The Safety and Analgesic Effect of Datura Flos Pharmacopuncture in Sprague-Dawley Rats [PDF]
Background The aim of this study was to investigate the safety and analgesic effects of Datura Flos; pharmacopuncture (DFP). Methods The analgesic effects of DFP were assessed using mechanical (hot plate), chemical (formalin test), and thermal (von Frey ...
Seungah Jun +4 more
doaj +1 more source
Antioxidant Activity and Lethal 50 Doses of Polyhydroxybutyrate Nanoparticles (PHB-NPs)
Preparing Polyhydroxybutyrate nanoparticles (PHB-NPs) in a safe, economical, and effective manner is one of the biggest challenges facing nanotechnology workers. The current study aims to find an effective and safe way to prepare PHB-NPs. Moreover, to find the antioxidant effect and lethal dose fifty (LD50) of prepared PHB-NPs.
null Jenan A. Ghafil +1 more
openaire +1 more source
Background: Scorpions are arachnids that have a generalist diet, which use venom to subdue their prey. The study of their trophic ecology and capture behavior is still limited compared to other organisms, and aspects such as trophic specialization in ...
Alejandra Arroyave-Muñoz +3 more
doaj +1 more source
Preliminary evaluation of the efficacy and safety of brimonidine for general anesthesia
Background To determine the hypnotic and analgesic effects of brimonidine, and evaluate its efficacy and safety for general anesthesia. Potentiation of pentobarbital sleeping time following brimonidine administration was observed in mice, as was the ...
Chen Bin +5 more
doaj +1 more source
Calculation of the Median Lethal Dose and Low Lethal Dose Using the CombiStats Biometric Software
The median lethal dose (LD50) and low lethal dose (LD10) are calculated in acute toxicity studies, as well as during specific activity assessment of some medicines.
P. V. Shadrin +3 more
doaj +1 more source
Toxicity of Methylcyclohexane and Its Effect on the Reproductive System in SD Rats
Objectives: There is limited data regarding the toxicity of methylcyclohexane, despite its wide use in rubber adhesives, paint diluents, and cleansing agents.
Hyeon-Yeong Kim +3 more
doaj +1 more source
Rapid Determination of Log 10 50% Lethal Doses or 50% Infective Doses [PDF]
A reference table is presented for rapid determination of 50% lethal doses or 50% infective doses after administering 10-fold serial dilutions of toxins, viruses, sera, etc., to six animals per dilution.
openaire +2 more sources
An experiment was conducted to estimate the lethal dose of the physical mutagen gamma ray in Kodomillet variety CO 3. Genetically pure seeds were treated with different doses of gamma rays viz., 100 Gy, 200 Gy, 300 Gy, 400 Gy and 500 Gy.
J Poornima Jency +3 more
doaj +1 more source
Acute Toxicity Study of Methanol Extract of Baobab (Adansonia digitata Linn) Fruit Shell Extract in Mice [PDF]
Background: The natural origin of medicinal plants does not guarantee their safety, as there are no sufficient studies on the safety, efficacy, and toxicity to support their benefit claims.
Inna Muhammad Fannami +3 more
doaj
Screening of Compounds Toxicity against Human Monocytic cell line-THP-1 by Flow Cytometry
The worldwide rapid increase in bacterial resistance to numerous antibiotics requires on-going development of new drugs to enter the market. As the development of new antibiotics is lengthy and costly, early monitoring of compound's toxicity is essential
Pick Neora +3 more
doaj +1 more source

