Results 161 to 170 of about 370,636 (381)

Protease‐Mediated Synthesis of Zein Nanofibrils: From Structural Elucidation to Functional Application

Advanced Science, EarlyView.
The globular shape and hydrophobicity of zein made it unsuitable to be processed in pure aqueous environment. Pepsin‐mediated hydrolysis converts zein into water‐soluble and fibril‐forming peptides with a bioconversion rate exceeding 70%, enabling the self‐assembly of amyloid‐like nanofibrils.
Mingqin Li, Tonghui Jin, Simone Wüthrich, Jiangtao Zhou, Qiyao Sun, Ting Li, Zhou Dong, Eva Maria Zunzuneigui Bru, Raffaele Mezzenga   +8 more
wiley   +1 more source

An Insect Salivary Sheath Protein Triggers Plant Resistance to Insects and Pathogens as a Conserved HAMP

Advanced Science, EarlyView.
The salivary sheath protein myosin from SBPH is critical for the formation of the salivary sheath and feeding. However, myosin functions as a HAMP and triggered plant BAK1‐mediated PTI responses, which include the activation of calcium signaling pathways, MAPK phosphorylation, ROS bursts, and cell death, thereby triggering JA pathway.
Liangxuan Qi, Jing Li, Shuai Li, Jing Li, Han Wang, Lei Yang, Xinyang Tan, Zhichang Zhao, Guanghua Luo, Maofeng Jing, Ary A. Hoffmann, Jichao Fang, Rui Ji   +12 more
wiley   +1 more source

Mannose‐Glycated Metal‐Phenolic Microcapsules Orchestrate Phenotype Switch of Macrophages for Boosting Tumor Immunotherapy

Advanced Science, EarlyView.
Immunomodulatory metal‐phenolic microcapsules (mMPMs) is developed in this study that leverages dopamine‐modified hyaluronic acid and FeIII assemble on mannose‐glycated bovine serum albumin microbubbles. mMPMs effectively promote macrophage internalization and M1 polarization, enhancing pro‐inflammatory responses.
Xin Tan, Renwang Sheng, Weikun Li, Yinghua Tao, Zonghao Liu, Ning Yang, Syeda Safia Hashmi, Feiling Feng, Fangzhou Liu, Liqin Ge   +9 more
wiley   +1 more source

Nutritional strategies for improving sarcopenia outcomes in older adults: A narrative review

Pharmacology Research & Perspectives
Sarcopenia is characterized by a decline in muscle strength, generalized loss of skeletal muscle mass, and impaired physical performance, which are common outcomes used to screen, diagnose, and determine severity of sarcopenia in older adults.
Beatriz R. Goes‐Santos, Brian P. Carson, Guilherme Wesley Peixoto daFonseca, Stephan von Haehling   +3 more
doaj   +1 more source

Leucine-Sensitive Hypoglycæmia [PDF]

Proceedings of the Royal Society of Medicine, 1970
G. Tevaarwerk, M. Hartog, C. Lowy, T. R. Fraser   +3 more
openaire   +3 more sources

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Zusammensetzung des Leucins [PDF]

Archiv der Pharmazie
n ...
openaire   +2 more sources

A Dual‐Response DNA Origami Platform for Imaging and Treatment of Sepsis‐Associated Acute Kidney Injury

Advanced Science, EarlyView.
A dual‐response DNA origami platform is developed for the early diagnosis and therapeutic intervention of sepsis‐associated acute kidney injury. Abstract Current diagnostics for sepsis‐associated acute kidney injury (SA‐AKI) detect kidney damage only at advanced stages, limiting opportunities for timely intervention. A DNA origami‐based nanoplatform is
Yingying Zhao, Yadan Zhao, Yufan Ling, Zhiming Chen, Xiaofeng Wu, Xing Lu, Yao He, Houyu Wang, Fenglin Dong   +8 more
wiley   +1 more source

THE OCCURRENCE OF l-LEUCINE IN SWEET CLOVER SILAGE. [PDF]

, 1917
G. P. Plaisance
openalex   +1 more source

Host Plasma Microenvironment in Immunometabolically Impaired HIV Infection Leads to Dysregulated Monocyte Function and Synaptic Transmission Ex Vivo

Advanced Science, EarlyView.
Network‐based risk stratification of people living with HIV (PWH) on prolonged therapy using multi‐omics data identifies 44% of the patients are at risk of immunometabolic complications. A senescence‐associated myeloid cell‐driven plasma microenvironment drives immunometabolic dysregulation in at‐risk PWH.
Flora Mikaeloff, Marco Gelpi, Alejandra Escós, Tianqi Wang, Soham Gupta, Anna Olofsson, Sara Svensson Akusjärvi, Sabrina Schuster, Prajakta Naval, Vikas Sood, Negin Nikouyan, Andreas D. Knudsen, Beate Vestad, Julie Høgh, Johannes R. Hov, Thomas Benfield, Marius Trøseid, Vinay Pawar, Marijana Rucevic, Rui Benfeitas, Ákos Végvári, Liam O'Mahony, Rajkumar Savai, Niklas K. Björkström, Magda Lourda, João Pedro de Magalhães, Siegfried Weiss, Adil Mardinoglu, Mukesh Kumar Varshney, Annika C. Karlsson, Yasir Ahmed Syed, Susanne D. Nielsen, Ujjwal Neogi   +32 more
wiley   +1 more source