Hormonal, follicular and endometrial dynamics in letrozole-treated versus natural cycles in patients undergoing controlled ovarian stimulation [PDF]
Reproductive Biology and Endocrinology, 2011 The objective of this study was to compare letrozole-stimulated cycles to natural cycles in 208 patients undergoing intrauterine insemination (IUI) between July of 2004 and January of 2007. Group I (n = 47) received cycle monitoring only (natural group),
Brunengraber Lisa N +5 more
doaj +4 more sources
Protective Effects of Hesperidin on Letrozole-Induced Neurotoxicity: Involvement of Oxidative Stress, Apoptotic Signaling, and Inflammation. [PDF]
J Biochem Mol ToxicolLetrozole induces neurotoxicity by promoting oxidative stress, inflammation, and apoptotic signaling in the brain. Hesperidin co‐treatment mitigates these effects by restoring redox balance, suppressing pro‐inflammatory cytokines, and normalizing Bax/Bcl‐2–mediated apoptotic pathways, thereby exerting neuroprotective effects.
Ayhan İ +4 more
europepmc +2 more sources
The Gut Microbiome Is Altered in a Letrozole-Induced Mouse Model of Polycystic Ovary Syndrome. [PDF]
, 2016 Women with polycystic ovary syndrome (PCOS) have reproductive and metabolic abnormalities that result in an increased risk of infertility, diabetes and cardiovascular disease.
Kelley, Scott T +3 more
core +8 more sources
Letrozole treatment of pubertal female mice results in activational effects on reproduction, metabolism and the gut microbiome. [PDF]
, 2019 Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive-aged women that is comprised of two out of the following three features: hyperandrogenism, oligo- or amenorrhea, or polycystic ovaries. In addition to infertility, many women
Arroyo, Pablo +4 more
core +2 more sources
Neoadjuvant endocrine therapy for luminal breast cancer treatment: a first-choice alternative in times of crisis such as the COVID-19 pandemic [PDF]
, 2020 The epidemiological emergency caused by CoV-2 (COVID-19) has changed priorities in breast cancer management. In those places where the pandemic has had the greatest effect, it is of paramount importance for most patients to be at home, reducing or ...
Martí, Covadonga +1 more
core +1 more source
Comparison of Treatment Outcomes of Infertile Women by Clomiphene Citrate and Letrozole with Gonadotropins Underwent Intrauterine Insemination [PDF]
Acta Medica Iranica, 2012 This study was designed to compare the effect of clomiphene and letrozole in ovulatory stimulation in infertile women under intrauterine insemination who referred to Mahdiyeh infertility clinic during 2008-2009.
Shahrzad Zadehmodares +4 more
doaj +1 more source
Journal of Ovarian Research, 2022 Background Letrozole has been reported to be effective in treating anovulation, preventing ovarian hyperstimulation syndrome (OHSS), and retrieving oocytes in breast cancer patients.
Fukiko Kasuga-Yamashita +10 more
doaj +1 more source
Life-history and hormonal control of aggression in black redstarts: blocking testosterone does not decrease territorial aggression, but changes the emphasis of vocal behaviours during simulated territorial intrusions [PDF]
, 2013 Introduction: Many studies in behavioural endocrinology attempt to link territorial aggression with testosterone, but the exact relationship between testosterone and territorial behaviour is still unclear and may depend on the ecology of a species.
Apfelbeck, Beate +4 more
core +2 more sources
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2022 Background Let-7 microRNAs (miRNAs) may contribute to neurodegeneration, including Alzheimer's disease (AD), but, they were not investigated in Streptozotocin (STZ)-induced AD.
Nada Alaa Moustafa +5 more
doaj +1 more source
Frontiers in Endocrinology, 2023 ObjectiveThe present study aimed to compare the effectiveness of two different doses of letrozole (2.5 mg and 5 mg daily) in an antagonist protocol for infertile women with normal ovarian reserve.MethodsThis retrospective cohort study included infertile ...
Jing Lin +6 more
doaj +1 more source