Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács +9 more
wiley +1 more source
Understanding the complex relationship between amino acid absorption kinetics and postprandial muscle protein synthesis rates in healthy adults and critically ill patients. [PDF]
Witard OC, Prokopidis K, Deane CS.
europepmc +1 more source
Identification of compounds that inhibit the kinase activity of leucine-rich repeat kinase 2
Jason P. Covy, Benoit I. Giasson
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The influence of dietary supplementation with the leucine metabolite β-hydroxy-β-methylbutyrate (HMB) on the chemotaxis, phagocytosis and respiratory burst of peripheral blood granulocytes and monocytes in calves [PDF]
Roman Wójcik +4 more
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Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou +16 more
wiley +1 more source
Correction: Dai et al. Leucine Promotes Proliferation and Differentiation of Primary Preterm Rat Satellite Cells in Part through mTORC1 Signaling Pathway. <i>Nutrients</i> 2015, <i>7</i>, 3387-3400. [PDF]
Dai JM +5 more
europepmc +1 more source
This work reviews recent advances in Organic Semiconducting Single Crystals (OSSCs), focusing on mechanical flexibility for robust devices, polymorph control for precise phase selection, and interface engineering with self‐assembled monolayers to improve alignment and performance.
Alessando Fraleoni‐Morgera +3 more
wiley +1 more source
Spray-Drying Process Optimization and Modeling for an Inhaled Dry Powder of 5-Azacytidine for Treating Local and Metastatic Lung Cancer. [PDF]
Anderson RM +7 more
europepmc +1 more source

