Results 191 to 200 of about 285,613 (247)

How Growth Cones Sense Extracellular Cues and Drive Neuronal Migration

open access: yesBioEssays, EarlyView.
Migrating neurons and growing axons utilize structurally and functionally similar growth cones to detect guidance cues. Shared receptors and signaling pathways mediate cytoskeletal reorganization to direct movement. This conserved mechanism underlies both neuronal migration and axon extension, providing insights into neuronal development and potential ...
Takahiro Kanzawa   +3 more
wiley   +1 more source

Revisiting oxygen toxicity: evolution and adaptation to superoxide in a SOD-deficient bacterial pathogen. [PDF]

open access: yesmBio
Huete SG   +8 more
europepmc   +1 more source

Taking Down the Primary Cilium: Pathways for Disassembly in Differentiating Cells

open access: yesBioEssays, EarlyView.
Primary cilia are developmentally essential subcellular signaling compartments. However, many differentiated cells lack primary cilia, and cilia disassembly in these tissue contexts has been largely overlooked. We highlight several pathways for primary cilia loss and examine how changes in ciliation states could contribute to diverse pathologies ...
Carolyn M. Ott, Saikat Mukhopadhyay
wiley   +1 more source

AutoML‐Driven Soft Sensors for Real‐Time Monitoring of Amino Acids in Mammalian Perfusion Cultures

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Mammalian perfusion culture offers high productivity for complex biologics but presents operational challenges in maintaining process stability. Real‐time monitoring is essential to address such challenges while traditional analytical methods often fall short due to several limitations such as detection sensitivity and spectral overlap ...
Sun‐Jong Kim   +4 more
wiley   +1 more source

Genetic Divergence and Antibody Expression Influence the N‐Glycomes of CHO‐K1 and CHO‐S Cells

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT While Chinese hamster ovary (CHO) cells continue to be the workhorse of recombinant therapeutic protein production, decades of genetic divergence in the industrially relevant CHO‐K1 and CHO‐S cell lines, are likely to have resulted in differing glycosylation capabilities. Glycosylation can influence the efficacy, serum half‐life, and safety of
Roberto Donini   +6 more
wiley   +1 more source

Creating A Course Based Undergraduate Research Experience (CURE) Genetics Yeast Laboratory Course at Xavier University of Louisiana

open access: yesBiochemistry and Molecular Biology Education, EarlyView.
ABSTRACT Course‐based undergraduate research experiences (CUREs) are important for providing undergraduates with authentic research experiences. At Xavier University of Louisiana, a Genetics Laboratory CURE course was developed and implemented. The goals of developing this Genetics CURE laboratory course were: (1) to provide a large number of students ...
Joanna E. Haye‐Bertolozzi   +4 more
wiley   +1 more source

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