Results 11 to 20 of about 5,255,382 (240)
Surgical Treatment for Leptomeningeal Disease [PDF]
Cancer Control, 2017 Background Advancements in cancer treatment have led to more cases of leptomeningeal disease, which requires a multimodal approach. Methods Treatment modalities are reviewed from a neurosurgical standpoint, focusing on intrathecal chemotherapy and ...
Andrey A. Volkov +2 more
core +3 more sources
Cancer Reports, 2022 Background Leptomeningeal carcinomatosis is a relatively uncommon complication of solid tumors that is associated with significant morbidity and mortality.
Daniel Tesolin +2 more
doaj +2 more sources
Leptomeningeal Disease as a Rare Complication of Primary Penile Urethral Cancer
Case Reports in Oncological Medicine, 2020 Primary penile urethral cancer is a rare genitourinary malignancy arising from the epithelial lining of the urethra. Our patient is a 63-year-old male with newly diagnosed penile urethral carcinoma who presented with headache and was found to have ...
Nan Chen +3 more
doaj +2 more sources
Primary diffuse leptomeningeal oligodendrogliomatosis: A case report and literature review
Indian Journal of Radiology and Imaging, 2016 Primary leptomeningeal oligodendrogliomatosis (PLO) is a rare low-grade intracranial and spinal canal subarachnoid neoplasm without an obvious primary neoplasm in the brain or spinal cord parenchyma. We present here the serial progression of radiological
Amarnath Chellathurai +3 more
doaj +2 more sources
Inflammatory demyelinating polyneuropathy versus leptomeningeal disease following Ipilimumab
Journal for ImmunoTherapy of Cancer, 2018 Background Ipilimumab is an FDA-approved anti-CTLA-4 monoclonal antibody used in treatment of metastatic melanoma. We present an unusual neurological complication of Ipilimumab therapy and the diagnostic dilemma it caused. Case presentation A 42 year old
Lorraine Cafuir +4 more
doaj +2 more sources
Glioblastoma with brainstem leptomeningeal pseudoprogression following radiation therapy
Radiology Case Reports, 2019 In brain tumor patients, worsening of imaging findings in the first 6 months after surgical debulking and chemoradiation can occur in the absence of tumor growth, a phenomenon known as pseudoprogression.
Nikhar Kinger, MD +3 more
doaj +2 more sources
Radiotherapy and Systemic Treatment for Leptomeningeal Disease
BiomedicinesLeptomeningeal disease (LMD) is a devastating sequelae of metastatic spread that affects approximately 5% of cancer patients. The incidence of LMD is increasing due to advancements in systemic therapy and enhanced detection methods.
Kelsey M. Frechette +8 more
doaj +3 more sources
Follicular Lymphoma Presenting with Leptomeningeal Disease [PDF]
Case Reports in Hematology, 2014 Follicular lymphoma is generally an indolent B cell lymphoproliferative disorder of transformed follicular center B cells. Central nervous system metastasis is a very rare complication portending a very poor prognosis. We report a rare case of follicular
Rubens Costa +2 more
doaj +3 more sources
An overview of leptomeningeal disease [PDF]
Annals of Palliative Medicine, 2021 Leptomeningeal disease (LMD) is a poor prognosis pattern of disease progression in patients with metastatic malignancy with limited treatment options. Patients may be asymptomatic or present with non-specific neurologic deficits, therefore gadolinium-enhanced magnetic resonance imaging of the brain and spine is critical for establishing a diagnosis ...
Timothy K, Nguyen +2 more
openaire +2 more sources
Metastatic Melanoma With Leptomeningeal Disease [PDF]
Journal of the Advanced Practitioner in Oncology, 2021 Leptomeningeal disease in patients with melanoma historically portends a grim prognosis, with median survival measured in weeks to months. The advent of effective immunotherapy and targeted agents may modify the outcome of such patients. This case report describes a 43-year-old patient diagnosed with stage IIIa BRAF-positive cutaneous melanoma in 2012 ...
Marinova, Amanda M. +4 more
openaire +2 more sources