Results 201 to 210 of about 94,541 (354)

Adenylate cyclase toxin is critical for colonization and pertussis toxin is critical for lethal infection by Bordetella pertussis in infant mice

, 1990
Mary Goodwin-Trotman, Alison A. Weiss
openalex   +1 more source

Bacillus anthracis lethal toxin induces TNF-α–independent hypoxia-mediated toxicity in mice [PDF]

, 2003
Mahtab Moayeri, Diana C. Haines, Howard A. Young, Stephen H. Leppla   +3 more
openalex   +1 more source

Bimetallic Plasmonic Nanozyme‐Based Microneedle for Synergistic Ferroptosis Therapy of Melanoma

Advanced Science, EarlyView.
A microneedle (MN) patch that integrates novel bimetallic plasmonic nanozyme (BPNzyme) and traditional Chinese medicine β‐elemene (β‐ELE) has been rationally designed for ferroptosis pathway‐dependent combined therapy of melanoma. Abstract Melanoma is the most common malignant skin tumor, characterized by complexity, invasiveness, and heterogeneity ...
Wei Duan, Keying Xu, Yue Gao, Sheng Huang, Xueqian Xia, Xiang Liu, Shuangxue Pan, Chunpeng Jiao, Weijian Cheng, Yong Guo, Jingwen Zhao, Jia‐Wei Shen   +11 more
wiley   +1 more source

Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells.

, 1992
Naveen Arora, Kurt R. Klimpel, Yogendra Singh, Stephen H. Leppla   +3 more
openalex   +1 more source

808. Rapid Protective Immunity Evoked Against Anthrax Lethal Toxin Following a Single Intramuscular Administration of an Adenovirus-Based Vaccine Coding for Humanized Protective Antigen [PDF]

, 2003

openalex   +1 more source

Exosomal CMTM4 Induces Immunosuppressive Macrophages to Promote Ovarian Cancer Progression and Attenuate Anti‐PD‐1 Immunotherapy

Advanced Science, EarlyView.
In ovarian tumors with high CMTM4 expression, exosomes transfer CMTM4 to macrophages, upregulating ICAM1 and promoting M2 polarization via p65 nuclear translocation. This suppresses immunity by increasing PD‐1 and Tregs while reducing CD8+ T cells.
Bo Yin, Jianyi Ding, Jie Liu, Haoran Hu, Yashi Zhu, Meiqin Yang, Huijuan Zhou, Baoyou Huang, Tiefeng Huang, Mengjie Li, Yinyan He, Ang Li, Lingfei Han   +12 more
wiley   +1 more source

Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis.

, 1991
Conrad P. Quinn, Yogendra Singh, Kurt R. Klimpel, S H Leppla   +3 more
openalex   +1 more source

High Bactericidal Efficiency of Type IIA Phospholipase A2 against Bacillus anthracis and Inhibition of Its Secretion by the Lethal Toxin [PDF]

, 2004
Alejandro Piris Gimenez, Yongzheng Wu, Miguel Payá, Christophe Delclaux, Lhousseine Touqui, Pierre L. Goossens   +5 more
openalex   +1 more source

The N-end rule ubiquitin ligase UBR2 mediates NLRP1B inflammasome activation by anthrax lethal toxin. [PDF]

EMBO J, 2019
Xu H, Shi J, Gao H, Liu Y, Yang Z, Shao F, Dong N.   +6 more
europepmc   +1 more source

Precision‐Guided Stealth Missiles in Biomedicine: Biological Carrier‐Mediated Nanomedicine Hitchhiking Strategy

Advanced Science, EarlyView.
Diagram illustrating the binding methods of NPs and biological barriers. The biological carrier‐mediated nanomedicine hitchhiking strategy (BCM‐NHS) utilizes two distinct techniques: the surface‐based “Backpack” method, which relies on ligand‐receptor binding, covalent conjugation, and non‐covalent binding, and the encapsulated “Trojan horse” approach,
Yuyan Zhou, Xinyue Wang, Deyu Zhang, Hanxiao Cui, Xiaorong Tian, Wei Du, Zhenghui Yang, Dongling Wan, Zhiwei Qiu, Chao Liu, Zhicheng Yang, Lizhihong Zhang, Qiusheng Yang, Xuefeng Xu, Wenhao Li, Dong Wang, Haojie Huang, Wencheng Wu   +17 more
wiley   +1 more source