Results 41 to 50 of about 1,272,125 (151)

Associations between serum leptin levels, hyperlipidemia, and cholelithiasis in dogs. [PDF]

open access: yesPLoS ONE, 2017
Leptin and its receptor play several physiological roles in the canine gallbladder, and the dysregulation of leptin might play a role in the pathogenesis of gallbladder diseases such as gallbladder mucocele.
Sungin Lee, Oh-Kyeong Kweon, Wan Hee Kim
doaj   +1 more source

Role of Leptin and metabolism in survival of autoreactive CD4+ T cells [PDF]

open access: yes, 2009
Recent evidence has shown that leptin, the adipose-tissue derived hormone, can influence T cell homeostasis and survival through the control of genes involved in these processes. Leptin deficient ob/ob mice and humans show reduced circulating number of T
Galgani, Mario
core   +1 more source

Leptin receptor in the chicken ovary: potential involvement in ovarian dysfunction of ad libitum-fed broiler breeder hens

open access: yesReproductive Biology and Endocrinology, 2004
In hens, the ovarian follicles committed to ovulation are arranged in an ordered follicular hierarchy. In standard broiler breeders hens genetically selected for high growth rate the reproductive function is clearly dysfunctional.
Collin Anne   +5 more
doaj   +1 more source

Leptin receptor in boar spermatozoa [PDF]

open access: yesInternational Journal of Andrology, 2007
SummaryLeptin is active in both metabolism and reproduction. In fact, it seems to exert an inhibitory action on gonadal functions by reducing testosterone production. The presence of leptin in human and boar seminal plasma and in human spermatozoa has been demonstrated; recently, leptin receptors (Ob‐R) have been localized in human spermatozoa, thus ...
DE AMBROGI, MARCO   +3 more
openaire   +2 more sources

C-Reactive Protein (CRP) and Leptin Receptor in Obesity: Binding of Monomeric CRP to Leptin Receptor

open access: yesFrontiers in Immunology, 2018
While leptin deficiency or dysfunction leads to morbid obesity, obese subjects are characterized paradoxically by hyperleptinemia indicating lack of response to leptin.
Manu Sudhakar   +4 more
doaj   +1 more source

Expression of leptin and leptin receptor transcript in ovine corpus luteum [PDF]

open access: yesIranian Journal of Veterinary Medicine, 2018
Background: Leptin, the product of the obesity (ob) gene, acts as a signaling adipokine for modulating food intake, energy metabolism and reproductive functions in mammals. Leptin’s effects on the reproductive system at various levels of the hypothalamic-
Mozaffar Karimzadeh Koshkghazi   +1 more
doaj   +1 more source

Polymorphisms of Leptin (-2548 G/A) and Leptin Receptor (Q223R) Genes in Iranian Women with Breast Cancer

open access: yesInternational Journal of Genomics, 2015
Recent studies have shown that polymorphisms in leptin and leptin receptor genes are associated with increased risk for breast cancer. This study aimed at investigating -2548 G/A polymorphism in leptin gene and Q223R polymorphism in leptin receptor gene ...
Reza Mahmoudi   +4 more
doaj   +1 more source

Leptin and Leptin Receptor Expression in Breast Cancer [PDF]

open access: yesCancer Research and Treatment, 2009
Leptin is a multifunctional hormone that's produced by adipose tissue and leptin is involved in the regulation of food intake and energy balance. The aims of this study were to determine the leptin and leptin receptor (Ob-R) expressions in human breast cancer and their corresponding influence on the prognosis of patients with breast cancer.We examined ...
openaire   +2 more sources

Leptin interferes with 3',5'-Cyclic Adenosine Monophosphate (cAMP) signaling to inhibit steroidogenesis in human granulosa cells

open access: yesReproductive Biology and Endocrinology, 2009
Background Obesity has been linked to an increased risk of female infertility. Leptin, an adipocytokine which is elevated during obesity, may influence gonadal function through modulating steroidogenesis in granulosa cells.
HoYuen Basil   +5 more
doaj   +1 more source

Leptin and leptin resistance in obesity: current evidence, mechanisms and future directions

open access: yesEndocrine Connections
Leptin, a key adipokine regulating energy homeostasis, has been extensively studied for its potential in the management of obesity. However, its therapeutic efficacy is often limited due to leptin resistance.
Wenjing Hu, Huijuan Zhu, Fengying Gong
doaj   +1 more source

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