Results 141 to 150 of about 76,631 (314)

Prenatal Environmental Hypoxia Enhances Adult Hypoxia Tolerance in Brandt's Voles (Lasiopodomys brandtii): Behavioral and Transcriptomic Insights

Integrative Zoology, EarlyView.
Prenatal hypoxia enhances adult hypoxia tolerance in Brandt's voles, preserving cognitive and memory functions. Transcriptomic analysis reveals adaptive changes in energy metabolism, oxygen transport, and neuroprotective mechanisms, highlighting developmental plasticity.
Mengyang Li, Congcong Qiao, Xiujuan Li, Maolin Huang, Zhenlong Wang, Luye Shi   +5 more
wiley   +1 more source

Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice

Allergy, EarlyView.
Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek, Andrea Deinzer, Roman G. Gerlach, Jana Petzold, Lea Semmler, Christof Vorsatz, Padraic G. Fallon, Christian Schwartz   +7 more
wiley   +1 more source

Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders

Andrology, EarlyView.
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret, Aaran H. Patel, Elisabeth Daniels, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

Andrology, EarlyView.
Abstract Background The constitutive Leydig cell hormone insulin‐like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declining into old age.
Richard Ivell, Bilal Tulumcu, Waleed Alhujaili, Ravinder Anand‐Ivell   +3 more
wiley   +1 more source

Leptin receptor gene deficiency minimally affects osseointegration in rats. [PDF]

Sci Rep, 2023
Jolic M, Ruscsák K, Emanuelsson L, Norlindh B, Thomsen P, Shah FA, Palmquist A.   +6 more
europepmc   +1 more source

Clinical Impact of the Leptin to Soluble Leptin Receptor Ratio on Subclinical Carotid Atherosclerosis in Patients with Type 2 Diabetes

, 2012
Yuko Yamazaki, Masanori Emoto, Tomoaki Morioka, Naoya Kawano, Eiko Lee, Hiromi Urata, Shoko Tsuchikura, Koka Motoyama, Katsuhito Mori, Shinya Fukumoto, Tetsuo Shoji, Yoshiki Nishizawà, Masaaki Inaba   +12 more
openalex   +2 more sources

Bidirectional Crosstalk between Leptin and Insulin-like Growth Factor-I Signaling Promotes Invasion and Migration of Breast Cancer Cells via Transactivation of Epidermal Growth Factor Receptor [PDF]

, 2008
Neeraj K. Saxena, Meena M. Balgopal, Brandi B. Knight, Didier Merlin, Frank A. Anania, Ruth O’Regan, Dipali Sharma   +6 more
openalex   +1 more source

Age‐ and Sex‐Adjusted Body Mass Index Increases in Childhood Acute Lymphoblastic Leukaemia Patients From Diagnosis to Five‐Year Follow‐Up

Acta Paediatrica, EarlyView.
ABSTRACT Aim Children with acute lymphoblastic leukaemia (ALL) are at risk of metabolic and cardiovascular complications. We evaluated the development of overweight and obesity for 5 years after diagnosis in children and adolescents treated for ALL. Methods The medical records of children diagnosed with ALL at one centre during 2000–2018 were assessed.
Aino Kytömäki, Anu Huurre, Päivi M. Lähteenmäki, Tero Vahlberg, Liisa S. Järvelä   +4 more
wiley   +1 more source

Serum Leptin Receptor and the rs1137101 Variant of the LEPR Gene Are Associated with Bladder Cancer. [PDF]

Biomolecules, 2023
Alfaqih MA, Elsalem L, Nusier M, Mhedat K, Khader Y, Ababneh E.   +5 more
europepmc   +1 more source

Characterization and functional studies of adiponectin and leptin receptor in grass carp

, 2015
Shuang Chen
openalex   +1 more source