Results 31 to 40 of about 355,417 (306)

Acetyl-leucine slows disease progression in lysosomal storage disorders [PDF]

, 2020
Acetyl-DL-leucine is a derivative of the branched chain amino acid leucine. In observational clinical studies acetyl-DL-leucine improved symptoms of ataxia, in particular in patients with the lysosomal storage disorder, Niemann-Pick disease type C1. Here,
Cortina-Borja, M, Karl J Morten (16281605), Fineran, Paul, Smith, C, Spencer, John, Smith, De, Barry Boland (2011333), Platt, FM, Kaya, Ecem, Lauren Morris (2577274), Joanna Poulton (81462), Mario Cortina-Borja (130639), Smith, Claire, Brémovà-Ertl, Tatiana, Boland, Barry, Strupp, M, Strupp, Ml, Strupp, Michael, Spencer, J, Kaya, E, Boland, B, Morten, Karl J, Claire Smith (528058), Tatiana Bremova-Ertl (5639939), David A Smith (14591504), Ecem Kaya (9416438), Smith, DA, John Spencer (4461472), Bremova-Ertl, T, Poulton, Joanna, Paul Fineran (5639921), Morris, L, Platt, F, Cortina-Borja, Mario, Smith, David A, Poulton, J, Morris, Lauren, Frances M Platt (16212410), Platt, Frances M, Fineran, P, Morten, Kj, Michael Strupp (318710)   +41 more
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Construction and Application of Detection Model for Leucine and Tyrosine Content in Golden Tartary Buckwheat Based on Near Infrared Spectroscopy

Applied Sciences, 2022
To meet the demand of the breeding and processing industry of Golden Tartary buckwheat, quantitative identification models were established to test the content of leucine (Leu) and tyrosine (Tyr) in Golden Tartary buckwheat leaves by near-infrared ...
Liwei Zhu, Rebecca Njeri Damaris, Yong Lv, Qianxi Du, Taoxiong Shi, Jiao Deng, Qingfu Chen   +6 more
doaj   +1 more source

Characterization of the conglomerate form of acetyl-dl-leucine by thermal analysis and solubility measurements [PDF]

, 2012
Starting from a mixture of enantiomers in solution, crystallization can generate different types of crystals. In order to determine which type of crystal is obtained in the case of acetylleucine, an active pharmaceutical ingredient (API), analytical ...
B. Biscans, Pena, Richard, S. Teychené, Estime, Nicolas, Biscans, Béatrice, R. Pena, N. Estime, Teychené, Sébastien, Autret, Jean Marie, J.M. Autret   +9 more
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Study of amino acids absorption and gut microbiome on consumption of pea protein blended with enzymes-probiotics supplement

Frontiers in Nutrition
The current randomized, double-blind, crossover clinical trial was conducted to evaluate changes in the amino acid absorption and gut microbiota on consumption of pea protein supplemented with an enzymes-probiotics blend (Pepzyme Pro).
Abhijit Rathi, Tejal Gaonkar, Debojyoti Dhar, Gopalakrishna Kallapura, Swati Jadhav   +4 more
doaj   +1 more source

Differential regulation of protein synthesis in skeletal muscle and liver of neonatal pigs by leucine through an mTORC1-dependent pathway

Journal of Animal Science and Biotechnology, 2012
Neonatal growth is characterized by a high protein synthesis rate that is largely due to an enhanced sensitivity to the postprandial rise in insulin and amino acids, especially leucine. The mechanism of leucine's action in vivo is not well understood. In
Suryawan Agus, Nguyen Hanh V, Almonaci Rosemarie D, Davis Teresa A   +3 more
doaj   +1 more source

Principles of diet therapy for sarcopenic obesity: A review

Терапевтический архив
Nutrition and physical activity play a key role in the onset and progression of sarcopenic obesity (SO). Therefore, dietary interventions are essential in comprehensive programs to prevent and treat this condition.
Е. V. Pavlovskaya, O. A. Kislyak, A. V. Starodubova   +2 more
doaj   +1 more source

The catalytic subunit of the system L1 amino acid transporter (Slc7a5) facilitates nutrient signalling in mouse skeletal muscle [PDF]

, 2014
The System L1-type amino acid transporter mediates transport of large neutral amino acids (LNAA) in many mammalian cell-types. LNAA such as leucine are required for full activation of the mTOR-S6K signalling pathway promoting protein synthesis and cell ...
Adel F M Ibrahim, Yun-Bo Shi, Mitchell, Fiona E., Grant English (527945), Peter M Taylor, Taylor Peter M., Poncet, Nadège, Fiona E Mitchell, Ibrahim Adel F. M., English, Grant, J. Simon C Arthur (527946), Nadège Poncet, Victoria A McGuire, Yun-Bo Shi (193634), Arthur J. Simon C, McGuire Victoria A., Adel F. M. Ibrahim (188343), Grant English, Taylor, Peter M., Ibrahim, Adel F. M., Poncet Nadège, Nadège Poncet (527942), Victoria A. McGuire (527944), Peter M. Taylor (527947), McGuire, Victoria A., English Grant, Arthur, J. Simon C; id_orcid, Mitchell Fiona E., Shi Yun-Bo, Fiona E. Mitchell (527943), Shi, Yun-Bo, J Simon C Arthur   +31 more
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Correlation between changes of amino acid spectrum and alopecia in patients with obesity undergoing bariatric surgery: a prospective cohort study

Frontiers in Nutrition
PurposeTo investigate the association between serum amino acid changes and alopecia in patients with obesity before and after bariatric surgery, and identify risk factors for postoperative alopecia.MethodsThis prospective cohort study (ChiCTR2300074104 ...
Tingwen Wang, Tingwen Wang, Jiaqing Huang, Jiaqing Huang, Xin Sun, Hai Zhao, Jun Bao, Xuehui Chu, Xiaojie Bian, Xiaojie Bian   +9 more
doaj   +1 more source

Expression of the Leucine Operon [PDF]

Journal of Bacteriology, 1966
Burns , R. O. (Cold Spring Harbor Laboratories of Quantitative Biology, Cold Spring Harbor, N.Y.), J. Calvo, P. Margolin, and H. E. Umbarger . Expression of the leucine operon. J. Bacteriol. 91: 1570–1576.
R O, Burns, J, Calvo, P, Margolin, H E, Umbarger   +3 more
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Data_Sheet_1_Clinical Features and Therapeutic Effects of Anti-leucine-rich Glioma Inactivated 1 Encephalitis: A Systematic Review.docx

, 2022
Background: Clinical presentations and treatment programs about anti-leucine-rich glioma inactivated 1 (LGI1) encephalitis still remain incompletely understood.Objective: This study analyzed the clinical features and therapeutic effects of anti-LGI1 ...
Jing Shi (16730), Ting Li (117885), Yuou Teng (11937731), Zhizhong Yang (9183268), Jinzhou Tian (462134), Mingwan Su (295101), Jingnian Ni (11937734), Mingqing Wei (11937737)   +7 more
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