Results 21 to 30 of about 2,380,940 (353)

Role of leptin and leptin receptor in inflammation

open access: yesAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2003
on october 30th, 2002, the World Health Report by the World Health Organization was launched subtitled Reducing risks, promoting healthy life . Many of the health risks discussed in this report concern food consumption—either too little, in the case of the poor, or too much, in the case of ...
Halle, Martin, Persson, P. B.
openaire   +4 more sources

Leptin and leptin receptor expression in breast carcinomas and their relationship with clinicopathological features

open access: yesHuman Pathology Reports, 2022
Context: Breast cancer is the most common cancer and the most common cause of death from cancer among women. Leptin is thought to play role in cell proliferation.
Irem Atalay Karacay   +5 more
doaj  

Cleavage of the leptin receptor by matrix metalloproteinase–2 promotes leptin resistance and obesity in mice

open access: yesScience Translational Medicine, 2018
Matrix metalloproteinase–2 inhibition rescued leptin receptor expression in the hypothalamus and reduced fat accumulation in rodent models of obesity.
R. Mazor   +9 more
semanticscholar   +1 more source

Leptin and Obesity: Role and Clinical Implication

open access: yesFrontiers in Endocrinology, 2021
The peptide hormone leptin regulates food intake, body mass, and reproductive function and plays a role in fetal growth, proinflammatory immune responses, angiogenesis and lipolysis. Leptin is a product of the obese (ob) gene and, following synthesis and
M. Obradović   +7 more
semanticscholar   +1 more source

Monitoring the Expression of Leptin Receptor in Avian Model

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
In this study we carried the expression of leptin receptor in organs and abdominal fat of broiler chickens. The leptin receptor is a member of the class I cytokine receptor family, also known as the gpl30 receptor family, although unlike many other ...
Ľubica Mrázová   +2 more
doaj  

The Effects of Laparoscopic Sleeve Gastrectomy on the Parameters of Leptin Resistance in Obesity

open access: yesBiomolecules, 2019
Obesity is a growing public health problem worldwide. Bariatric surgical procedures achieve the most sustainable and efficacious outcomes in the treatment of morbid obesity.
Tagleb S. Mazahreh   +7 more
doaj   +1 more source

Leptin Receptor Blockade Attenuates Hypertension, but Does Not Affect Ventilatory Response to Hypoxia in a Model of Polygenic Obesity

open access: yesFrontiers in Physiology, 2021
BackgroundObesity can cause hypertension and exacerbates sleep-disordered breathing (SDB). Leptin is an adipocyte-produced hormone, which increases metabolic rate, suppresses appetite, modulates control of breathing, and increases blood pressure.
Lenise J. Kim   +9 more
doaj   +1 more source

Obesity as a Risk Factor for Dementia and Alzheimer’s Disease: The Role of Leptin

open access: yesInternational Journal of Molecular Sciences, 2022
Obesity is a growing worldwide health problem, affecting many people due to excessive saturated fat consumption, lack of exercise, or a sedentary lifestyle.
J. A. Flores-Cordero   +5 more
semanticscholar   +1 more source

Leptin receptor-expressing bone marrow stromal cells are myofibroblasts in primary myelofibrosis

open access: yesNature Cell Biology, 2017
Bone marrow fibrosis is a critical component of primary myelofibrosis (PMF). However, the origin of the myofibroblasts that drive fibrosis is unknown.
M. Decker   +6 more
semanticscholar   +1 more source

Leptin secretion and leptin receptor in the human stomach [PDF]

open access: yesGut, 2000
The circulating peptide leptin produced by fat cells acts on central receptors to control food intake and body weight homeostasis. Contrary to initial reports, leptin expression has also been detected in the human placenta, muscles, and recently, in rat gastric chief cells.
Thérèse Lehy   +10 more
openaire   +3 more sources

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