Results 51 to 60 of about 5,585,699 (313)

Determination of Median Lethal Dose of Combination of Endosulfan and Cypermethrin in Wistar Rat

Toxicology International, 2013
The present study was designed to determine the lethal dose 50 (LD 50 ) of combination of cypermethrin, a pyrethroid, and endosulfan, an organochlorine compound in Wistar rats. LD 50 is the amount (dose) of a chemical, calculated as per the concentration
J. Raj, M. Chandra, T. Dogra, M. Pahuja, A. Raina   +4 more
semanticscholar   +1 more source

Airborne Infection with Bacillus anthracis—from Mills to Mail

Emerging Infectious Diseases, 2004
The lack of identified exposures in 2 of the 11 cases of bioterrorism-related inhalation anthrax in 2001 raised uncertainty about the infectious dose and transmission of Bacillus anthracis. We used the Wells-Riley mathematical model of airborne infection
Kevin P. Fennelly, Amy L. Davidow, Shelly L. Miller, Nancy Connell, Jerrold J. Ellner   +4 more
doaj   +1 more source

Median lethal dose (LD₅₀) and 90% lethal dose (LD₉₀) with 90% confidence limits of H. armigera fed with Ar1b-HearNPV, HZ8-HearNPV and wt-HearNPV.

, 2015
a, b Lethal doses were determined by probit in SPSS 15.0.c The intercepts of the equations of log (dose)—mortality (probit) were calculated based on the slopes and LD50 given by SPSS 15.0.Median lethal dose (LD50) and 90% lethal dose (LD90) with 90 ...
Jiao Meng (482119), Huan Yu (140826), Jian Xu (31545), Tong-xian Liu (5664841), Dun Wang (525747)   +4 more
core   +1 more source

Fifty percent mouse lethal dose (MLD₅₀) is inversely related to the pathogenicity index of avian H1N1 isolates.

, 2013
Fifty percent mouse lethal dose (MLD50) is inversely related to the pathogenicity index of avian H1N1 isolates.
Robert G. Webster (44422), Scott Krauss (36294), David E. Stallknecht (30534), Zeynep A. Koçer (314314), Jerold E. Rehg (150326)   +4 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Assessment of median lethal dose and anti-mutagenic effects of Glycyrrhiza glabra root extract against chemically induced micronucleus formation in Swiss albino mice -

, 2014
Background: To assess the median lethal dose and evaluate the anti-chemotherapeutic effects of hydro-methanolic root extract of Glycyrrhiza glabra on the cyclophosphamide (CP) induced mutagenicity in bone marrow cells of Swiss albino mice.
Varsha Sharma, R. Agrawal, V. Shrivastava   +2 more
semanticscholar   +1 more source

Absence of a dose-rate effect in the transformation of C3H 10T1/2 cells by α-particles [PDF]

, 1987
The findings of Hill et al. (1984) on the greatly enhanced transformation frequencies at very low dose rates of fission neutrons induced us to perform an analogous study with -particles at comparable dose rates. Transformation frequencies were determined
Fenn, S., Fromke, E., Kellerer, Albrecht M., Hieber, L., Ponsel, G., Roos, H.   +5 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Dose calculations for [¹³¹I] meta-iodobenzylguanidine-induced bystander effects

, 2014
Targeted radiotherapy is a potentially useful treatment for some cancers and may be potentiated by bystander effects. However, without estimation of absorbed dose, it is difficult to compare the effects with conventional external radiation treatment ...
R. J. Mairs, Seymour, C B, M. D. Gow, Mairs, R J, C. B. Seymour, Gow, M.D., Mothersill, C.E., Seymour, C.B., C. E. Mothersill, Mairs, R.J., M. Boyd, W. V. Prestiwch, Mothersill, C E, Prestiwch, W V, Prestiwch, W.V., Boyd, Marie, Boyd, M., Gow, M D   +17 more
core   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source