Insufficient Anthrax Lethal Toxin Neutralization Is Associated with Antibody Subclass and Domain Specificity in the Plasma of Anthrax-Vaccinated Individuals. [PDF]
Microorganisms, 2021 Smith K +10 more
europepmc +1 more source
Advanced Materials, EarlyView.This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle +9 more
wiley +1 more source
Pathogenetic Grounds of Principles of Depotentiation of Lethal Effects Y. pestis toxins
Проблемы особо опасных инфекций, 2012 Lethal combination of lypoplyssacharide and mouse Y. pestis toxin is decreased by the use of effective preparation - Cytoflavinum, the antihypoxant of substrate and regulatory activity.
G. A. Afanas'eva, N. P. Chesnokova
doaj +1 more source
Advanced Materials, EarlyView.This review describes recent developments in the design and synthesis of metal–organic frameworks (MOF)/textile composites for the detoxification of chemical warfare agent and simulants with extensive discussion on the advantages and disadvantages of different methods.
Zhihua Cheng +4 more
wiley +1 more source
Plesiomonas shigelloides exports a lethal cytotoxic-enterotoxin (LCE) by membrane vesicles
Brazilian Journal of Infectious Diseases, 2016 Plesiomonas shigelloides isolated from water in Brazil was previously described as a hemorrhagic heat-labile cytotoxic-enterotoxin producer. We purified this toxin from culture supernatants using ion metallic affinity chromatography (IMAC) followed by ...
Marilucia Santos Ludovico +7 more
doaj
The safety evaluation of prebiotic isomalto-oligosaccharid on the liver and gill tissues in common carp (Cyprinus carpio) exposed to lethal concentrations of butachlor toxin [PDF]
بومشناسی آبزیان, 2017 The aim of this study was to evaluate the safety effects of prebiotic isomalto-oligosaccharid on the damage of liver and gill tissues in common carp exposed to lethal concentrations of toxin butachlor.
Aliakbar Hedayati +2 more
doaj
Recombinant anthrax lethal toxin inhibits cell motility and invasion in breast cancer cells through the dysregulation of Rho GTPases. [PDF]
Oncol Lett, 2021 El-Chami D +3 more
europepmc +1 more source
Engineering Magnetotactic Bacteria as Medical Microrobots
Advanced Materials, EarlyView.Magnetotactic bacteria (MTB) are living microorganisms that produce magnetosomes for navigation using the Earth's geomagnetic field. Their built‐in magnetic components, along with their intrinsic and/or modified biological functions, make them one of the most promising platforms for making future living and programmable microrobots.
Jiaqi Wang +9 more
wiley +1 more source
Engineering Bacterial Secretion Systems for Enhanced Tumor Imaging and Surgical Guidance
Advanced Materials, EarlyView.This study presents a novel contrast agent platform, Streptavidin Associated Salmonella (SAS), for fluorescence image guided surgery. SAS selectively colonizes tumors and secretes streptavidin, enabling precise delineation of invasive tumor margins with prolonged signal retention.
Dohee Lee +14 more
wiley +1 more source
Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation
Advanced Science, EarlyView.At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao +14 more
wiley +1 more source