Results 41 to 50 of about 1,272,125 (151)
Associations between serum leptin levels, hyperlipidemia, and cholelithiasis in dogs. [PDF]
Leptin and its receptor play several physiological roles in the canine gallbladder, and the dysregulation of leptin might play a role in the pathogenesis of gallbladder diseases such as gallbladder mucocele.
Sungin Lee, Oh-Kyeong Kweon, Wan Hee Kim
doaj +1 more source
Role of Leptin and metabolism in survival of autoreactive CD4+ T cells [PDF]
Recent evidence has shown that leptin, the adipose-tissue derived hormone, can influence T cell homeostasis and survival through the control of genes involved in these processes. Leptin deficient ob/ob mice and humans show reduced circulating number of T
Galgani, Mario
core +1 more source
In hens, the ovarian follicles committed to ovulation are arranged in an ordered follicular hierarchy. In standard broiler breeders hens genetically selected for high growth rate the reproductive function is clearly dysfunctional.
Collin Anne +5 more
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Leptin receptor in boar spermatozoa [PDF]
SummaryLeptin is active in both metabolism and reproduction. In fact, it seems to exert an inhibitory action on gonadal functions by reducing testosterone production. The presence of leptin in human and boar seminal plasma and in human spermatozoa has been demonstrated; recently, leptin receptors (Ob‐R) have been localized in human spermatozoa, thus ...
DE AMBROGI, MARCO +3 more
openaire +2 more sources
C-Reactive Protein (CRP) and Leptin Receptor in Obesity: Binding of Monomeric CRP to Leptin Receptor
While leptin deficiency or dysfunction leads to morbid obesity, obese subjects are characterized paradoxically by hyperleptinemia indicating lack of response to leptin.
Manu Sudhakar +4 more
doaj +1 more source
Expression of leptin and leptin receptor transcript in ovine corpus luteum [PDF]
Background: Leptin, the product of the obesity (ob) gene, acts as a signaling adipokine for modulating food intake, energy metabolism and reproductive functions in mammals. Leptin’s effects on the reproductive system at various levels of the hypothalamic-
Mozaffar Karimzadeh Koshkghazi +1 more
doaj +1 more source
Recent studies have shown that polymorphisms in leptin and leptin receptor genes are associated with increased risk for breast cancer. This study aimed at investigating -2548 G/A polymorphism in leptin gene and Q223R polymorphism in leptin receptor gene ...
Reza Mahmoudi +4 more
doaj +1 more source
Leptin and Leptin Receptor Expression in Breast Cancer [PDF]
Leptin is a multifunctional hormone that's produced by adipose tissue and leptin is involved in the regulation of food intake and energy balance. The aims of this study were to determine the leptin and leptin receptor (Ob-R) expressions in human breast cancer and their corresponding influence on the prognosis of patients with breast cancer.We examined ...
openaire +2 more sources
Background Obesity has been linked to an increased risk of female infertility. Leptin, an adipocytokine which is elevated during obesity, may influence gonadal function through modulating steroidogenesis in granulosa cells.
HoYuen Basil +5 more
doaj +1 more source
Leptin and leptin resistance in obesity: current evidence, mechanisms and future directions
Leptin, a key adipokine regulating energy homeostasis, has been extensively studied for its potential in the management of obesity. However, its therapeutic efficacy is often limited due to leptin resistance.
Wenjing Hu, Huijuan Zhu, Fengying Gong
doaj +1 more source

