Results 91 to 100 of about 346,940 (303)
Under the influence of polarized light, the reproduction of the influenza A virus in the mice has been slowed. The survival rate of mice infected with a lethal dose of influenza A virus was 50%, compared to the control group.
N. A. Mamedaliev, V. A. Divocha
doaj +3 more sources
Effects of the European hornet ( Vespa crabro Linnaeus 1761) crude venom on its own species
Background Lethal dose 50% is a classical index of toxicity that usually employs small rodents as experimental animals. Therefore, scarce data are available on the effects of venom on invertebrates, particularly the impact of wasp venom on its own ...
Jerzy Nadolski
doaj +1 more source
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Disturbance-effect relationships applied in an integral Ecological Risk Analysis for the human use of the North Sea [PDF]
The relationship between the intensity of seven types of human based disturbances and their resulting effects on survival and reproduction of 30+ species were described as a function of increased mortality or reduced reproduction in the report of Jak et ...
Karman, C.C. +2 more
core +1 more source
The dose makes the poison: have “field realistic” rates of exposure of bees to neonicotinoid insecticides been overestimated in laboratory studies? [PDF]
Recent laboratory based studies have demonstrated adverse sub-lethal effects of neonicotinoid insecticides on honey bees and bumble bees, and these studies have been influential in leading to a European Union moratorium on the use of three neonicotinoids,
BARON G L +16 more
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
A gorilla adenovirus-based vaccine against Zika virus induces durable immunity and confers protection in pregnancy [PDF]
The teratogenic potential of Zika virus (ZIKV) has made the development of an effective vaccine a global health priority. Here, we generate two gorilla adenovirus-based ZIKV vaccines that encode for pre-membrane (prM) and envelope (E) proteins (GAd-Zvp ...
Brough, Douglas E +7 more
core +1 more source
Identification of onosma visianii roots extract and purified shikonin derivatives as potential acaricidal agents against tetranychus urticae [PDF]
There is an increasing need for the discovery of reliable and eco-friendly pesticides and natural plant-derived products may play a crucial role as source of new active compounds.
Benelli, S. +7 more
core +1 more source
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Background Hypervirulent Klebsiella pneumoniae (hvKP) is emerging around the Asian-Pacific region and it is the major cause of the community-acquired pyogenic liver abscesses.
Qiucheng Shi +6 more
doaj +1 more source

