Results 111 to 120 of about 192,079 (155)

Pharmacokinetics and bio-distribution of differently functionalized Carbon nanotube in Zebrafish, Danio rerio. [PDF]

Discov Nano
Kumari K, Pathan MA, Surendran S, Varghese T, Poojary N, Singh AL, Kranthirekha M, Halim AFMF, Poinern GEJ, Fawcett D, Sharma R.   +10 more
europepmc   +1 more source

Development of whole virion inactivated Kyasanur Forest Disease vaccine candidate and its preclinical safety and efficacy evaluation. [PDF]

Front Immunol
Sunagar R, Penta N, Mohandas S, Cheruvara R, Bonda RL, Algangula P, Meena VK, Kumar S, Nimmagadda S, Narayan J, Gupta N, Yadav PD, Kanakasapapathy AK.   +12 more
europepmc   +1 more source

A dynamic pharmacometric framework defining the relationship between ivermectin exposure and mosquito lethality

Hoglund RM, Kobylinski KC, Jittamala P, Hanboonkunupakarn B, Wamaket N, Sriwichai P, Phasomkusolsil S, White NJ, Day NP, Tarning J.   +9 more
europepmc   +1 more source

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The lethal heat dose for 50% primary human fibroblast cell death is 48 °C

Archives of Dermatological Research, 2021
Understanding the effect of heat on skin cells is important for the prevention of burn injury. Knowledge of the heat dose required to kill cells can be used to study the cellular mechanisms involved in thermal injury cell death, to assist with the development of novel burn treatments. In this study, primary human skin dermal fibroblasts were exposed to
Elissa Henderson, Margaretha Kempf, Charlotte Yip, Lisa Davenport, Emily Jones, Sara Kong, Ella Pearson, Anastasia Kearns, Leila Cuttle   +8 more
openaire   +5 more sources

Effect of Intraventricular Administration of Antisomatostatin γ-Globulin on the Lethal Dose-50 of Strychnine and Pentobarbital in Rats*

Endocrinology, 1978
Effects of intraventricular injection of sheep anti-somatostatin gamma-globulin (anti-SSG) on strychnine-induced seizures, strychnine LD50, and pentobarbital LD50 were examined in male rats under light ether anesthesia. Ten microliters of anti-SSG given 2 h earlier significantly decreased the duration of strychnine-induced seizures as compared with ...
K, Chihara, A, Arimura, M, Chihara, A V, Schally   +3 more
openaire   +2 more sources

Determination of acute lethal dose 50 (LD50) of uranyl nitrate in male swiss albino mice

Research Journal of Pharmacy and Technology, 2018
Evaluation of LD50 is the foremost step in the assessment of toxicity of a substance. The present study was designed to determine the acute LD50 of uranyl nitrate via intraperitoneal route in male swiss albino mice. The selected single doses of uranyl nitrate from the pilot study conducted were 64, 32, 16, 8, 4mg/kg bdwt.
Sangeetha P. Vijayan, P. D. Rekha, U. Dinesh, A.B. Arun   +3 more
openaire   +1 more source

The causative agent of bradzot's disease is CL. results of laboratory determination of 50% and 100% lethal doses (LD50 and LD100) of oedematiens strain

ACADEMICIA: An International Multidisciplinary Research Journal, 2021
AbstractThe article describes the results of detection of 50% (ID50) and 100% (ID100) lethal doses of the pathogen in guinea pigs infected with one-day Cl.Oedematiens culture grown in Kitt-Tarottsi nutrient medium from pathological samples from sheep infected with bradzot.
R.M. Uraqova, H.S. Salimov
openaire   +1 more source

[Ciradian variation in the lethal dose 50 of mercuric chloride in mice].

Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie, 1982
If circadian variations in tolerance to drugs have been often demonstrated, such observations about heavy metals are still very scarce. The present study proposes to determine if circadian variations occur in the tolerance of Mice to single lethal dose of mercuric chloride. 360 female Mice, kept in cages on a 8.00 - 20.00 L/D cycle, receive I.P.
J, Cambar, J C, Cal
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Acute Toxicity (Lethal Dose 50 calculation) Of Diarrhea stop Herbal Product In Rats

Yemen University Journal
Introduction: Diarrhea is a common gastrointestinal disorder that significantly impacts health and quality of life worldwide. Herbal medicine offers a promising approach to managing diarrhea, combining traditional knowledge with modern pharmacological evidence.
Dr. Hussien O. Kadi, Ismail Hamoud Ali Al-geobri, Abdulmalek Abu-Donia, Abdullalh Alharzi   +3 more
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The relationship between faecal egg count reduction and the lethal dose 50% in the egg hatch assay and larval development assay

Veterinary Parasitology, 1998
The relationship between resistance detected in the faecal egg count reduction test (FECRT) and the lethal dose 50% (LD50) in the egg hatch assay (EHA) for benzimidazoles (BZs) and a larval development assay (LDA) for BZs, levamisole (LEV) and ivermectin (IVM) was examined on 13 sheep farms and 12 goat farms in Denmark. Out of 10 farms where resistance
Dangolla, A, Bjørn, H, Maingi, N
openaire   +2 more sources