Selective PPARα Modulator Pemafibrate Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease Through Regulation of Leptin Signaling and Remodeling of Gut Microbiota. [PDF]
Yamamoto K +12 more
europepmc +1 more source
Summary Management of type 2 diabetes includes medications that can unintentionally increase obesity and insulin resistance. This unblinded, single‐centre, randomised controlled trial focused on rural Australian adults with type 2 diabetes (aged 18–75 and body mass index [BMI] >30 kg/m2), measuring the effectiveness of a tailored interdisciplinary ...
Giuliana O. Murfet +3 more
wiley +1 more source
Leptin, adiponectin levels and their ratios in women with polyendocrine metabolic ovarian syndrome: a systematic review and meta-analysis. [PDF]
Shi X, Zhang W.
europepmc +1 more source
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton +4 more
wiley +1 more source
Obesity-driven adipokine signaling in breast cancer: mechanistic insights, therapeutic challenges, and opportunities for precision oncology. [PDF]
Soonu VK +4 more
europepmc +1 more source
Abstract Children with neurological impairment (CNI) are at increased risk of malnutrition because of functional, medical, and socioeconomic challenges. However, difficulties in obtaining reliable anthropometric measurements and differences in body composition limit the usefulness of conventional nutritional indicators.
Sarah Vermilyea +19 more
wiley +1 more source
Serum insulin and leptin levels and their association with taste perception and eating behavior following bariatric surgery: A prospective study. [PDF]
Asadi AH +7 more
europepmc +1 more source
ABSTRACT Aim Lipodystrophy syndromes are rare diseases with metabolic and cardiovascular consequences. This study explores the metabolic and renal effects of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in patients with genetic lipodystrophy. Patients and Methods Patients with familial partial lipodystrophy (n = 57) or congenital generalised ...
Léna Robert +12 more
wiley +1 more source
Alterations in Human Milk Adiponectin, Leptin, Resistin, and microRNAs in Mothers With Gestational Diabetes Mellitus Compared With Healthy Controls: A Systematic Review and Network-Based Analysis. [PDF]
Zhang Z +8 more
europepmc +1 more source
Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley +1 more source

