Results 21 to 30 of about 5,255,382 (240)

Leptomeningeal Carcinomatosis: A Rare Complication of Metastatic Gastric Cancer [PDF]

, 2023
Leptomeningeal disease, also known as leptomeningeal carcinomatosis, occurs when cancer metastasizes to the meninges. This rare complication is associated with a poor prognosis.
Bhardwaj, Sharonlin, Wu, Phillis, Lai, Steven Y, Phillis Wu, Sharonlin Bhardwaj, Steven Y Lai   +5 more
core   +1 more source

Multiple Cranial Neuropathies as the Presenting Sign in a Patient with Metastatic BRAF-Mutated Lung Adenocarcinoma with Leptomeningeal Involvement

Case Reports in Oncology, 2020
Leptomeningeal carcinomatosis accounts for only 4% of cases of multiple cranial neuropathies. Here, we report the case of a patient who presented with multiple synchronous cranial neuropathies.
Bailey Gleason Fitzgerald, Michael Grant, Gbambele Kone, Huned Patwa, Michal Rose   +4 more
doaj   +1 more source

CT and MRI findings in leptomeningeal melanocytosis

Radiology Case Reports, 2020
Leptomeningeal melanocytosis is a rare cause of seizure in the pediatric population. Shown here is a case of this disease in a 9-year-old male who presented with seizures and minor trauma.
Ferzana A. Hossain, BS, Hector J. Marquez, MD, Daniel L. Veltkamp, MD, Sophia Q. Xie, MD, Laura J. Klesse, MD, PhD, Charles F. Timmons, MD, PhD, Cory M. Pfeifer, MD, MS   +6 more
doaj   +1 more source

Iatrogenic Leptomeningeal Carcinomatosis Following Craniotomy for Resection of Metastatic Serous Ovarian Carcinoma: A Systematic Literature Review and Case Report

Frontiers in Surgery, 2022
Metastasis of ovarian carcinoma to the central nervous system occurs in <2% of cases and classically localizes within the brain parenchyma. Moreover, leptomeningeal spread of these tumors is an exceedingly rare phenomenon.
Brittany M. Stopa, Joshua A. Cuoco, Joshua A. Cuoco, Joshua A. Cuoco, Srijan Adhikari, Srijan Adhikari, Srijan Adhikari, Douglas J. Grider, Douglas J. Grider, Cara M. Rogers, Cara M. Rogers, Cara M. Rogers, Eric A. Marvin, Eric A. Marvin, Eric A. Marvin   +14 more
doaj   +1 more source

Epidemiology of brain metastases and leptomeningeal disease [PDF]

Neuro-Oncology, 2021
Abstract Brain metastases affect a significant percentage of patients with advanced extracranial malignancies. Yet, the incidence of brain metastases remains poorly described, largely due to limitations of population-based registries, a lack of mandated reporting of brain metastases to federal agencies, and historical difficulties ...
Nayan, Lamba, Patrick Y, Wen, Ayal A, Aizer   +2 more
openaire   +2 more sources

Histone-mutant glioma presenting as diffuse leptomeningeal disease

, 2021
Glioblastoma multiforme is the most common malignant primary brain tumor in adults. Histone H3 mutations have been identified in pediatric and adult gliomas, with H3K27M mutations typically associated with a posterior fossa midline tumor location and ...
Uchenna Okakpu, Faraze Niazi, Tanvi Nadkarni, Melanie Ward, Ion Prisneac, Kimberly Hamilton, Rudolph J Castellani, Ugur Sener   +7 more
core   +1 more source

Systemic and Craniospinal Rosai Dorfman Disease with Intraparenchymal, Intramedullary and Leptomeningeal Disease [PDF]

, 2021
Rosai Dorfman disease is a rare histiocytic disorder of over-production of non-Langerhans histiocytes, which typically manifests with massive lymphadenopathy and sinonasal involvement. We report a rare case of systemic and disseminated craniospinal Rosai
Cha, Soonmee, Bollen, Andrew, Theodosopoulos, Philip, Solomon, David, Li, Yi, Sloan, Emily, Soonmee Cha, Andrew Bollen, Philip Theodosopoulos, Emily Sloan, Yi Li, Yi Li MD, David Solomon   +12 more
core   +1 more source

Moyamoya Disease Misdiagnosed As Leptomeningeal Metastases [PDF]

Journal of Clinical Oncology, 2012
Contains fulltext : 108739.pdf (Publisher’s version ) (Open Access)
Heijmen, L., Heijmen, L., van Dijk, E.J., Goraj, B.M., van Laarhoven, H.W.M.   +4 more
openaire   +3 more sources

Salvage Therapy With Selpercatinib for RET-Rearranged NSCLC With Pralsetinib-Related Pneumonitis and Leptomeningeal Disease: A Case Report

JTO Clinical and Research Reports, 2023
Selpercatinib and pralsetinib are RET inhibitors with substantial activity in advanced RET-rearranged NSCLC. We present a case of pralsetinib-related pneumonitis and leptomeningeal and brain metastases progression during treatment suspension for ...
Paolo D. d'Arienzo, MD, MRCP, Niamh Cunningham, MBBS, BSc, MRCP, Hazel O’Sullivan, MBBchBAO, MRCPI, Charlotte Grieco, MBBS, MRCP, Virjen Patel, MbChB, BSc, FRCR, Sanjay Popat, PhD, FRCP   +5 more
doaj   +1 more source

Diagnostic and Therapeutic Updates in Leptomeningeal Disease

Current Oncology Reports, 2023
Abstract Purpose of Review Leptomeningeal disease (LMD) is a devastating complication of advanced metastatic cancer associated with a poor prognosis and limited treatment options. This study reviews the current understanding of the clinical presentation, pathogenesis, diagnosis, and treatment ...
Meaghan A. Roy-O’Reilly, Tyler Lanman, Amber Ruiz, David Rogawski, Brian Stocksdale, Seema Nagpal   +5 more
openaire   +2 more sources