Results 81 to 90 of about 1,807,517 (362)

Reproducibility of Lesion Count in Various Subregions on MRI Scans in Multiple Sclerosis

Frontiers in Neurology, 2022
PurposeLesion number and burden can predict the long-term outcome of multiple sclerosis, while the localization of the lesions is also a good predictive marker of disease progression. These biomarkers are used in studies and in clinical practice, but the
Bence Bozsik, Eszter Tóth, Ilona Polyák, Fanni Kerekes, Nikoletta Szabó, Krisztina Bencsik, Péter Klivényi, Zsigmond Tamás Kincses, Zsigmond Tamás Kincses   +8 more
doaj   +1 more source

CoactSeg: Learning from Heterogeneous Data for New Multiple Sclerosis Lesion Segmentation [PDF]

arXiv, 2023
New lesion segmentation is essential to estimate the disease progression and therapeutic effects during multiple sclerosis (MS) clinical treatments. However, the expensive data acquisition and expert annotation restrict the feasibility of applying large-scale deep learning models.
arxiv  

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Pain relief following spinal lesion treatment with stereotactic radiosurgery: Clinical experience in 65 cases

Journal of Medical Sciences, 2015
Background: This study determines the pain-reducing effect of CyberKnife radiosurgery in the treatment of spinal lesions. Materials and Methods: We evaluated the clinical outcomes of patients treated with CyberKnife radiosurgery for spinal lesions in 65 ...
Shih-Wei Hsu, Hsing-Lung Chao, Kuen-Tze Lin, Yu-Ching Chou, Cheng-Hsiang Lo, Shih-Yu Lee, Wen-Yen Huang, Chun-Shu Lin, Chien-Min Lin, Chao-Yueh Fan, Da-Tong Ju   +10 more
doaj   +1 more source

Modeling the Intra-class Variability for Liver Lesion Detection using a Multi-class Patch-based CNN

, 2017
Automatic detection of liver lesions in CT images poses a great challenge for researchers. In this work we present a deep learning approach that models explicitly the variability within the non-lesion class, based on prior knowledge of the data, to ...
Amitai, Michal, Diamant, Idit, Frid-Adar, Maayan, Goldberger, Jacob, Greenspan, Hayit, Klang, Eyal   +5 more
core   +1 more source

CEREBELLAR LESION [PDF]

The Journal of Nervous and Mental Disease, 1921
n ...
openaire   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

A case of Beauveria bassiana keratitis confirmed by internal transcribed spacer and LSU rDNA D1–D2 sequencing

New Microbes and New Infections, EarlyView., 2014
Abstract We describe a case of fungal keratitis due to Beauveria bassiana in a farmer with Fuchs' dystrophy, treated with amphotericin B. Surgery with penetrating keratoplasty was necessary to resolve the lesions. Susceptibility testing and molecular sequencing permitted the identification and treatment of this rare aetiological agent of invasive ...
M. Ligozzi, L. Maccacaro, M. Passilongo, E. Pedrotti, G. Marchini, R. Koncan, G. Cornaglia, A. R. Centonze, G. Lo Cascio   +8 more
wiley   +1 more source

Effectiveness of endoscopic papillectomy with stent placement in pancreatic and bile ducts for treating duodenal papillary adenoma: a retrospective study

BMC Gastroenterology
Background Duodenal papillary adenoma, a potentially malignant benign tumor is primarily treated with endoscopic papillectomy. Despite its efficacy, endoscopic papillectomy has a high complication rate. This study investigates whether pancreatic duct and
Jiani Jiang, Fujing Lv, Chuyan Chen, Wei Jiang   +3 more
doaj   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source