Hypoglycæmic Response to Leucine in a Leucine-sensitive Man [PDF]
Nature, 1960 IT has been reported previously1,2 that certain individuals show a profound lowering of the blood glucose-level following ingestion of leucine or iso-valeric acid and that this is a familial trait.
P. H. Wright +3 more
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Microbiota based personalized nutrition improves hyperglycaemia and hypertension parameters and reduces inflammation: a prospective, open label, controlled, randomized, comparative, proof of concept study [PDF]
PeerJBackground Recent studies suggest that gut microbiota composition, abundance and diversity can influence many chronic diseases such as type 2 diabetes.
Gopalakrishna Kallapura +6 more
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Leucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice [PDF]
, 2014 Kristyn A Liu1†, Laura M Lashinger1†, Audrey J Rasmussen1† and Stephen D Hursting12* Author Affiliations 1 Department of Nutritional Sciences, University of Texas at Austin, Austin, TX 78723, USA 2 Department of Molecular Carcinogenesis, University ...
Hursting, Stephend D. +3 more
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Molecular basis of various forms of maple syrup urine disease in Chilean patients
Molecular Genetics & Genomic Medicine, 2021 Background Maple syrup urine disease (MSUD) is an autosomal recessive inherited metabolic disorder caused by the deficient activity of the branched‐chain α‐keto acid dehydrogenase (BCKD) enzymatic complex.
Diana Ruffato Resende Campanholi +12 more
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A critical examination of substoichiometric isotope dilution analysis using thymidine and leucine
Scientia Marina, 1999 Isotope dilution analysis is used to determine the specific activity of radiolabelled precursors such as 3H-thymidine and 3H-leucine incorporated into DNA or protein in environmental samples.
David F. Bird
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Efficacy and Mechanism Evaluation, 2022 Background: Angiotensin-converting enzyme inhibitors and leucine are promising potential treatments for sarcopenia. Neither has yet been tested in adequately powered randomised trials in patients with sarcopenia.
Miles D Witham +15 more
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Leucine Supplementation Improves Diastolic Function in HFpEF by HDAC4 Inhibition
Cells, 2023 Heart failure with preserved ejection fraction (HFpEF) is a complex syndrome associated with a high morbidity and mortality rate. Leucine supplementation has been demonstrated to attenuate cardiac dysfunction in animal models of cachexia and heart ...
Paula Ketilly Nascimento Alves +10 more
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Daily L-leucine supplementation in novice trainees during a 12-week weight training program. [PDF]
, 2011 PURPOSE: To investigate the effects of daily oral L-leucine ingestion on strength, bone mineral-free lean tissue mass (LTM) and fat mass (FM) of free living humans during a 12-wk resistance-training program. METHODS: Twenty-six initially untrained men (n
Ispoglou, T +3 more
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Fishes, 2023 The aim of this study was to investigate the effects of imbalanced dietary BCAAs, especially Leu, on the growth and BCAA metabolism in turbot. A control diet was formulated by keeping optimum levels of Leu, Ile and Val.
Lu Wang +6 more
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Expression of the Leucine Operon [PDF]
Journal of Bacteriology, 1966 Burns , R. O. (Cold Spring Harbor Laboratories of Quantitative Biology, Cold Spring Harbor, N.Y.), J. Calvo, P. Margolin, and H. E. Umbarger . Expression of the leucine operon. J. Bacteriol. 91: 1570–1576.
J. M. Calvo +3 more
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