Virulence network of interacting domains of influenza a and mouse proteins
Frontiers in Bioinformatics, 2023 There exist several databases that provide virus-host protein interactions. While most provide curated records of interacting virus-host protein pairs, information on the strain-specific virulence factors or protein domains involved, is lacking.
Teng Ann Ng +2 more
doaj +1 more source
Transfer of Radio-Adaptation via Serum: A Preliminary Report [PDF]
Iranian Journal of Medical Physics, 2020 Introduction: Adaptive response is one of the important concepts in radiobiology. The present report aimed to transfer the radio-adaptation via serum.
Ehsan Khodamoradi +6 more
doaj +1 more source
Zebrafish Sensitivity to Botulinum Neurotoxins
Toxins, 2016 Botulinum neurotoxins (BoNT) are the most potent known toxins. The mouse LD50 assay is the gold standard for testing BoNT potency, but is not sensitive enough to detect the extremely low levels of neurotoxin that may be present in the serum of sensitive ...
Kamalakar Chatla +4 more
doaj +1 more source
Effect of Linezolid on the 50% Lethal Dose and 50% Protective Dose in Treatment of Infections by Gram-Negative Pathogens in Naive and Immunosuppressed Mice and on the Efficacy of Ciprofloxacin in an Acute Murine Model of Septicemia [PDF]
Antimicrobial Agents and Chemotherapy, 2012 ABSTRACTMurine models of infection were used to study the effect of linezolid on the virulence of Gram-negative bacteria and to assess potential pharmacodynamic interactions with ciprofloxacin in the treatment of these infections, prompted by observations from a recent clinical trial.
Andrea, Marra +8 more
openaire +2 more sources
Veterinary Medicine and Science, 2021 Background Scorpion stings comprise a serious problem throughout the globe, especially in regions where they are more frequent. Despite a recent upsurge of interest in scorpion venoms by various research groups, there remain many challenges.
Ani Boghozian +4 more
doaj +1 more source
Acute Toxicity (Lethal Dose 50 Calculation): Medicine as a Life Saver or Destroyer
International Journal of Advance Research and Innovation, 2019 Lethal dose (LD 50) has been calculated. Different-testing methods have been used. The observed values have been plotted by Dose-Response against measured response and dose. Different LD value shows that all substances are poison. It depend on the amount of dose whether a substance is poison or remedy.
Malvika Chaudhary, Alka ., Sajid Ali
openaire +1 more source
Synthesis, spectral characterization, lethal dose (LD50) and acute toxicity studies of 1,4-Bis(imidazolylazo)benzene (BIAB) [PDF]
Heliyon, 2021 The preparation and spectral identification of new heterocyclic azo ligand 1,4-Bis(imidazolylazo)benzene (BIAB) was prepared by reacting a diazonium chloride salt solution of 1,4-diaminobenzene with imidazole in alkaline ethanolic solution. Differing spectral techniques have been used to study the structure of the azo dye ligand (BIAB) such as ...
Hussein Ali Kadhim Kyhoiesh +3 more
openaire +3 more sources
Listeria monocytogenes intragastric and intraperitoneal approximate 50% lethal doses for mice are comparable, but death occurs earlier by intragastric feeding [PDF]
Infection and Immunity, 1990 The intraperitoneal (i.p.) and intragastric (i.g.) mouse approximate 50% lethal dose values (ALD50S) were determined for 15 food and clinical isolates of Listeria monocytogenes. Although all strains gave i.g. ALD50S comparable to or less than their i.p. ALD50S, the i.g.
L, Pine, G B, Malcolm, B D, Plikaytis
openaire +2 more sources
Prediction of Human Lethal Doses and Concentrations of MEIC Chemicals from Rodent LD 50 Values: An Attempt to Make Some Reparation [PDF]
Alternatives to Laboratory Animals, 2021 The prediction of human toxicities from animal toxicity tests is often poor, and is now discouraged and in some cases banned, especially those involving the LD 50 test. However, there is a vast number of historical LD 50 data in both public and in-house
John C, Dearden, Mark, Hewitt
openaire +2 more sources
Radiosensitivity of Two Local Chili Varieties to Gamma Rays
Jurnal Teknik Pertanian Lampung, 2023 Genetic variation is needed for developing new superior varieties in plant breeding. Genetic variation of chili plants could be increased by inducing mutation with gamma rays irradiation.
Makhziah Makhziah +1 more
doaj +1 more source