Results 31 to 40 of about 3,844,636 (291)
Инфекция и иммунитет, 2020 Here, we review the data on mechanisms inhibiting cytotoxic effect of anthrax toxin on the immune system cells. Various disease forms, immunopathogenesis and contemporary methods for anthrax treatment are discussed.
V. V. Firstova +2 more
doaj +1 more source
Designed Azolopyridinium Salts Block Protective Antigen Pores In Vitro and Protect Cells from Anthrax Toxin [PDF]
, 2013 Background:Several intracellular acting bacterial protein toxins of the AB-type, which are known to enter cells by endocytosis, are shown to produce channels.
Barth, Holger +24 more
core +2 more sources
Plants, 2019 We exploited the advantages of genomic in situ hybridization (GISH) to monitor the introgression process at the chromosome level using a simple and robust molecular marker in the interspecific breeding of bulb onion (Allium cepa L.) that is resistant to ...
Ludmila Khrustaleva +6 more
doaj +1 more source
Kinetic energy less lethal weapons and their associated blunt trauma injuries [PDF]
, 2010 A widely used class of Less Lethal Weapon is the kinetic energy projectile. This can cause blunt trauma to the targeted person and, under certain circumstances, its use can result in permanent injury or death.
Tawell, Miles G.
core +2 more sources
Consequences and Utility of the Zinc-Dependent Metalloprotease Activity of Anthrax Lethal Toxin
Toxins, 2010 Anthrax is caused by the gram-positive bacterium Bacillus anthracis. The pathogenesis of this disease is dependent on the presence of two binary toxins, edema toxin (EdTx) and lethal toxin (LeTx). LeTx, the major virulence factor contributing to anthrax,
Jennifer Bromberg-White +2 more
doaj +1 more source
Design and use of a novel substrate for simple, rapid, and specific early detection of anthrax infection. [PDF]
PLoS ONE, 2018 Bacillus anthracis is a major biological warfare threat. The inhalation form of infection can kill quickly. While antibiotic treatment is effective, if diagnosis is delayed, the rapidly produced toxin may already be present in lethal amounts. This report
Kayana Suryadi, Nancy Shine
doaj +1 more source
Crystal structure of the anthrax lethal factor [PDF]
Nature, 2001 Lethal factor (LF) is a protein (relative molecular mass 90,000) that is critical in the pathogenesis of anthrax. It is a highly specific protease that cleaves members of the mitogen-activated protein kinase kinase (MAPKK) family near to their amino termini, leading to the inhibition of one or more signalling pathways.
Pannifer, A. D. +11 more
openaire +3 more sources
Toxins, 2015 The principal portal for anthrax infection in natural animal outbreaks is the digestive tract. Enteric exposure to anthrax, which is difficult to detect or prevent in a timely manner, could be exploited as an act of terror through contamination of human ...
Bruce Huang +4 more
doaj +1 more source
Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma [PDF]
, 1998 Macrophage migration inhibitory factor (MIF) is a potent proinflammatory mediator that has been shown to potentiate lethal endotoxemia and to play a potentially important regulatory role in human acute respiratory distress syndrome (ARDS).
N Hirani +15 more
core +1 more source