Results 91 to 100 of about 5,585,699 (313)

Identifying Optimum Herbicide Mixtures to Manage and Avoid Fenoxaprop-p-Ethyl Resistant Phalaris minor in Wheat [PDF]

open access: yesPlanta Daninha, 2016
Use of herbicide mixtures has been advocated as most effective strategy for avoidance and management of herbicide resistant weeds. Effect of twelve selected treatments of four herbicides (clodinafop-propargil, metribuzin, pinoxaden and sulfosulfuron) two-
T. ABBAS   +3 more
doaj   +2 more sources

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Optimal designs for dose-response models with restricted design spaces [PDF]

open access: yes
In dose response studies, the dose range is often restricted due to concerns over drug toxicity and/or efficacy. We present restricted and unrestricted interval locally optimal designs with respect to a very general class of optimality criteria for ...
Zhu, Wei   +2 more
core  

Lethal and sub-lethal yessotoxin dose-induced morpho-functional alterations in intraperitoneal injected Swiss CD1 mice

open access: yes, 2004
Histological and immunocytochemical investigations were performed on different organs (brain, duodenum and thymus) of mice following lethal (420 mug/kg) or sublethal (10 mug/kg) intraperitoneal injection of yessotoxin (YTX).
FRANCHINI, Antonella   +3 more
core   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

The protective effect of polarized, incoherent, polychromatic light on white mice infected with influenza A virus

open access: yesJournal of Education, Health and Sport, 2017
Under the influence of polarized light, the reproduction of the influenza A virus in the mice has been slowed. The survival rate of mice infected with a lethal dose of influenza A virus was 50%, compared to the control group.
N. A. Mamedaliev, V. A. Divocha
doaj   +3 more sources

Effects of the European hornet ( Vespa crabro Linnaeus 1761) crude venom on its own species

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2013
Background Lethal dose 50% is a classical index of toxicity that usually employs small rodents as experimental animals. Therefore, scarce data are available on the effects of venom on invertebrates, particularly the impact of wasp venom on its own ...
Jerzy Nadolski
doaj   +1 more source

The new algorithm for calculation of median lethal dose (LD 50 ) and effective dose fifty (ED 50 ) of Micrarus fulvius venom and anti-venom in mice

open access: yesInternational Journal of Veterinary Science and Medicine, 2016
Background One million people throughout the world are bitten each year by poisonous snakes. Of this, one‐tenth died and three‐tenth suffer some forms of disabilities. In view of this, anti‐snake venoms are currently being developed against viper and colubrid snake venoms using mice.
openaire   +3 more sources

The murine intravenous median lethal dose (LD50) of the haemotoxic snake venoms used in this study.

open access: yes, 2021
The murine intravenous median lethal dose (LD50) of the haemotoxic snake venoms used in this study.
Robert A. Harrison (7062377)   +6 more
core   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

open access: yesFEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto   +14 more
wiley   +1 more source

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