Results 171 to 180 of about 239,997 (210)

Leptin, leptin soluble receptor and coronary atherosclerosis

Experimental and Clinical Endocrinology & Diabetes, 2007
AbstractBackground  The adipose tissue‐related hormone leptin plays an important role in the regulation of body weight. The associations of leptin and leptin soluble receptor (sOb‐R) with coronary artery disease (CAD) are not clear.Design  We measured leptin and sOb‐R in 543 consecutive patients (379 men, 164 women) referred for coronary angiography ...
G, Hoefle, C H, Saely, L, Risch, P, Rein, L, Koch, F, Schmid, S, Aczél, T, Marte, P, Langer, H, Drexel   +9 more
openaire   +2 more sources

Leptin, Obesity, and Leptin Resistance

2014
The cloning of leptin in 1994 was an important milestone in obesity research. In those days obesity was rather stigmatized as a condition caused by lack of character and self-control. With leptin and its receptor being the first single genes that could cause morbid obesity in man and mice, it is now appreciated that obesity is caused by a dysregulation
Heike Münzberg, Steven B. Heymsfield
openaire   +1 more source

Leptin-Signaling Pathways and Leptin Resistance

2009
Leptin acts as an anorexigenic hormone in the brain, where the long form of the leptin receptor (LRb) is widely expressed in hypothalamic and extra-hypothalamic sites that are known to participate in diverse feeding circuits. The important role of leptin in energy homeostasis is demonstrated by the profound hyperphagia and morbid obesity in humans and ...
openaire   +2 more sources

[Leptin: adipocyte hormone].

Recenti progressi in medicina, 1998
The authors reviewed the most recent literature on leptin, a protein produced by adipocytes which exerts its action on hypothalamus, modifying eating behavior and inhibiting the lust for food consumption. This one appeared to be the main, if not the only, physiologic action of leptin.
CASTAGNA L, DE GREGORIO T, ALLEGRA, Alessandro, BUEMI, Michele, CORSONELLO A, BONANZINGA S, CATANOSO M, CERUSO D, CORICA, Francesco   +8 more
openaire   +3 more sources

[Leptin Signalings and Leptin Resistance].

Sheng li ke xue jin zhan [Progress in physiology], 2016
Leptin plays a critical role in the regulation of energy balance and metabolic homeostasis. Impairment of leptin function is closely involved in the pathogenesis of obesity, diabetes mellitus and some other metabolic diseases. Leptin initiates intracellular signal transductions in the leptin-receptor-expressing neurons in the central nervous system to ...
Xiao-Ning, Yang, Chen-Yu, Zhang, , Wang Bing-Wei, Shi-Gong, Zhu, Rui-Mao, Zheng   +4 more
openaire   +1 more source

Leptin

Medicinal Research Reviews, 1997
X, Remesar, I, Rafecas, J A, Fernández-López, M, Alemany   +3 more
openaire   +2 more sources

Chicken leptin

General and Comparative Endocrinology, 2008
P J, Sharp, I C, Dunn, D, Waddington, T, Boswell   +3 more
openaire   +2 more sources

Leptin ve Leptin Direnci

2023
openaire   +1 more source

Leptin receptor-expressing pericytes mediate access of hypothalamic feeding centers to circulating leptin

Cell Metabolism, 2021
Clément Bourguignon
exaly  

Leptin revisited: its mechanism of action and potential for treating diabetes

Nature Reviews Drug Discovery, 2012
Roberto Coppari
exaly