An efficient artificial copper‐dependent Michaelase featuring a metal‐binding unnatural amino acid, e. g. bipyridyl alanine (BpyA), was optimized through directed evolution and applied in catalytic asymmetric additions of 2‐acetyl azaarenes to nitroalkenes.
Ru Jiang+3 more
wiley +2 more sources
Impact of Co-Spray Drying with Leucine or Trileucine on Aerosol Performance, In Vitro Dissolution, and Cellular Uptake of Colistin Powder Formulations for Inhalation. [PDF]
Huang Y+4 more
europepmc +1 more source
EVIDENCE THAT INSULIN RELEASE IS THE MECHANISM FOR EXPERIMENTALLY INDUCED LEUCINE HYPOGLYCEMIA IN MAN* [PDF]
John C. Floyd+3 more
openalex +1 more source
Using RNA‐seq and other bioinformatics analyses, three clusters of mitochondria related genes, including aldo‐keto reductase family 1 members B10 and B15 (AKR1B10, AKR1B15), alanyl‐tRNA synthetase 1 (AARS1), mitochondrial ribosomal protein S6 (MRPS6), mitochondrial calcium uniporter dominant negative subunit beta (MCUB) and dihydrolipoamide branched ...
Bin Wu+6 more
wiley +1 more source
Multiple roles of branched-chain amino acid metabolism in tumour progression. [PDF]
Wang L, Shi F, Cao Y, Xie L.
europepmc +1 more source
Metabolism of Leucine and Valine within the Rumen
Lawrence A. Menahan, L.H. Schultz
openalex +1 more source
A Comparison of Leucine- and Acetoacetate-induced Hypoglycemia in Man* [PDF]
Stefan S. Fajans+3 more
openalex +1 more source
Progress in research on osteoporosis secondary to SARS‐CoV‐2 infection
This review explores the potential mechanisms, complications, risk factors, and future research directions related to osteoporosis secondary to SARS‐CoV‐2 infection. Key mechanisms include an imbalance between osteoclast and osteoblast activity driven by direct viral effects on bone, inflammation, hypoxia, dysregulation of noncoding RNAs, and metabolic
Jinlong Wang+5 more
wiley +1 more source
Single‐Step Synthesis of a Heterometallic [Cu2PdL4]2+ Hybrid Metal–Organic Coordination Cage
A heterotrimetallic [Cu2PdL4]2+ lantern‐type cage has been synthesized in a single self‐assembly step from a low‐symmetry heterotopic ligand containing terminal groups with different metal coordination preferences, hybridizing the metallosupramolecular motifs of Cu4L4 and Pd2L4 cages.
Shannon Thoonen+10 more
wiley +2 more sources
Circulating branched-chain amino acids and the risk of major adverse cardiovascular events in the UK biobank. [PDF]
Sun W, Lin R, Li Y, Yao Y, Lu B, Yu Y.
europepmc +1 more source