Results 21 to 30 of about 76,631 (314)

Leptin Receptor Blockade Attenuates Hypertension, but Does Not Affect Ventilatory Response to Hypoxia in a Model of Polygenic Obesity

open access: yesFrontiers in Physiology, 2021
BackgroundObesity can cause hypertension and exacerbates sleep-disordered breathing (SDB). Leptin is an adipocyte-produced hormone, which increases metabolic rate, suppresses appetite, modulates control of breathing, and increases blood pressure.
Lenise J. Kim   +9 more
doaj   +1 more source

Anti-leptin receptor antibody mimics the stimulation of lipolysis induced by leptin in isolated mouse fat pads

open access: yesJournal of Lipid Research, 2001
An anti-leptin receptor polyclonal antibody (receptor antibody), as well as leptin, stimulated the release of free fatty acids from isolated mouse fat pads in a time-dependent manner.
Natsuyo Kawaji   +4 more
doaj   +1 more source

Leptin receptor signaling: pathways to leptin resistance

open access: yesFrontiers in Bioscience, 2011
The identification of spontaneous mutations in the leptin- and leptin receptor (ObR)-encoding ob and db gene, respectively, opened up a new field in obesity research. Leptin, an adipocyte-derived hormone, mirrors the body's fat stores and thereby informs the brain about the body's energy status.
Joris, Wauman, Jan, Tavernier
openaire   +2 more sources

Evaluation of the leptin receptor in human spermatozoa

open access: yesReproductive Biology and Endocrinology, 2010
Background Leptin, a 167 amino acid peptide hormone, profoundly effects reproduction exerting its biological effects via interaction with the leptin receptor (ObR) which is widely expressed on peripheral tissues.
Ghaedi Kamran   +8 more
doaj   +1 more source

Estimation of Leptin and Leptin Receptor Concentrations in Seminal Plasma of Primary Infertile Men

open access: yesمجلة كلية الطب, 2017
Background: There are many sources for Leptin secretion, and it is activated by binding with its receptor known as leptin receptor, that play a role in male infertility.
Ruqaya M. AL-Barzinji   +1 more
doaj   +1 more source

Leptin and Soluble Leptin Receptor in Follicular Fluid [PDF]

open access: yesJournal of Assisted Reproduction and Genetics, 2003
Previous studies suggest that follicular fluid leptin levels predict successful assisted reproduction. The relationship between intrafollicular leptin and the soluble leptin receptor, ovarian hormones, and oocyte quality was examined to determine potential factors contributing to this finding.Follicular fluid leptin, soluble leptin receptor, hormones ...
Corrine K, Welt   +3 more
openaire   +2 more sources

Associations between serum leptin levels, hyperlipidemia, and cholelithiasis in dogs. [PDF]

open access: yesPLoS ONE, 2017
Leptin and its receptor play several physiological roles in the canine gallbladder, and the dysregulation of leptin might play a role in the pathogenesis of gallbladder diseases such as gallbladder mucocele.
Sungin Lee, Oh-Kyeong Kweon, Wan Hee Kim
doaj   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode   +16 more
wiley   +1 more source

C-Reactive Protein (CRP) and Leptin Receptor in Obesity: Binding of Monomeric CRP to Leptin Receptor

open access: yesFrontiers in Immunology, 2018
While leptin deficiency or dysfunction leads to morbid obesity, obese subjects are characterized paradoxically by hyperleptinemia indicating lack of response to leptin.
Manu Sudhakar   +4 more
doaj   +1 more source

Expression of leptin and leptin receptor transcript in ovine corpus luteum [PDF]

open access: yesIranian Journal of Veterinary Medicine, 2018
Background: Leptin, the product of the obesity (ob) gene, acts as a signaling adipokine for modulating food intake, energy metabolism and reproductive functions in mammals. Leptin’s effects on the reproductive system at various levels of the hypothalamic-
Mozaffar Karimzadeh Koshkghazi   +1 more
doaj   +1 more source

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