Research progress in the role and mechanism of Leucine in regulating animal growth and development
Frontiers in Physiology, 2023 Leucine, a branched-chain amino acid, is essential in regulating animal growth and development. Recent research has uncovered the mechanisms underlying Leucine’s anabolic effects on muscle and other tissues, including its ability to stimulate protein ...
Shahab Ur Rehman +4 more
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Leucine-tRNA-synthase-2-expressing B cells contribute to colorectal cancer immunoevasion.
Immunity, 2022 Immunoregulatory B cells impede antitumor immunity through unknown features and mechanisms. We report the existence of leucine-tRNA-synthase-2 (LARS2)-expressing B cell (LARS B) subset with a transforming growth factor-β1 (TGF-β1)-dominant regulatory ...
Zhiqiang Wang +21 more
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Frontiers in Nutrition, 2021 Background: The “leucine trigger” hypothesis was originally conceived to explain the post-prandial regulation of muscle protein synthesis (MPS). This hypothesis implicates the magnitude (amplitude and rate) of post-prandial increase in blood leucine ...
Gabriele Zaromskyte +4 more
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Microbiota based personalized nutrition improves hyperglycaemia and hypertension parameters and reduces inflammation: a prospective, open label, controlled, randomized, comparative, proof of concept study [PDF]
PeerJBackground Recent studies suggest that gut microbiota composition, abundance and diversity can influence many chronic diseases such as type 2 diabetes.
Gopalakrishna Kallapura +6 more
doaj +2 more sources
Leucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice [PDF]
, 2014 Kristyn A Liu1†, Laura M Lashinger1†, Audrey J Rasmussen1† and Stephen D Hursting12* Author Affiliations 1 Department of Nutritional Sciences, University of Texas at Austin, Austin, TX 78723, USA 2 Department of Molecular Carcinogenesis, University ...
Hursting, Stephend D. +3 more
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Daily L-leucine supplementation in novice trainees during a 12-week weight training program. [PDF]
, 2011 PURPOSE: To investigate the effects of daily oral L-leucine ingestion on strength, bone mineral-free lean tissue mass (LTM) and fat mass (FM) of free living humans during a 12-wk resistance-training program. METHODS: Twenty-six initially untrained men (n
Ispoglou, T +3 more
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A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice
eLife, 2021 Can limb regeneration be induced? Few have pursued this question, and an evolutionarily conserved strategy has yet to emerge. This study reports a strategy for inducing regenerative response in appendages, which works across three species that span the ...
Michael J Abrams +11 more
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Food & Nutrition Research, 2016 Background: Leucine supplementation has been reported to improve lipid metabolism. However, lipid metabolism in adipose tissues and liver has not been extensively studied for leucine supplementation in mice fed with a high-fat/cholesterol diet (HFCD ...
Jun Jiao +7 more
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A route to anionic hydrophilic films of copolymers of l-leucine, l-aspartic acid and l-aspartic acid esters [PDF]
, 1975 A series of copolymers of l-leucine and β-benzyl-l-aspartate [Leu/Asp(OBz)] covering the range 30–70 mol % of l-leucine, was synthesized by the N-carboxyanhydride (NCA) method.
Bantjes, A., Feijen, J., Sederel, W.L.
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Effects of Leucine Administration in Sarcopenia: A Randomized and Placebo-controlled Clinical Trial
Nutrients, 2020 Treating sarcopenia in older individuals remains a challenge, and nutritional interventions present promising approaches in individuals that perform limited physical exercise.
F. Martínez-Arnau +9 more
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