Results 71 to 80 of about 3,523 (219)

Mendelian Randomization Identifies the Potential Causal Impact of Dietary Patterns on Circulating Blood Metabolites [PDF]

, 2021
Nutrition plays an important role in the development and progress of several health conditions, but the exact mechanism is often still unclear. Blood metabolites are likely candidates to be mediating these relationships, as their levels are strongly ...
Andres Metspalu, Andres Metspalu, Hanna-Kristel Valge, James F. Wilson, James F. Wilson, Krista Fischer, Krista Fischer, Nele Taba, Nele Taba, Nicola Pirastu, Tõnu Esko, Tõnu Esko   +11 more
core   +3 more sources

Intestinal and Multivisceral Transplantation: Where We Stand Today

Pediatric Transplantation, Volume 30, Issue 1, January 2026.
ABSTRACT Intestinal and multivisceral transplantation has evolved from an experimental to a life‐saving procedure for children and adults with complications of gut failure (GF). Suboptimal long‐term outcomes of transplant elicit recent advances in surgical and medical gut rehabilitation along with the introduction of glucagon‐like peptide‐2 (GLP‐2 ...
Mohamed Maklad, Mohammed Osman, Mariam Ismail, Tetsuya Tajima, Kadakkal Radhakrishnan, Masato Fujiki   +5 more
wiley   +1 more source

Stewardship of Molecular Diagnostics in Transplant Viral Infections

Transplant Infectious Disease, Volume 28, Issue 1, January/February 2026.
ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden, David Reynoso, Reema Mathew, Michael Loeffelholz   +3 more
wiley   +1 more source

Letermovir Effectively Prevents Cytomegalovirus Infection in Patients with Aplastic Anemia After Hematopoietic Stem Cell Transplantation: A Real-World Retrospective Cohort Study

Infectious Diseases and Therapy
Introduction In this single-center retrospective cohort study, we investigated the efficacy of letermovir in preventing Cytomegalovirus (CMV) infection in patients with aplastic anemia (AA) who have undergone allogeneic hematopoietic stem cell ...
Yuling Zhang, Xiaowei Chen, Ming Zhou, Yuping Zhang, Cunte Chen, Ruiqing Zhou, Yumiao Li, Fangfang Yang, Shilin Xu, Caixia Wang, Wei Zhou, Tingfen Deng, Shiyi Pan, Wenjian Mo, Shunqing Wang   +14 more
doaj   +1 more source

Effect of antivirals on clinical and lab-adapted human cytomegalovirus strains using induced pluripotent stem cell-derived human neural models [PDF]

Human cytomegalovirus (CMV) infections can cause severe neurological complications, particularly in newborns and immunocompromised patients. Children affected with congenital CMV infection may develop long-term neurological damage and intellectual ...
Calitz, Carlemi, Cornelissen, Marion, Freeze, Eline, Kampen, Jeroen Van, Koen, Gerrit, Korsten, Joep, Molenkamp, Richard, Mulder, Lance A., Pajkrt, Dasja, Schotting, Amber J., Sridhar, Adithya, Vieira da Sá, Renata, Wolthers, Katja C., Zorgdrager, Fokla   +13 more
core   +1 more source

Baseline Cytomegalovirus Immunoglobulin G Levels Predict Reactivation in Patients With Multiple Myeloma Receiving Elranatamab

eJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Background The cumulative incidence and risk of cytomegalovirus (CMV) reactivation in patients with relapsed/refractory multiple myeloma (RRMM) receiving elranatamab remain unclear. Methods We retrospectively analyzed RRMM patients treated with elranatamab to assess cumulative incidence and risk factors for CMV reactivation.
Ukyo Kondo, Taku Kikuchi, Shotaro Sugita, Miyu Watanabe, Chiaki Matsumoto, Moe Nomura‐Yogo, Kodai Kunisada, Kota Sato, Tomomi Takei, Mizuki Ogura, Yu Abe, Osamu Hosoya, Tadao Ishida, Nobuhiro Tsukada   +13 more
wiley   +1 more source

New Treatment Options for Refractory/Resistant CMV Infection

Transplant International, 2023
Despite advances in monitoring and treatment, cytomegalovirus (CMV) infections remain one of the most common complications after solid organ transplantation (SOT).
Carla Simone Walti, Nina Khanna, Robin K. Avery, Ilkka Helanterä   +3 more
doaj   +1 more source

Diseño, síntesis y caracterización estructural de compuestos derivados de 2-amino-propano-1,3-diol potencialmente activos como antivirales [PDF]

, 2019
Los adenovirus (AdV) son virus eucariotas con 36000 pares de bases, producen infecciones que son muy comunes y se dan durante todo el año. Las poblaciones susceptibles a la infección por adenovirus (AdV) incluyen niños, pacientes inmunocomprometidos y ...
Muriana Camacho, Claudia
core  

Post‐Transplant Cyclophosphamide for Graft‐Versus‐Host Disease Prophylaxis in Pediatric Stem Cell Transplantation

Pediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
ABSTRACT Graft‐Versus‐Host disease (GVHD) is a leading contributor to morbidity and mortality following stem cell transplantation (SCT). Current GVHD prevention methods utilize a combination of immunosuppressive drugs to prevent injury to host tissues.
Aaron E. Fan, Wilson Andres Vasconez, Ramya Ramakrishnan, Priti Tewari, Amanda Olson, Elizabeth J. Shpall, Irtiza N. Sheikh   +6 more
wiley   +1 more source

A Novel Triple-Fluorescent HCMV Strain Reveals Gene Expression Dynamics and Anti-Herpesviral Drug Mechanisms

Frontiers in Cellular and Infection Microbiology, 2021
Human Cytomegalovirus (HCMV) infection may result in severe outcomes in immunocompromised individuals such as AIDS patients, transplant recipients, and neonates.
Ulfert Rand, Tobias Kubsch, Bahram Kasmapour, Bahram Kasmapour, Luka Cicin-Sain, Luka Cicin-Sain, Luka Cicin-Sain, Luka Cicin-Sain   +7 more
doaj   +1 more source