Results 61 to 70 of about 5,585,699 (313)

A new mathematical model for radiation cell killing mechanism: Target cumulating model [PDF]

, 2009
There are numerous mathematical or statistical models have been given out for radiation cell killing mechanism. Unfortunately, none of the model could explain the mechanism perfectly.
Xie Congyin, Zhang Li, Zhao Liang, Wu Shixiu   +3 more
core  

Median Oral Lethal Dose/Lethal concentration (LD₅₀/LC₅₀) of technical grade bromethalin in mammals and birds [4].

, 2019
Median Oral Lethal Dose/Lethal concentration (LD50/LC50) of technical grade bromethalin in mammals and birds [4].
Kathy M. Loftis (6475505), Richard Bauer (95338), Christopher R. Gregory (6475508), Sayed M. Hassan (1774987), Fern Van Sant (6475496), Rita McManamon (6475502), Paula G. Ciembor (6475511), Elizabeth W. Howerth (160660), Branson W. Ritchie (1879561), Drury Reavill (6475499), Mauricio Seguel (4244593)   +10 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The acute toxicity of 5-thio-substituted 3-(5-bromofuran-2-yl)-4-ethyl-(4H)-1,2,4-triazole derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
Aim. Research of the acute toxicity of new compounds could prevent the development of compounds with high pharmacological activity, which exhibit undesirable pharmacological properties.
E. S. Pruglo, A. I. Panasenko, E. G. Knysh   +2 more
doaj   +1 more source

Aquatain® Mosquito Formulation (AMF) for the control of immature Anopheles gambiae sensu stricto and Anopheles arabiensis: dose-responses, persistence and sub-lethal effects

Parasites & Vectors, 2014
BackgroundPersistent monomolecular surface films could benefit larval source management for malaria control by reducing programme costs and managing insecticide resistance.
O. Mbare, S. Lindsay, U. Fillinger
semanticscholar   +1 more source

Lethal dose (LD₅₀) of two individual venoms of B. moojeni snakes.

, 2019
The LD50 was determined by the intraperitoneal injection of different doses of B. moojeni venom belonging to the Bm2 and Bm4 individuals. Median lethal dose (LD50) is defined as the dose responsible for the death of 50% of the population analyzed.
Erika Sayuri Nishiduka (7377650), Alexandre Keiji Tashima (4911502), Karen de Morais-Zani (7377653), Weslei da Silva Aguiar (7377638), Anita Mitico Tanaka-Azevedo (4911499), Kathleen Fernandes Grego (7377647), Sávio Stefanini Sant’Anna (7377644), Nathália da Costa Galizio (7377641), Caroline Serino-Silva (4911520)   +8 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Non-Lethal Dose-Response Models Replace Lethal Bioassays for Predicting the Hazard of Para-Aminopropiophenone to Australian Wildlife

Animals, 2023
Para-aminopropiophenone (PAPP) is a potent methaemoglobin (MetHb) forming agent used for the lethal control of exotic carnivores and mustelids. To assess the sensitivity of Australian wildlife to PAPP we developed an in vivo assay that did not use death ...
Clive A. Marks, Lee Allen, Heli Lindeberg   +2 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Assessment of the Antinociceptive, Anti-Inflammatory, and Acute Toxicity Effects of Solanum Dulcamara Essential Oil in Male Mice

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2020
BACKGROUND AND OBJECTIVE: Pain is a complex set of unpleasant sensory, emotional, and cognitive experiences that are relieved with synthetic and herbal remedies. Of course, medicinal plants are more important than chemical drugs due to fewer side effects.
AR Fallahzadeh, S Mohammadi
doaj