Results 41 to 50 of about 2,984 (199)
Immunity, Inflammation and Disease, 2021 Letermovir prophylaxis in allogeneic hematopoietic cell transplant recipients significantly reduces the incidence of clinically significant cytomegalovirus infection. However, breakthrough infections still occur despite adequate prophylaxis.
Léna Royston +5 more
doaj +1 more source
Cytomegalovirus drug resistance mutations in transplant recipients with suspected resistance [PDF]
, 2023 Resistant CMV infections are challenging complications after SOT and HSCT. Prompt recognition of ARMs is imperative for appropriate therapy. 108 plasma samples from 96 CMV + transplant recipients with suspected resistance were analysed in CNM in a ...
Gonzalez-Jimenez, Irene +2 more
core +1 more source
Isolation and characterization of the herpes simplex virus 1 terminase complex [PDF]
, 2013 During herpes simplex virus 1 (HSV-1) infection, empty procapsids are assembled and subsequently filled with the viral genome by means of a protein complex called the terminase, which is comprised of the HSV-1 UL15, UL28, and UL33 proteins.
Heming, Jason D +3 more
core +2 more sources
Letermovir Prophylaxis for Cytomegalovirus [PDF]
New England Journal of Medicine, 2018 Marty and colleagues (Dec. 21 issue)1 found that letermovir prophylaxis after hematopoietic-cell transplantation resulted in a lower risk of clinically significant cytomegalovirus (CMV) infection than placebo. This trial shows that a prophylactic agent can provide meaningful benefit after hematopoietic-cell transplantation, without considerable ...
L'Huillier, Arnaud +2 more
openaire +7 more sources
Clinical Infection in Practice, 2020 Reported is a case of cytomegalovirus ventriculitis on a background of HIV infection. Sequencing demonstrated viral mutations conferring resistance to available therapies.
Andrew Bosworth +7 more
doaj +1 more source
Antiviral therapy defiant mixed viral retinitis post hematopoietic allogeneic stem cell transplant
Clinical Case Reports, 2023 Cytomegalovirus (CMV) retinitis is an uncommon presentation post allogeneic transplant and can be vision‐threatening. Our case demonstrates the occurrence of polymerase chain reaction (PCR) proven mixed viral retinitis (cytomegalovirus and varicella ...
Nadia Gabarin +5 more
doaj +1 more source
BMJ Open, 2023 Introduction Chronic cytomegalovirus (CMV) infection is very frequent in people living with HIV (PLWH). High anti-CMV IgG titres, which may be linked to transient CMV replication, have been associated with earlier mortality, CD8 T-cell expansion, lower ...
Jean-Pierre Routy +15 more
doaj +1 more source
Cost-Effectiveness Analysis Of The Prevention And Treatment Of Cytomegalovirus (CMV) Infections After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) In Adults [PDF]
, 2019 Целта на изследването е да се представи моделиране на локални данни за разходи и здравни ползи на алтернативните антивирусни терапии за профилактика и лечение на цитомегаловирус (CMV) - серопозитивни пациенти след алогенна трансплантация на хемопоетични ...
Gavrilova, Anna +3 more
core +2 more sources
Current Perspectives on the Management of Herpesvirus Infections in Solid Organ Transplant Recipients [PDF]
, 2023 Solid organ transplant recipients (SOTRs) are at high risk of human herpesvirus (HHV)-related morbidity and mortality due to the use of immunosuppressive therapy.
Baan, Carla C. +7 more
core +2 more sources
Anti-CMV therapy, what next? A systematic review
Frontiers in Microbiology, 2023 Human cytomegalovirus (HCMV) is one of the main causes of serious complications in immunocompromised patients and after congenital infection. There are currently drugs available to treat HCMV infection, targeting viral polymerase, whose use is ...
Claire Gourin +4 more
doaj +1 more source