Results 21 to 30 of about 138,647 (310)

Monitoring the Expression of Leptin Receptor in Avian Model

Scientific Papers Animal Science and Biotechnologies, 2023
In this study we carried the expression of leptin receptor in organs and abdominal fat of broiler chickens. The leptin receptor is a member of the class I cytokine receptor family, also known as the gpl30 receptor family, although unlike many other ...
Ľubica Mrázová, Mária Angelovičová, Martin Král   +2 more
doaj  

Fluticasone furoate maintains epithelial homeostasis via leptin/leptin receptor pathway in nasal cells [PDF]

, 2014
Leptin is involved in the lung epithelial homeostasis. Its role in the nasal tract is largely unknown. Allergic rhinitis (AR) is induced by the allergen exposure leading to consequential structural abnormalities in the nasal epithelium.
Ballacchino, A, Bonura, A, Bruno, A, Colombo, P, Ferraro, M, GALLINA, Salvatore, Gerbino, S, GIAMMANCO, Marco, Gjomarkaj, M, LA GRUTTA, Stefania, Pace, E., Siena, L   +11 more
core   +1 more source

Discovery of the elusive leptin in birds: identification of several 'missing links' in the evolution of leptin and its receptor. [PDF]

PLoS ONE, 2014
Leptin is a pleiotropic protein best known for regulation of appetite and fat storage in mammals. While many leptin orthologs have been identified among vertebrates, an authentic leptin in birds has remained elusive and controversial.
Jeremy W Prokop, Cameron Schmidt, Donald Gasper, Robert J Duff, Amy Milsted, Takeshi Ohkubo, Hope C Ball, Matthew D Shawkey, Herman L Mays, Larry A Cogburn, Richard L Londraville   +10 more
doaj   +1 more source

Comparison of Leptin, Leptin Receptor, Vitamin D and Brain-Derived Neurotrophic Factor Levels in Major Depressive Disorder and Attention Deficit and Hyperactivity Disorder in Children and Adolescents

Psychiatry and Behavioral Sciences, 2023
Objective: Data on effects of vitamins, hormones and neurotrophic factors on the etiology of attention deficit hyperactivity disorder (ADHD) and major depressive disorder (MDD) in children is limited.
Dilsad Yildiz Miniksar, Ayse Yesim Gocmen   +1 more
doaj   +1 more source

Exenatide Improves Bone Quality in a Murine Model of Genetically Inherited Type 2 Diabetes Mellitus [PDF]

, 2017
Type 2 diabetes mellitus (T2DM) is associated with skeletal complications, including an increased risk of fractures. Reduced blood supply and bone strength may contribute to this skeletal fragility.
Andreozzi, Anetzberger, Anichini, Aoyama, Baggio, Balint, Ban, Beckman, Bouxsein, Brunton, Chen, Coleman, Dempster, Ealey, Eckel, Feng, Flatt, Friedman, Griffith, Griffith, Hamilton, Hu, Karim, Kim, Lee, Lu, Ma, Mabilleau, Mabilleau, Mansur, Marenzana, Mieczkowska, Napoli, Nuche-Berenguer, Nuche-Berenguer, Nuche-Berenguer, Nystrom, Nystrom, Odgaard, Okerson, Orland, Orriss, Paschalis, Pereira, Pereira, Prisby, Richard, Roche, Roszer, Schalkwijk, Scheller, Selley, Shymkiw, Smits, Stabley, Sun, Tartaglia, Upadhyay, van Bloemendaal, Vijan, Williams, Wu, Yamamoto, Yamamoto, Yamamoto   +64 more
core   +6 more sources

Monitoring leptin activity using the chicken leptin receptor [PDF]

Journal of Endocrinology, 2008
We report on the construction of a leptin bioassay based on the activation of chicken leptin receptor in cultured cells. A human embryonic kidney (HEK)-293 cell line, stably transfected with the full-length cDNA of chicken leptin receptor together with a STAT3-responsive reporter gene specifically responded to recombinant human and Xenopus leptins. The
Gideon, Hen, Sera, Yosefi, Ana, Ronin, Paz, Einat, Charles I, Rosenblum, Robert J, Denver, Miriam, Friedman-Einat   +6 more
openaire   +2 more sources

Leptin, soluble leptin receptor, and free leptin index in patients with metabolic syndrome

Ожирение и метаболизм, 2017
Aim. To assess the levels of leptin, its soluble receptor, and index of the formation of free leptin in metabolic syndrome (MS). Materials and methods. The study included 110 individuals with obesity and overweight.
Elena N. Smirnova, Sofia G. Shulkina
doaj   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

Hepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode, Takahiro Kodama, Satoshi Shigeno, Kazuhiro Murai, Satoshi Tanaka, Justin Y. Newberg, Jumpei Kondo, Shogo Kobayashi, Ryoko Yamada, Hayato Hikita, Ryotaro Sakamori, Hiroshi Suemizu, Tomohide Tatsumi, Hidetoshi Eguchi, Nancy A. Jenkins, Neal G. Copeland, Tetsuo Takehara   +16 more
wiley   +1 more source

Leptin induces IL-6 expression through OBRl receptor signaling pathway in human synovial fibroblasts. [PDF]

PLoS ONE, 2013
BACKGROUND: Leptin, an adipocyte-secreted hormone that centrally regulates weight control, may exert proinflammatory effects in the joint, depending on the immune response.
Wei-Hung Yang, Shan-Chi Liu, Chun-Hao Tsai, Yi-Chin Fong, Shoou-Jyi Wang, Yung-Sen Chang, Chih-Hsin Tang   +6 more
doaj   +1 more source

Leptin Receptor Blockade Attenuates Hypertension, but Does Not Affect Ventilatory Response to Hypoxia in a Model of Polygenic Obesity

Frontiers in Physiology, 2021
BackgroundObesity can cause hypertension and exacerbates sleep-disordered breathing (SDB). Leptin is an adipocyte-produced hormone, which increases metabolic rate, suppresses appetite, modulates control of breathing, and increases blood pressure.
Lenise J. Kim, Mi-Kyung Shin, Huy Pho, Laszlo Otvos, Laszlo Otvos, Laszlo Otvos, Sergio Tufik, Monica L. Andersen, Luu V. Pham, Vsevolod Y. Polotsky   +9 more
doaj   +1 more source