Results 31 to 40 of about 5,255,382 (240)
Challenges and Advances in Diagnosis and Treatment of Leptomeningeal Disease (LMD)
Frontiers in Oncology, 2022 Leptomeningeal disease (LMD) is a devastating category of CNS metastasis with a very poor prognosis and limited treatment options. With maximal aggressive therapy, survival times remain short and, without treatment, prognosis is measured in weeks.
Sherise D. Ferguson +3 more
doaj +1 more source
Atypical central neurocytoma with leptomeningeal dissemination: a case report
Journal of the Egyptian National Cancer Institute, 2020 Background Central neurocytomas represent 0.25–0.5% of all intracranial tumors in adults. Leptomeningeal spread is uncommon, and the exact incidence of meningeal spread is unknown due to sparse literature.
Shikha Goyal +5 more
doaj +1 more source
, 2023 A 31-year-old woman with transthyretin (TTR) amyloidosis secondary to a Thr60Ala mutation developed recurrent stroke-like episodes with fluctuating mental status. Evaluation for stroke and seizures was unrevealing.
Fayerman, Raisy N. +8 more
core +1 more source
Frontiers in Oncology, 2022 ObjectiveTo examine the association between Karnofsky Performance Status (“KPS”) and brain-specific progression-free survival (“bsPFS”) among patients with breast cancer brain metastases (“BCBrM”).MethodsUsing a previously compiled retrospective cohort ...
Mark Freeman +4 more
doaj +1 more source
Leptomeningeal disease in histone-mutant gliomas
Neuro-Oncology Advances, 2023 Abstract Background The 2016 WHO classification described a subtype of midline gliomas harboring histone 3 (H3) K27M alterations, and the 2021 edition added a new subtype of hemispheric diffuse gliomas with H3 G34R/V mutations.
Maria Diaz +11 more
openaire +2 more sources
F1000Research, 2022 Background: Leptomeningeal metastasis is an infrequent form of cancer expression, and it has a poor prognosis due to its torpid evolution and its challenging diagnosis.
Liliana Rodríguez-Kadota +7 more
doaj +1 more source
Susac's syndrome: Leptomeningeal enhancement on 3D FLAIR MRI
, 2016 BACKGROUND Contrast-enhanced (ce) fluid-attenuated inversion recovery magnetic resonance imaging (FLAIR MRI) has recently been shown to identify leptomeningeal pathology in multiple sclerosis.
Engisch, Renate +7 more
core +1 more source
Leptomeningeal Carcinomatosis: Easy to Miss
, 2017 Leptomeningeal carcinomatosis is a devastating condition with very poor prognosis. With advances in cancer treatment leading to improved survival in solid tumours, the incidence of ante-mortem diagnosis of leptomeningeal carcinomatosis is likely to rise.
K Das, A Sekhar, S Biswas, B Corbo
core +1 more source
Multiple myeloma with simultaneous cutaneous and central nervous system involvement
Clinical Case Reports, 2018 Key Clinical Message Cutaneous involvement in multiple myeloma is an extremely rare occurrence that is underrecognized and akin CNS involvement, typically occurs late in the disease course, and is associated with an aggressive biology.
James Nguyen, Hani Hassoun
doaj +1 more source
Visual loss as the initial manifestation of an ignored disseminated prostate cancer: A case report
American Journal of Ophthalmology Case Reports, 2022 Purpose: To present a rare case of advanced disseminated prostate cancer with bilateral visual loss as the initial manifestation of the disease. Observations: A 55-year-old man referring progressive visual blurring for the last 6 months and painless ...
Alejandra B. Miranda +3 more
doaj +1 more source