Results 171 to 180 of about 165,445 (252)

Leptin and autoimmunity: role of leptin in the modulation of immune response during Experimental Autoimmune Encephalomyelitis [PDF]

, 2008
Procaccini, Claudio
core   +1 more source

Serum Lipidomics Profiling Identify Novel Biomarkers of Distal Symmetrical Polyneuropathy in Type 1 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Distal symmetrical polyneuropathy (DSPN) is a common complication of type 1 diabetes (T1D), yet validated biomarkers for early detection or prognosis are lacking. Metabolic disturbances driven by chronic hyperglycemia and dyslipidemia contribute to DSPN development and progression.
Tik Muk, Tina Okdahl, Marietta Kokla, Tommi Suvitaival, Gurjeet Kaur, Ismo M. Mattila, Simon M. Kienle, Christian Buhl, Knud Yderstræde, Troels S. Jensen, Peter Rossing, Flemming Pociot, Birgitte Brock, Cristina Legido‐Quigley, Páll Karlsson, Christian S. Hansen, Christina Brock, Joachim Størling, Karolina Sulek   +18 more
wiley   +1 more source

Effect of weight loss intervention on fat metabolism including adipocytokines and enzymes in children with simple obesity. [PDF]

PLoS One
He PL, Wang YY, Li SH, Wang SQ, Sun LL, Chang XN, Gu HL, Ma XY, Cai SS, Li RZ.   +9 more
europepmc   +1 more source

Evaluating Whole Fruit Feijoa Powder for Type 2 Diabetes Risk Prevention: A Randomised Controlled Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Low energy diets (LEDs) are effective for body weight (BW) loss and improvement of type 2 diabetes (T2D) risk biomarkers. Emerging evidence suggests that whole fruit feijoa powder, rich in polyphenols and abscisic acid, may further support T2D prevention.
I. A. Mohamed, I. R. Sequeira‐Bisson, J. J. Lim, L. D. Plank, R. Murphy, S. D. Poppitt, J. L. Miles‐Chan   +6 more
wiley   +1 more source

Improvements in sleep, weight, and eating-disorder symptoms following off-label leptin treatment in an adolescent with chronic anorexia nervosa and insomnia: a case report. [PDF]

J Eat Disord
Dück A, Zhu H, Melinat J, Kruzer M, Berger C, Kölch M, Reinhardt M, Brehme H, Zimmermann A, Frintrop L, Reis O.   +10 more
europepmc   +1 more source

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding, Qing Liu, Qiong Luo, Xiaojun Yao, Xingxing Fan   +4 more
wiley   +1 more source

Food additives with aldehyde skeleton exhibited leptin resistance in cells. [PDF]

Front Nutr
Shibuya Y, Yoshida H, Tsuge K, Hamasaki Y, Kuriya K, Nakagawa T, Sugiyama A, Miyamoto K, Shimamoto A, Jockers R, Dam J, Hosoi T.   +11 more
europepmc   +1 more source

Non‐Invasive Fibrosis Testing in Adults With Obesity and MASLD: A Systematic Review and Meta‐Analysis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Adults with obesity are at increased risk of metabolic dysfunction‐associated steatotic liver disease (MASLD)‐related fibrosis, but the diagnostic performance of non‐invasive tests (NITs) in this population remains uncertain. This meta‐analysis evaluated NITs for detecting significant (≥F2) and advanced (≥F3) fibrosis in adults with ...
Patricia M. Ortega, Lucas Sabatella, Pinelopi Manousou, Adriana Arregui, Ahmed R. Ahmed, Chioma Izzi‐Engbeaya   +5 more
wiley   +1 more source

Association Between Relative Cord Hyperleptinemia and Offspring Outcomes in Pregnant Women With Overweight or Obesity. [PDF]

Pediatr Obes
Immanuel J, Chirayath S, Harreiter J, Desoye G, Corcoy R, Adelantado JM, Devlieger R, Lapolla A, Dalfra MG, Bertolotto A, Wender-Ozegowska E, Zawiejska A, Dunne FP, Damm P, Mathiesen ER, Jensen DM, Andersen LLT, Tanvig MH, Hill DJ, Jelsma JGM, Kautzky-Willer A, Galjaard S, Snoek FJ, van Poppel MNM, Simmons D.   +24 more
europepmc   +1 more source

Obesity Modifies Sphingolipid Signatures in Childhood Asthma

Clinical &Experimental Allergy, EarlyView.
Harshita Shailesh, Alaa Abdelhamid, Ahmed Arabi, Yaman Al‐Haneedi, Shana Jacob, Giridhara Rathnaiah Babu, Stefan Worgall, Ibrahim Janahi   +7 more
wiley   +1 more source