Results 31 to 40 of about 1,864,013 (297)

Evaluating the potential of phenotypic age to enhance cardiovascular risk prediction over chronological age in the UK Biobank

Scientific Reports
Phenotypic age acceleration (PhenoAgeAccel) is a novel biological indicator estimates an individual’s mortality risk. The primary aim of this study was to evaluate the association between PhenoAge and PhenoAgeAccel with incident cardiovascular diseases ...
Kristine J. S. Kwan, Shi-Shuai Xie, Hai-Lei Li, Xue-Guang Lin, Yi-Jie Lu, Bo Chen, Kai-Xin Ge, Shu-Ya Tang, Hui Zhang, Shuai Jiang, Jing-Dong Tang   +10 more
doaj   +1 more source

Clinical and pathological characteristics of and predictive model for colorectal neuroendocrine tumors

Heliyon
Background: The incidence of colorectal neuroendocrine tumors (NETs) is increasing, causing a social burden. At present, there is no specific prognostic model for colorectal NETs.
Jiuyue Ma, Xiaoqian Ma, Jie Xing, Ruyun Song, Yang Zhang, Mo Liu, Shuilong Guo, Qian Zhang, Jing Wu   +8 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Triglyceride–glucose index in the associations between chronic low-grade inflammation and carotid intima-media thickness: mediation and effect-modification across triglyceride–glucose strata

BMC Cardiovascular Disorders
Aims Atherosclerosis is established as a chronic inflammatory disease, yet the potential mediating role of glucose and lipid metabolism in inflammation-driven atherogenesis has not been fully elucidated.
Xueguang Lin, Shishuai Xie, Bingbing Pu, Zheyu Wang, Hui Zhang, Yunxia Li, Jingdong Tang, Bo Yu, Shuai Jiang   +8 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

ACSL1 Aggravates Thromboinflammation by LPC/LPA Metabolic Axis in Hyperlipidemia Associated Myocardial Ischemia‐Reperfusion Injury

Advanced Science
Acute myocardial infarction (AMI) is associated with well‐established metabolic risk factors, especially hyperlipidemia and obesity. Myocardial ischemia‐reperfusion injury (mIRI) significantly offsets the therapeutic efficacy of revascularization ...
Shuai Jiang, Xueguang Lin, Bo Chen, Gang Chen, Kristine J.S. Kwan, Jing Liu, Qi Sun, Jie Wang, Yijie Lu, Jindong Tong, Ying Deng, Bo Yu, Jingdong Tang   +12 more
doaj   +1 more source

Ameliorating effect of Withania somnifera root extract in Escherichia coli–infected broilers

Poultry Science, 2020
The present study was undertaken to investigate the effect of aqueous Withania somnifera root (WSR) extract in broiler chicks experimentally infected with Escherichia coli O78 @ 107 CFU/0.5 ml intraperitoneally.
Mamta Kumari, Rajendar P. Gupta, Deepika Lather, Preeti Bagri   +3 more
doaj   +1 more source

Application of 68Ga-citrate PET/CT for differentiating periprosthetic joint infection from aseptic loosening after joint replacement surgery

Bone & Joint Research, 2022
Aims: We aimed to evaluate the utility of 68Ga-citrate positron emission tomography (PET)/CT in the differentiation of periprosthetic joint infection (PJI) and aseptic loosening (AL), and compare it with 99mTc-methylene bisphosphonates (99mTc-MDP) bone ...
Tingting Xu, Yalan Zeng, Xiao Yang, Guangfu Liu, Taiyong Lv, Hongbin Yang, Fei Jiang, Yue Chen   +7 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Skin disorder diagnosis with ambiguity reduction assisted by lesion color adaptation

AIMS Electronics and Electrical Engineering, 2019
A smart phone application based on a low complexity image processing technique and a novel fuzzy-like classification method are presented for skin disorder diagnosis. The proposed classification method takes into consideration the size and color features
Nikos Petrellis
doaj   +1 more source