Results 81 to 90 of about 5,585,699 (313)

Acute effects of methcathinone and manganese in mice: A dose response study

open access: yesHeliyon, 2019
An intravenously injectable illicit drug made by mixing pseudoephedrine, potassium permanganate, vinegar and water, yielding methcathinone (Mcat) and manganese (Mn), induces an extrapyramidal syndrome with parkinsonism, dystonia, gait and balance ...
Andres Asser   +9 more
doaj   +1 more source

Acute paraquat poisoning: report of a survival case following intake of a potential lethal dose.

open access: yesPediatric emergency care, 2006
When properly used, paraquat (PQ) is a widely used bipyridil herbicide with a good safety record. Most cases of PQ poisoning result from intentional ingestion, with death resulting from hypoxemia secondary to lung fibrosis in moderate to severe ...
R. Dinis-Oliveira   +6 more
semanticscholar   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Characterization of food color additives and evaluation of their acute toxicity in Wistar albino rats [PDF]

open access: yesVeterinary World
Background and Aim: The use of food dyes can cause certain diseases, such as anemia and indigestion, along with other disorders, tumors, and even cancer.
D. A. Qasim, I. J. Lafta
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Using Ivermectin for treating channel catfish (Ictalurus punctatus) infected with Dollfustrema bagarii

open access: yesFisheries and Aquatic Sciences
Channel catfish (Ictalurus punctatus), an introduced species in Vietnam, is widely cultured in the Northern provinces. The off-white grub disease in Channel catfish, caused by metacercariae of Dollfustrema bagarii (Digenea: Bucephalidae) lodged in ...
Manh Duc Vu   +7 more
doaj   +1 more source

Effects of Oliveria decumbens and Ferula assa-foetida essential oils and their nanoemulsions on Mediterranean flour moth (Ephestia kuehniella) [PDF]

open access: yesIran Agricultural Research
In this study, effects of essential oils and their nanoemulsions extracted from Oliveria decumbens flowers and Ferula assa-foetida oleo-gum-resin were evaluated on late-instar larvae of the Mediterranean flour moth (Ephestia kuehniella).
Faezeh Bagheri   +2 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Two Genetically Similar H9N2 Influenza A Viruses Show Different Pathogenicity in Mice

open access: yesFrontiers in Microbiology, 2016
H9N2 Avian influenza virus has repeatedly infected humans and other mammals, which highlights the need to determine the pathogenicity and the corresponding mechanism of this virus for mammals. In this study, we found two H9N2 viruses with similar genetic
Qingtao Liu   +7 more
doaj   +1 more source

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