Results 91 to 100 of about 370,636 (381)
Mitochondrial leucine tRNA level and PTCD1 are regulated in response to leucine starvation [PDF]
Amino Acids, 2014 Pentatricopeptide repeat domain protein 1 (PTCD1) is a novel human protein that was recently shown to decrease the levels of mitochondrial leucine tRNAs. The physiological role of this regulation, however, remains unclear. Here we show that amino acid starvation by leucine deprivation significantly increased the mRNA steady-state levels of PTCD1 in ...
Schild, Christof +6 more
openaire +4 more sources
Recent Advances in Highly Luminescent Carbon Dots
Advanced Functional Materials, EarlyView.Here, a comprehensive summary of the advancements is provided in highly luminescent carbon dots across various luminescence bands since their discovery in 2004. It systematically covers the synthesis, structural characteristics, preparation strategies, and essential purification of these carbon dots, along with their applications in efficient ...
Yupeng Liu +6 more
wiley +1 more source
Dependence of Sidechain Rotamer Preference on Backbone Conformation: Relative Free Energy Calculations for Valine and Leucine [PDF]
arXiv, 2002 Three dimensional relative free energy calculations are used to directly calculate the dependence of the preferred sidechain rotamers for valine and leucine on the conformation of the backbone. Specifically, umbrella restrained molecular dynamics calculations are used to sample all of Ramachandran space for chi values surrounding the common rotameric ...
arxiv
Advanced Healthcare Materials, EarlyView.Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han +7 more
wiley +1 more source
Aquaculture, Fish and Fisheries, Volume 2, Issue 6, Page 540-551, December 2022., 2022 Abstract Feed effectors have been suggested to improve the efficiency of plant‐based shrimp diets by increasing attractability and palatability. This research trial aimed to expand upon previous Pacific white shrimp (Litopenaeus vannamei) research involving plant‐based diets, feed effectors and passive acoustic monitoring (PAM) in a laboratory setting ...
Samuel Walsh +4 more
wiley +1 more source
The Processing Space of the Spray-Dried Mannitol-Leucine System for Pulmonary Drug Delivery
PharmaceuticsDesigning spray-dried particles for inhalation aims at specific physicochemical properties including a respirable aerodynamic diameter and adequate powder dispersibility. Leucine, an amphiphilic amino acid, has been shown to aid in optimizing bulk powder
Riley T. Schweizer +4 more
doaj +1 more source
Inorganic Nanomaterials Meet the Immune System: An Intricate Balance
Advanced Healthcare Materials, EarlyView.Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli +3 more
wiley +1 more source
The nutritional support to prevent sarcopenia in the elderly
Frontiers in NutritionSarcopenia has been described as a muscle disease, with multiple adverse consequences on human health. Recommendations aimed at supporting awareness, prevention, early detection and treatment of this disease are needed.
Attilio Giacosa +3 more
doaj +1 more source
Investigating Voice as a Biomarker for leucine-rich repeat kinase 2-Associated Parkinson's Disease [PDF]
arXiv, 2018 We investigate the potential association between leucine-rich repeat kinase 2 (LRRK2) mutations and voice. Sustained phonations ('aaah' sounds) were recorded from 7 individuals with LRRK2-associated Parkinson's disease (PD), 17 participants with idiopathic PD (iPD), 20 non-manifesting LRRK2-mutation carriers, 25 related non-carriers, and 26 controls ...
arxiv
Nutrients, 2015 Leucine is a well-known activator of the mammalian target of rapamycin (mTOR). Because mTOR signaling regulates several aspects of metabolism, the potential of leucine as a dietary supplement for treating obesity and diabetes mellitus has been ...
João A B Pedroso +2 more
semanticscholar +1 more source