Sestrins in Carcinogenesis-The Firefighters That Sometimes Stoke the Fire. [PDF]
Haidurov A, Budanov AV.
europepmc +1 more source
How Growth Cones Sense Extracellular Cues and Drive Neuronal Migration
Migrating neurons and growing axons utilize structurally and functionally similar growth cones to detect guidance cues. Shared receptors and signaling pathways mediate cytoskeletal reorganization to direct movement. This conserved mechanism underlies both neuronal migration and axon extension, providing insights into neuronal development and potential ...
Takahiro Kanzawa+3 more
wiley +1 more source
Revisiting oxygen toxicity: evolution and adaptation to superoxide in a SOD-deficient bacterial pathogen. [PDF]
Huete SG+8 more
europepmc +1 more source
Taking Down the Primary Cilium: Pathways for Disassembly in Differentiating Cells
Primary cilia are developmentally essential subcellular signaling compartments. However, many differentiated cells lack primary cilia, and cilia disassembly in these tissue contexts has been largely overlooked. We highlight several pathways for primary cilia loss and examine how changes in ciliation states could contribute to diverse pathologies ...
Carolyn M. Ott, Saikat Mukhopadhyay
wiley +1 more source
AutoML‐Driven Soft Sensors for Real‐Time Monitoring of Amino Acids in Mammalian Perfusion Cultures
ABSTRACT Mammalian perfusion culture offers high productivity for complex biologics but presents operational challenges in maintaining process stability. Real‐time monitoring is essential to address such challenges while traditional analytical methods often fall short due to several limitations such as detection sensitivity and spectral overlap ...
Sun‐Jong Kim+4 more
wiley +1 more source
Achieving High Protein Quality Is a Challenge in Vegan Diets: A Narrative Review. [PDF]
Soh BXP+3 more
europepmc +1 more source
Genetic Divergence and Antibody Expression Influence the N‐Glycomes of CHO‐K1 and CHO‐S Cells
ABSTRACT While Chinese hamster ovary (CHO) cells continue to be the workhorse of recombinant therapeutic protein production, decades of genetic divergence in the industrially relevant CHO‐K1 and CHO‐S cell lines, are likely to have resulted in differing glycosylation capabilities. Glycosylation can influence the efficacy, serum half‐life, and safety of
Roberto Donini+6 more
wiley +1 more source
ABSTRACT Course‐based undergraduate research experiences (CUREs) are important for providing undergraduates with authentic research experiences. At Xavier University of Louisiana, a Genetics Laboratory CURE course was developed and implemented. The goals of developing this Genetics CURE laboratory course were: (1) to provide a large number of students ...
Joanna E. Haye‐Bertolozzi+4 more
wiley +1 more source
Protein Intake and Protein Quality Patterns in New Zealand Vegan Diets: An Observational Analysis Using Dynamic Time Warping. [PDF]
Soh BXP+4 more
europepmc +1 more source