Results 31 to 40 of about 378,426 (279)

Principles of diet therapy for sarcopenic obesity: A review

Терапевтический архив
Nutrition and physical activity play a key role in the onset and progression of sarcopenic obesity (SO). Therefore, dietary interventions are essential in comprehensive programs to prevent and treat this condition.
Е. V. Pavlovskaya, O. A. Kislyak, A. V. Starodubova   +2 more
doaj   +1 more source

Correlation between changes of amino acid spectrum and alopecia in patients with obesity undergoing bariatric surgery: a prospective cohort study

Frontiers in Nutrition
PurposeTo investigate the association between serum amino acid changes and alopecia in patients with obesity before and after bariatric surgery, and identify risk factors for postoperative alopecia.MethodsThis prospective cohort study (ChiCTR2300074104 ...
Tingwen Wang, Tingwen Wang, Jiaqing Huang, Jiaqing Huang, Xin Sun, Hai Zhao, Jun Bao, Xuehui Chu, Xiaojie Bian, Xiaojie Bian   +9 more
doaj   +1 more source

Dietary Supplementation With Leucine or in Combination With Arginine Decreases Body Fat Weight and Alters Gut Microbiota Composition in Finishing Pigs

Frontiers in Microbiology, 2019
Obesity was associated with change in gut microbiota composition and their metabolites. We investigated the effects of dietary supplementation with leucine (Leu) in combination with arginine (Arg) or glutamic acid (Glu) on body fat weight, composition of
Chengjun Hu, Chengjun Hu, Fengna Li, Yehui Duan, Yulong Yin, Yulong Yin, Xiangfeng Kong   +6 more
doaj   +1 more source

Aumento acentuado da leucina como fator de mau prognóstico na doença da urina de xarope de bordo - relato de caso

Residência Pediátrica, 2023
INTRODUCTION: Leucinosis or Maple Syrup Disease (MSD) is an innate metabolism error caused by a deficiency in the activity of the alpha-keto acid-dehydrogenase enzyme complex, which leads to the accumulation of essential branched-chain amino acids ...
Bruna Duque de Almeida Braga, Gessianni Claire Alves de Souza, Filipe Marinho Pinheiro da Camara, Ana Cecília Menezes de Siqueira, Lucas Victor Alves   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Nutritional Practice and Nitrogen Balance in Elite Japanese Swimmers during a Training Camp

Sports, 2021
The protein requirement in athletes increases as a result of exercise-induced changes in protein metabolism. In addition, the frequency, quantity, and quality (i.e., leucine content) of the protein intake modulates the protein metabolism.
Ami Mizugaki, Hiroyuki Kato, Haruka Suzuki, Hidefumi Kurihara, Futoshi Ogita   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Anabolic response to essential amino acid plus whey protein composition is greater than whey protein alone in young healthy adults

Journal of the International Society of Sports Nutrition, 2020
Background We have determined the acute response of protein kinetics to one or two servings (6.3 g and 12.6 g) of a proprietary composition containing free-form essential amino acids (EAA) (3.2 g EAA per serving) and whey protein (2.4 g per serving), as ...
Sanghee Park, David D. Church, Gohar Azhar, Scott E. Schutzler, Arny A. Ferrando, Robert R. Wolfe   +5 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source