstract Sleep deprivation (SD) threatens human health and increases the prevalence of 
Xinxin Xu, Lulu Li, Ying Cao, Ying Wang, Chao Yang, Alexander Nikolaevich Orekhov, Yuanfeng Lu, Houbin Chu, Chuanrong Zhao, Guixue Wang, Guohua Song   +10 more
wiley   +1 more source

Elevated cord leptin from low B12 mothers predicts birth weight

, 2014
Vitamin B12 (B12) insufficiency is common in pregnancy and independently predicts insulin resistance (IR) in the offspring. B12 is an important key nutrient for epigenetic programming through regulating DNA methylation.
Wood, C, Saravanan, P, Sivakumar, K, Tripathi, G, Vatish, M, Webster, C, Anderson, N, Lawson, A, Antonysunil, A, McTernan, P   +9 more
core   +1 more source

Effect of periodontal treatment on adipokines in patients with type 2 diabetes mellitus: A systematic review

Journal of Periodontology, EarlyView.
Abstract Background Periodontal disease (PD) is associated with type 2 diabetes mellitus (T2DM), while periodontal treatment (PT) improves glycemic control in T2DM patients. Leptin and adiponectin belong to the adipokines family and have almost antagonistic functions in inflammatory processes and insulin sensitivity modulation.
Natalia Christaki, Dimitra Baladina, Panagiotis A. Koromantzos, Yiorgos A. Bobetsis   +3 more
wiley   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen, Didem Şöhretoğlu, Ayşe Kuruüzüm‐Uz   +2 more
wiley   +1 more source

Cutaneous Pigmentary Changes During Setmelanotide Therapy: Dermoscopic and Confocal Findings in Two Patients

JEADV Clinical Practice, EarlyView.
ABSTRACT Setmelanotide is a melanocortin‐4 receptor agonist approved for the treatment of rare forms of genetic obesity. Through off‐target activation of the melanocortin‐1 receptor, it may induce cutaneous pigmentation changes; however, data regarding its effects on melanocytic nevi remain limited.
Martina Cavicchi, Claudia Lasagni, Silvana Ciardo, Francesca Giusti, Albino Eccher, Caterina Longo   +5 more
wiley   +1 more source

Adaptive Evolution of Leptin in Heterothermic Bats

, 2011
PMCID: PMC3217946This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Stephen J Rossiter, Shuyi Zhang, Yuan Lihong, Zuo, X, Zuo Xueguo, Gareth Jones, He, Guimei, Lin Benfu, Rossiter Stephen J., Rossiter, SJ, Zhang, Shuyi, Lin, B, Zhao, X, Zhao Xudong, Geiser Fritz, Geiser, F, Lihong Yuan, Yuan, Lihong, Fritz Geiser, He Guimei, He Lingjiang, Rossiter, Stephen J, Geiser, Fritz, He, Lingjiang, Zhang, S, Lingjiang He, Zuo, Xueguo, Lin, Benfu, Stephen J. Rossiter, Xudong Zhao, He, G, Zhao, Xudong, Yuan, L, Guimei He, Zhang Shuyi, Benfu Lin, Xueguo Zuo, He, L, Jones Gareth, Jones, Gareth, Jones, G   +40 more
core   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Mechanisms underlying leptininduced cardioprotection

, 2010
BACKGROUND: The tissue damage resulting from myocardial ischaemia/reperfusion (I/R) leads to a large proportion of the deaths in the developed world.
Dixon, R.A.
core