Results 91 to 100 of about 1,344,206 (319)

Emergence of modular structure in a large-scale brain network with interactions between dynamics and connectivity

open access: yesFrontiers in Computational Neuroscience, 2010
A network of 32 or 64 connected neural masses, each representing a large population of interacting excitatory and inhibitory neurons and generating an EEG / MEG like output signal, was used to demonstrate how an interaction between dynamics and ...
Cornelis Jan Stam   +3 more
doaj   +1 more source

A Metamorphic Lesion [PDF]

open access: yesGastroenterology, 2009
Rolanda, C, Gonçalves, R, Macedo, G
openaire   +4 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CEREBRAL LESIONS. [PDF]

open access: yesThe Lancet, 1876
n ...
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

SLAP Lesion with Supraglenoid Labral Cyst causing Suprascapular Nerve Compression: A case report

open access: yes, 2012
We present a case of left suprascapular nerve palsy in a 39-year-old female secondary to compression from a large ganglion cyst. She presented with a two month history of left posterior shoulder pain which affected her work and disturbed her sleep ...
Bryan Y Tan, Lee KT
core   +1 more source

Skin lesion segmentation using two-phase cross-domain transfer learning framework

open access: yes, 2023
Background and Objective Deep learning (DL) models have been used for medical imaging for a long time but they did not achieve their full potential in the past because of insufficient computing power and scarcity of training data.
Karri, Meghana   +2 more
core   +1 more source

Temporal discrimination of sub- and suprasecond time intervals: a voxel-based lesion mapping analysis

open access: yesFrontiers in Integrative Neuroscience, 2011
We used voxel-based lesion-symptom mapping (VLSM) to determine which brain areas are necessary for discriminating time intervals above and below one second.
Cynthia M Gooch   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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